Ground Breaking Research Shows Efficacy of Optiflow NHF

Stock Exchange Announcement
STOCK EXCHANGE LISTINGS: NEW ZEALAND (FPH), AUSTRALIA (FPH)

Ground Breaking Research Shows Efficacy of Optiflow™ Nasal High Flow Therapy

• World’s largest randomised controlled trial in nasal high flow therapy
• Results show significantly lower rates of escalation of care for infants on nasal high
flow
• Study used Fisher & Paykel Healthcare’s Optiflow Junior and AIRVO™ 2 system

Auckland, New Zealand, 23 March 2018 – New research has been published in the prestigious
New England Journal of Medicine that shows significant benefits of Optiflow nasal high flow
therapy for pediatric patients requiring respiratory support.

The Pediatric Acute Respiratory Intervention Study (PARIS) was conducted by the research team
at Lady Cilento Children’s Hospital in Brisbane, Australia, and led by Ms Donna Franklin and Dr
Andreas Schibler. The study is the largest nasal high flow (NHF) randomised controlled trial to
date, aiming to investigate if the early use of NHF in less intensive settings could prevent the need
for treatment escalation.

Results show that the use of NHF to treat bronchiolitis, the leading cause of pediatric hospital
admissions to Emergency Departments (EDs) worldwide, is an effective strategy to reduce the
level of care required in infants with bronchiolitis. 12% of infants in the NHF group required
escalation of care, compared to 23% in the standard oxygen therapy group.

The study consisted of 1,472 infants aged younger than 12 months, who were enrolled from 17
EDs and associated pediatric wards across Australia and New Zealand. NHF was delivered at a
flow rate of 2L/kg/min and standard oxygen therapy was delivered at a maximum flow of 2L/min.

Vice President – Products & Technology at Fisher & Paykel Healthcare, Andrew Somervell said,
“This study provides further, compelling evidence of the efficacy of our Optiflow nasal high flow
therapy. It is encouraging to see such a meaningful improvement to patient care. Having such
reputable and robust clinical evidence of the effectiveness of our therapy is very significant and will
help to drive change in clinical practice.”

Fisher & Paykel Healthcare provided product support for PARIS. The study can be viewed at the
following link:
http://www.nejm.org/doi/full/10.1056/NEJMoa1714855

About Fisher & Paykel Healthcare
Fisher & Paykel Healthcare is a leading designer, manufacturer and marketer of products and
systems for use in respiratory care, acute care, surgery and the treatment of obstructive sleep
apnea. The company’s products are sold in over 120 countries worldwide. For more information
about the company, visit our website www.fphcare.com
.

Ends

Contact:
Investors:
Marcus Driller
General Manager Corporate
marcus.driller@fphcare.co.nz
+64 (0) 27 578 9663
Media:
Rachel Reynolds
Senior Communications Manager
rachel.reynolds@fphcare.co.nz
+64 (0) 21 713 911