TRUSCREEN GROUP LIMITED logo

Truscreen Investor Presentation

Insider/Shareholder Notice27 April 2020TRUIndustrials

INVESTOR PRESENTATION
April 2020

(NZX: TRU)

A world without cervical cancer
Cervical Cancer can and should be prevented.

Truscreenprovides an accurate, real time screening solution.

Our screening solution is ideal for communities that can’t

access conventional laboratory-enabled screening methods.

It is affordable and easy to learn.

Our purpose is to ensure that all women of screening age –no

matter who they are –can have access to quality screening.

2

Cervical cancer
is a major public health issue

Fourth most common cancer, affecting women

►570,000 new cases each year

►311,000 deaths p.a.

Young women in low and middle income

countries (LMIC) are most at risk

►Most diagnoses occur at age 35-44

►85% of cases and 87% of deaths occur in LMICs

1BN+ women of screening age in LMICs –this is our focus

3

90% coverage of HPV
Vaccination of girls

(by 15 years of age);

WHO has set a

target to eliminate

cervical cancer by

the end of the

century

WHO GLOBALTARGETS FOR 2030

70% coverage of screening

(70% of women are

screened with high-

performance tests by the

ages of 35 and 45 years)

and 90% treatment of

precancerous lesions;

Management of

90%of invasive

cancer cases








4

►LMICs –lowest screening rates, highest
incidence and mortality rates

►Innovative service delivery models are required,

if LMICs are to meet screening targets

►TruScreen’sdisruptive model offers this

•No reliance on lab infrastructure

•Accurate real time screening

•Easy to learn

•Affordable

►TruScreen already has a presence in many

of these markets –and the support of Key

Opinion Leaders, NGOs and government

organisations

The opportunity for

TruScreen

5

Access to screening
programs has been

limited due to:

TruScreen’s

solution is

ideal for

LMICs

Access to ‘’no lab’’,

accurate, simple to use

and affordable

screeningessential

TRUSCREEN HAS CLOSE TO 1bln WOMEN ELIGIBLE FOR

SCREENING IN KEY MARKETS

Russia (44m)

China (401M)

Middle East

(70M)

Vietnam (30M)

Zimbabwe (4M)

TruScreen’scurrent markets

Targeting commercial roll-out

►Lack of laboratory

infrastructure

►No HPV vaccination

programs

►Shortage of diagnostic

technicians

Mexico (31m)

India (302M)

6

Investment highlights
The onlyreal-time cervical screening method available in LMICs

Disruptive technology, high potential

Clinical and commercial validation

Attractive commercial modelPoised for growth

►Real-time, single visit, mobile screening

technology

►No lab infrastructure required, nurse

administered

►Recognisedby WHO, UNITAID and the Clinton

Health Access Initiative

►Sensitivity and specificity equal to, or better, than

alternative screening tools

►Clinically tested on over 40,000 women in 25

studies across 20 countries

►Established user base / KOL support in key markets

►Targeting large markets

►Lean distributor-based model

►Annuity revenue stream

►Ramping up in existing markets to deliver sales

growth amid COVID impact

►New markets (India, Vietnam) coming on board

►Manufacturing process enhancements to deliver

double-digit margin improvement

7

17. 4 %
8.8%

7. 3 %

5.3%

$0.10 (as at 23 April 2020)

$1M (as at 31 March 2020)

Consolidated Nominees

Browns Island Holdings Ltd

Waitara Trustees Limited

NZ Central Securities

Market cap

Share price

Cash position

NZ$21.1M (as at 23 April 2020)

Significant

shareholders

Financial overview ($NZD)

8

0.0 m

0.1 m

0.2 m

0.3 m

0.4 m

0.5 m

0.6 m

0.7 m

0.8 m

0.9 m

1.0 m

0.04

0.06

0.08

0.1

0.12

0.14

0.16

0.18

0.2

Apr-19Jun-19Aug-19Oct-19Dec-19Feb-20Apr-20

Volume (m)

Share price ($)

Volume

Charging station
TruScreen

Device

Single Use Sensor

(SUS)

How it works

►Low electrical charge and light

examines the cervix’s surface

►Uses algorithm to determine

if cervix tissue is normal or

abnormal

9

Competitive advantage
Patients

►Real-time results

►Painless

►Non-Invasive

TRUSCREEN

Clinics

►Objective readings

►Minimal training

►Cost effective

►Single visit

►Portable

Technology

►No requirement for lab

►User-friendly

►Accurate readings

PAP

Patients

►Repeat visit

►Scraping of cervix

Clinics

►Widely varying accuracy

►Human error

►Labour intensive

►Long wait times

(days/weeks/months)

►Vaccines don’t cover all

►HPV types

Technology

10

Compelling market opportunity
End customers

►NZD $166M

addressable market

p.a.*

►SUS creates annuity

revenue

►Co-investment

model with

distributors, lean

organizational

structure

TruScreen’slocal

distributors target:

►Public hospitals

►Private hospitals

►Public health

initiatives

►Governments

►Non-Government

Organisations

TruScreendevice

Single Use Sensors

(SUS)

*

Based on TruScreenachieving 5 per cent market share of developing markets’ cervical cancer screening age population screened once every three years

11

Sustainable ‘razor-blade’ revenue model

12
Video: Acceptance in one of our core markets (Russia)

Please click on the following link toupload the video, or copy and paste the link to your browser

https://truscreen.com/news/truscreen-market-acceptance-russia/

Listing on
NZAX

2014 Nov

2 017 D ec

CFDA approval for

second generation

device

Listing on

NZAX

2018 Jul

2018 Jul

Commence large

scale pilot with China

CDC and COGA

523%sales

growth in H1

2018 Oct

2018 Dec

Migration to NZX

Recognition

by World

Health

Organization

2019 May

2019 Sep

China COGA study

first screening results

exceed expectations

•Strengthen / growing team

•RecoveryCOVID-19

•Margin improvement

•Further roll-out in China &

Russia

•Setting commercial roll-out

in Vietnam and India

2020 -20222022 & onwards

•Rollout Gen3 device

•Rapid non-linear sales

growth

•Company growth to support

the sales

•Strategic partnerships

Setting the fundamentals Transformation

Rapid growth

2014 -2019

13

Our commercialization journey

Drive adoption in
established markets and

new markets

►Continue roll-out in more

established markets

(China, Russia, Zimbabwe)

►Drive adoption and

prepare roll-out in India

and Vietnam based on

successful clinical trials

finalized recently

►Seed in promising LMIC

markets (Eastern Europe,

Asia Pacific)

Relentless focus on

product quality and

innovation

►New Quality Assurance

(QA) systems

implementation

►Ongoing improvement of

device in line with

feedback from markets

►Generation 3 product

development and launch

Expanding clinical support

►New clinical publications

under MAC supervision

►Continue local trials to

ensure local KOL support

►Launch online education

module with certification

to prepare the company

for rapid expansion

Enhance team capabilities

►Hiring of high profile

executives with expertise

in medical devices / LMIC

markets (CEO, CTO)

►Leverage digital solutions

for QA, training &

education, sales support

►Grow the team in line with

sales progress/business

needs

►Establish on-going team

upskilling

14

Growth Strategy

China –Most Advanced Market & Largest
Opportunity

►Truscreen’slargest market (57% of sales)

►World’s largest cervical cancer market

►First distribution agreements signed in 2014

►Pilot program of 20,000 women with Centre

for Disease Control (CDC)

►Clinical study with Chinese Obstetricians &

Gynaecologists Association (COGA) of 20,000

women in public hospitals –results from

Hunan province released and exceeded

expectations

►Hospital usage of SUS: Up to 1,000 per month

Market

Screening

population

NGO/KOL

engagement

Pilot

program

Distribution/

sales

commenced

Number of

devices

installed

China

401MYesYesYes49

Mexico31MYesYesYes10

Russia44MYesYesYes29

India300MYesYesNo0

Zimbabwe

30MYesYesNo0

Vietnam26MYesYesNo0

Key Markets

15

Key markets

Key variances
Revenue

Gross Profit

Research and

Development

Marketing

►Initiated major initiativefor SUS cost reduction,

signinglong-term contract with SUS supplier

►Optimising total overheads via revisiting the external

suppliers network and ruthless prioritization of activities

►R&D costs reducing as product matures

►Investment in business capability and people

►Negatively impacted by COVID-19

►Chinese business gradually recovering after COVID-19

outbreak, expect improvement from Q2 2020

►R&D 2020 includes positive adjustment from 2019

Operating

EBITA

►Improved in 2020 with lower R&D spend and benefit of

positive adjustment on 2019 R&D receipt

KEY FINANCIALS

NZD (m)

FY17

Actual

FY18

Actual

FY19

Actual

FY20

Estimate

% Change

FY20/FY19

Sales0.60.81.91.3- 40%

Total Revenue

1.42.23.12.5- 19%

COGS

.47.741.40.9-

R&D

1.21.91.70.9-

Marketing

.56.39.29.47-

G&a

2.12.72.52.8-

EBITDA

(3.0)(3.6)(2.8)(1.7)+40%

Net Assets

14.311.611.39.8

Cash

and Cash

Equivalents

3.71.21.71.0-60%

Net Assets

►Net assets subject to audit review of carrying value of

intangibles given uncertainty of COVID-19

16

Financials

$0
$500,000

$1,000,000

$1,500,000

$2,000,000

$2,500,000

$3,000,000

$3,500,000

20192020

Total revenue

$1,200,000

$1,230,000

$1,260,000

20192020

R&D Income

$0

$200,000

$400,000

$600,000

$800,000

$1,000,000

20192020

Device revenue

$0

$200,000

$400,000

$600,000

$800,000

$1,000,000

$1,200,000

20192020

Consumables (SUS)

Full-Service Distribution Chanel

•SUS revenue will grow at a higher rate

thanDevicerevenue

•SUSrevenue will become a sustainable

recurring revenue stream

•The device has an expected lifetime

of 5-7 years and the SUS is used

once per test per patient

0 yrs.5 yrs.

Device

SUS

Device and SUS Revenue

Revenue, $NZ







18

►“Return to normal” in China –supporting business as

China recovers from COVID-19

►Implementation of improved electronic quality assurance

system

►Hire Chief Technology Officer

►Overhead reduction program via review of all external

suppliers and revisit priority activities

►SUS cost reduction program initiated > new contract terms

with SUS supplier, long-term agreement

►Continue to prepare for dual ASX listing

Milestones: Near-term

Business transformation underway







19

►Targeting double-digit percentage revenue growth despite

COVID-19 impact

►Further roll-out in China to reach installed devices

base of min 70 hospitals (+43% vs 2020)

►Continue with the roll-out in Russia and initiate the

roll-out in Vietnam and India

►Implementation of a comprehensive device traceability QA

system

►Achieve double digit percentage reduction of SUS cost to

boost GP

►Commence local device assembly in China

►Generation 3 development > improved product design in

line with customers’ feedback

Milestones: Next 12 months

Focus on rapid non-linear sales growth once

COVID-19 restrictions are lifted

CEO
VictoriaPotarina

►More than 20 years

commercial experience

►Previously worked at

Johnson and Johnson

across UK andEurope

►Heldpositions atmultiple

multinational companies in

theFMCG, over-the-

counter, medical devices

and healthcare sectors

CFO

Guy Robertson

►Chartered accountant with

30 years financial

management

and leadership experience

►CFO & Company Secretary

for TruScreen

GM International BD

Dr Jerry Tan

►Qualified gynaecologist

►Extensive experience in

China, and East Asia

►Oversees distributors,

market evaluation and

clinical trials

Chief Technology

Officer

►Expert in Healthcare

Compliance including

medical device licensing

and quality assurance

►Responsible for

manufacturing, research

and development,

registrations and quality

assurance

GM Quality &

Regulatory Compliance

Paul Curran

►Key role to be hired

20

Invigorated and experienced executive team

Chairman
Tony Ho

►Non-executive chairman of

Greenland Minerals (ASX:

GGG) and Bioxyne

(ASX:BXN)

►Chairmen of Cannasouth

Limited (NZX: CBD)

►Past NED of Hastings

Technology Metals

(ASX:HAS) and Brazin

(ASX:BRZ)

Non Executive Director

Christopher Horn

►Chair of Audit, Finance and

Risk Committee

►20 years as a partner of

KPMG and its predecessor

firms.

Non Executive Director

Chris Lawrence

►Experienced life science

and biotech investor

►Strong experience in high

growth companies,

particularly in biotech

sector

►Member of Audit, Finance

and Risk Committee

►Senior healthcare

executive with 30+ years

experience

in international and

medical device businesses

Non Executive Director

Con Hickey

21

Board of directors with extensive experience

Contacts
Tony Ho, Chairman

Victoria Potarina, CEO

Guy Robertson, CFO

www.truscreen.com

E: victoriapotarina@truscreen.com

22

APPENDIX
23

Market entry and
development

Build awareness

•Key opinion leader (KOL) engagement and

endorsement

•Medical conferences

•Clinical trials/studies

Expand global footprint

•Local distributorstrategy

•Public health initiatives

•Partnerships with Non-Government Organisationsand

Government agencies

Technology transfer to key markets

Doctor acceptance
(1)

•152 women surveyed at the Whittington Hospital,

London

82% preferred TruScreen

•2% preferred the Pap smear

•Main factors cited for TruScreenpreference were

immediate results, less pain or discomfort

•> 60% of doctors rated TruScreenat 4 – 5 out of 5

•The two main advantages cited were TruScreen’s

real time results and the absence of a need for

laboratory facilities and personnel

Patient acceptance

(2)

20

16

12

8

4

0

a.. Real-time results-

Patients are not lost to

follow-up

b. No laboratory

facilities or trained

cytologists needed

c. Objective, self-

checking procedures

ensure consistent and

reproducible results

d. High accuracy

and earlier

detection of

precancerous

lesions

e. Non-

invasive, less

discomfort to

women

25

Acceptance of TruScreen

TruScreen1 at Guadalajara (2016)Sensitivity to CIN2+ 78%Specificity 64%
TruScreen1 atLi Xia et al in China (2011)Sensitivity to CIN2+ 81.7%Specificity 79.6%

TruScreen1at Guangdong China (2010)Sensitivity to CIN2+ 78.8%Specificity 74.4%

TruScreen1 in Shandong China (2010)Sensitivity to CIN2+ 75%Specificity 85%

TruScreen’sperformance

Interim results RHW (2017): Excellent. 93% Negative Predictive Value

Interim results Hunan China (2019): Sensitivity: 89.29%; Specificity: 87.17%

PAP and HPV in TruScreen’smarkets – Sensitivity to CIN2+

Guadalajara (2016)HPV DNA 56%PAP 36%

TruScreenin Hunan China (2019)

HPV DNA 92.86%PAP 67.87%

TruScreen1at Guangdong China (2010)

PAP 42.2%

TruScreen1 in Shandong China (2010)

PAP 43%

26

Clinical Data

Professor Neville Hacker AM
•Professor Neville Hacker is conjoint Professor of Gynaecological

Oncology at the University of New South Wales and recently retired

from clinical practice after 32 years as the director of the

GynaecologicalCancer Centre, Royal Hospital for Women in Sydney,

where he continues to serve as an Emeritus Consultant.

•Heisa pastPresidentoftheSocietyofPelvicSurgeons. Heisa past

PresidentoftheInternationalGynaecologicalCancerSociety,former

ChairmanoftheOncologyCommitteeoftheRANZCOG,anda former

ChairmanofExaminersforGynaecologicOncology,RANZCOG.

Clinical Advisory - Professor of Gynaecological

Oncology

Colonel (Dr.) Michael J. Campion –

Chairman

•Colonel(Dr.) MichaelJ. Campionis a SeniorStaffSpecialistandHeadof

thePreInvasiveClinicattheGynaecologicalCancerCentreoftheRoyal

HospitalforWomeninSydneyandisa ConjointAssociateProfessor,

SchoolofWomen’sandChildren’sHealth,attheUniversityofNewSouth

Wales.Hehasover30years’experienceasaqualifiedmedical

practitionerandover20yearsofexperienceasanexpertcolposcopist.

•Inaddition,Dr. Campionis theDirector,HealthServicesArmyReserve–

EasternRegionfortheRoyalAustralianArmyMedicalCorpsandis both

aBoardmemberandNationalHospitaller,StJohnAmbulance,

Australia. Dr. Campionhaswrittennumerouspeerreviewedpapersand

chaptersoncervicalcancer,includingpapersonTruScreen.

RAAMC, CStJ, KM, KCHS, KLJ

27

Experienced medical advisory board

Intellectual property
•TruScreenuses trade secrets to ensure protection against IP

infringement

•Enumerated in the appendices to the Marrakesh Agreement

which established the World Trade Organisation

•Electro Optical Assembly

•Firmware

•Circuit Design and Printed Wire Assemblies (electronics)

•Single Use Sensor

•Algorithm

•Trademarks

•All testing protocol and manufacturing specifications

•China:

•Patent - Apparatus for Tissue Recognition Using Multiple Measurement

(ZL201210439914.9)

•Trademarks for “TruScreen” and “SUS” (English and Chinese equivalent)

IP coverage:

28

Disclaimers
This presentation should be viewed in conjunction with TruScreen’sFinancial Statements for the 12 months to 31 March 2019 and the accompanying NZX release. The information presented is a snapshot and does not contain

supporting information necessary to make an investment decision. It is not intended to act as a recommendation to acquire TruScreenshares. There can be no assurance that actual outcomes will not materially differ from the

forward looking statements presented. A number of important factors could cause actual results or performance to differ materially from the forward-looking statements. The forward-looking statements are based on information

available to TruScreenas at the date of this presentation. Except as required by law (including the NZAX Listing Rules), TruScreenundertakes no obligation to provide any additional or updated information whether as a result of new

information, future events or results or otherwise. TruScreen, its advisers, affiliates, related bodies corporate, directors, officers, partners, employees and agents make no representationor warranty, express or implied, as to the

currency, accuracy, reliability or completeness of information in this presentation.

29

Data sourced from publicly available filings. Our datasets may not be complete. Automated analysis can produce errors. If you believe any data on this page is incorrect, please contact us at hello@nzxplorer.co.nz. For informational purposes only. Not investment advice.