AFT Pharmaceuticals’ completes another 3 deals

Market release

12 April 2019


AFT Pharmaceuticals’ completes another 3 deals: Painkiller Maxigesic IV
®
is
now licensed in Mexico together with Maxigesic
®
tablets in Switzerland and
Cyprus

Mexico
AFT Pharmaceuticals (‘AFT’) has further extended its strong partnership with the
Mexican company, Laboratories Expanscience Mexico SA (‘Expanscience Mexico’)
to out-license its patented combination painkiller, Maxigesic IV, to Mexico.

Maxigesic IV (Paracetamol 1000mg+ Ibuprofen 300mg solution for infusion) has
been developed as a line extension to Maxigesic tablets, for use post-operatively in
hospitals where patients cannot take an oral medicine. A major Phase 3 clinical trial
conducted in Texas and Maryland USA found that Maxigesic IV provided significantly
better pain relief than either paracetamol (acetaminophen) IV or ibuprofen IV alone in
the same doses. *

Expanscience Mexico is a wholly owned subsidiary of privately-owned French
pharmaceutical company, Laboratoires Expanscience S.A. (‘Expanscience’) which
already holds the French rights for the Maxigesic oral range.

AFT Managing Director, Dr Hartley Atkinson, says that he is very pleased to further
extend the company’s partnership with Expanscience Mexico who will be
commercializing the oral product line of Maxigesic product which includes tablets,
oral liquid, Maxigesic Rapid and dry powder sachets in Mexico. “With a population of
129 million (2017) we believe that Mexico represents great potential for the whole
product line including now Maxigesic IV” said Dr Atkinson.

AFT secures a further two countries in Europe
AFT’s focus on the significant European market, has advanced by securing new
Licensee partners in two new countries, both Switzerland and Cyprus.

In Switzerland where the total analgesic market size is US $ 176M**, a significant
local Swiss company will drive the registration and launch of Maxigesic tablets in this
market.

In Cyprus, Maxigesic tablets has been licensed to Medochemie. Maxigesic Tablets
has recently attained registration in Cyprus.

Further licensing agreements pending
“As indicated in our recent February shareholder update, we have a number of
transactions underway. It’s great to finalise a further three agreements but multiple
discussions are ongoing and we expect to conclude further agreements soon” said
Dr Atkinson.

Maxigesic IV launches starting this new FY20 financial year
The first launches of Maxigesic IV are projected to start from the end of the calendar
year. Importantly these first launches will also allow additional regulatory filings in a
number of other territories including Mexico which rely upon registration by key
regulators such as the TGA in Australia.

Maxigesic tablet new launches accelerating
“We are progressing launches in a further 13 countries presently with Maxigesic
tablet stock orders shipped or under manufacture which will further increase
International revenues in FY20. This includes a number of significant EU markets
such as France, Spain, Belgium and the Nordics” said Dr Atkinson.

[end of Release]

For more information


Dr Hartley Atkinson, CEO, AFT Pharmaceuticals Ltd
Phone: +64 9 488 0232
Email: hartley@aftpharm.com

About Ferghana
Ferghana Partners (New York, London, Boston) initiated these transactions and
provided strategic/financial advisory services to AFT Pharma.

About Expanscience Mexico SA
Laboratorios Expanscience Mexico, S.A. DE C.V., a company incorporated in
Mexico and having its registered office at Blvd Miguel Cervantes de Saavedra 233,
Colonia Grenada, C.P. 11520 México and wholly owned subsidiary of Laboratoires
Expanscience is a pharmaceutical company incorporated in France having its
registered office at 1 Place des Saisons 92048 Paris La Defense Cedex, Paris,
France

About Medochemie Ltd
Medochemie Ltd is a multinational pharmaceutical and consumer healthcare
company headquartered in Limassol, Cyprus. Medochemie develops, licenses,
manufactures, markets, and distributes branded generic and OTC products as well
as their own brands in more than 107 countries.

Reference
* Daniels SE et al. Efficacy and safety of an IV acetaminophen/ibuprofen
combination after bunionectomy. A randomized, double-blind, factorial, placebo-
controlled trial. Submitted for publication.
** Source: Statista, March 2019, Full year 2018.