Another NZ Public Healthcare Providers Adopts Cxbladder

Company Announcement
16 August 2018
1

ANOTHER OF NEW ZEALAND’S PUBLIC HEALTHCARE PROVIDERS, HAUORA
TAIRAWHITI, ADOPTS CXBLADDER

Gisborne’s Hauora Tairāwhiti (Tairāwhiti District Health Board) to Implement Cxbladder Testing for
Urology Referrals

Cancer diagnostics company, Pacific Edge (NZX: PEB), will this month commence Cxbladder testing for Hauora
Tairāwhiti (TDHB) urology patients undergoing investigation of haematuria (blood in the urine) for diagnosis
and post-treatment surveillance of bladder cancer at Gisborne hospital.

Hauora Tairāwhiti, New Zealand’s eastern-most DHB includes many of New Zealand’s most remote rural
communities. Head of urology, Mr John Boulton noted that, “Cxbladder testing will help identify a number
of patients referred to urology, for whom an invasive cystoscopy can be safely avoided, while providing
patients with the reassurance that they do not have bladder cancer. Aside from the patient benefits, this will
also contribute to a more efficient urology service for the region.”

Brent Pownall, VP Commercial and Franchise at Pacific Edge, said: “The commercial adoption by Hauora
Tairāwhiti adds to the growing list of public healthcare providers signing up for Cxbladder. Timely, accurate
diagnosis, access and ease of use are important considerations in urologic health, and are the hallmarks of
Cxbladder.

“By including Cxbladder within the urology workup in regional settings such as New Zealand’s East Coast,
many patients can get the peace of mind that they don’t have bladder cancer from our easy-to-use urine
test, thereby avoiding a cystoscopy and the need to travel long distances to the hospital.”


ENDS

For more information contact:
David Darling
Chief Executive Officer
Pacific Edge Ltd
P: +64 (3) 479 5800

Company Announcement
16 August 2018
2
OVERVIEW www.pacificedgedx.com
Pacific Edge Limited (NZX: PEB) is a New Zealand publicly listed, cancer diagnostic company specialising in the discovery
and commercialisation of diagnostic and prognostic tests for better detection and management of cancer. The company
is developing and commercialising its range of Cxbladder bladder cancer tests globally through its wholly owned central
laboratories in New Zealand and the USA. The company’s products have been tested and validated in international
multi-centre clinical studies.

Pacific Edge has four proprietary, novel, accurate, molecular diagnostic products in-market providing actionable results,
and better detection and management of urothelial cancer. Cxbladder Triage, Detect and Monitor are available through
the company’s dedicated CLIA-certified laboratories for customers in New Zealand, Australia, Singapore and the USA.
Cxbladder Resolve launched in New Zealand in December 2016.

ABOUT Cxbladder Triage www.cxbladder.com
Cxbladder Triage combines the power of the genomic biomarkers with additional phenotypic and clinical risk factors to
accurately identify patients with haematuria who have a low probability of bladder cancer and may not require a more
extensive urological evaluation. Cxbladder Triage is a tool for use by clinicians and physicians in primary evaluation of
patients with haematuria and is intended to reduce the need for an expensive and invasive work-up in patients who
have a low probability of having urothelial carcinoma.

ABOUT Cxbladder Detect www.cxbladder.com
Cxbladder Detect enables the non-invasive detection of bladder and other urinary tract cancers from a small volume of
a patients’ urine. Cxbladder Detect was launched in 2013 in the USA and is commercially available in New Zealand,
Australia and the USA as a Laboratory Developed Test (LDT) from the company’s CLIA certified laboratories. Cxbladder
Detect provides clinicians with a quick, cost effective and accurate measure of the presence of the cancer as an effective
adjunct to cystoscopy.

ABOUT Cxbladder Monitor www.cxbladder.com
Cxbladder Monitor, the third test in the Cxbladder portfolio for urologists, is a proprietary, non-invasive, molecular
diagnostic test that combines genomic biomarkers measured from a small quantity of a patient’s urine, with patient
specific clinical factors to better monitor bladder cancer patients for recurrence. Bladder cancer has a recurrence rate
of 50-80% and requires life-long surveillance. Cxbladder Monitor accurately identifies patients with a prior history of
urothelial cancer (UC) whose Cxbladder Monitor score shows that they have a low probability of recurrent urothelial
carcinoma. Cxbladder Monitor is designed to be used as the preferred adjunct test to cystoscopy in the management of
patients for ongoing evaluation of recurrent bladder cancer.

ABOUT Cxbladder Resolve www.cxbladder.com
Cxbladder Resolve is a proprietary, non-invasive, molecular diagnostic test that combines genomic biomarkers
measured from a small quantity of a patient’s urine, with patient characteristics for the identification of patients who
are likely to have aggressive or more advanced bladder cancer. Cxbladder Resolve, when used as part of the primary
evaluation of haematuria and/or in conjunction with other Cxbladder tests (Triage, Detect), is designed to assist
clinicians by accurately identifying patients with a high probability of having high grade or late stage bladder cancer, for
whom alternative or expedited treatment options may be warranted, or who can be prioritised for further investigation
in high throughput settings.

Refer to www.cxbladder.com for more information.