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Quarterly Update – Q4 23 Test Volumes Reach New Record

Quarterly Update17 April 2023PEBHealthcare

INSIDE
Letter from the CEO 02

Test volumes rise to a new record 03

Triage gains CMS coverage 04

Annual meeting: save the date 04

Kaiser integration progress 05

Israeli distribution agreement signed 06

Standing room only at SESAUA 06

New study microDRIVE launched 07

APAC President appointed 08

Profile: Dr Daniel Shoskes 09

APRIL 23

PACIFIC EDGE LIMITED INVESTOR UPDATE | APRIL 2023
2

Dear Shareholders,

The close of the March 2023 quarter

represents the completion of my

first full financial year leading Pacific

Edge. While we are still seeking

clarity over continued Medicare

coverage of our tests in the US, I am

pleased to share my sense of pride

with what we have achieved.

Throughout the year we have

laid the foundations for success and

resilience in the US by executing

on the strategic pillars outlined a

year ago 1) the adoption and more

frequent use of Cxbladder tests;

2) generating clinical evidence to

support Cxbladder coverage and

their inclusion in global standards

of care; and 3) continued innovation

over the long term.

Steady quarter-on-quarter

improvements have continued in the

final three months of FY23.

The volume of tests processed

in our laboratories reached a record

8,878 in the quarter (Q4 23) – a 14%

increase on the prior quarter (Q3

23) and up 42% on the same quarter

a year ago (Q4 22).

The result brings total testing

volumes for FY 23 to 31,566 – a 37%

uplift on FY 22’s 23,086 tests. The

number of US ordering clinicians has

also continued to rise (see page 3).

At the start of the third quarter,

Cxbladder Triage received a CPT

1


code and was added to the Novitas

Local Coverage Article (LCA 58917)

which Pacific Edge relies upon for

Medicare coverage for all our tests

in the US.

This development recognizes

that Triage now is covered subject

to medical necessity in the same

manner as Detect and Monitor.

Consequently, we expect it to

drive a modest improvement in

payment recoveries from Medicare

and Medicare Advantage payors.

However, we do not expect it to

drive a significant uplift in usage

of Triage in the US as we focus our

efforts on Detect

+

(see page 4).

The approach of gaining a

CPT code and the inclusion in the

LCA58917 also potentially offers

a faster and tangible path for

coverage for our new test Cxbladder

Detect

+

, assuming of course the

current or similar approach to

US reimbursement of our tests is

retained.

The integration of Cxbladder

into the Electronic Medical Records

system of our largest customer

Kaiser Permanente, has progressed,

but not as fast as we expected. The

development teams on both sides

have now completed the software

development and integration

testing, however, due to the

substantial nature of the integration

into a live system at Kaiser,

additional administrative and review

processes remain to be completed

(see page 5).

Despite these recently added

administrative requirements, the

Kaiser urologists, the innovation

group, the EMR implementation

team and the Pacific Edge team

continue to share a common goal

and a common commitment to

completion as soon as feasible.

Our evidence generation

program continues to evolve,

particularly in furtherance

of achieving guidelines

recommendations. Notably we have

launched a new study with the VA,

we have called microDRIVE, which in

combination with existing studies is

aimed at demonstrating the clinical

validity of Cxbladder Detect

+

in

detecting bladder cancer in patients

presenting with microhematuria.

Independent studies on the utility

of Cxbladder products meanwhile

continue to support the evidence

we gain from our own program (see

page 7 and 8).

Late in the quarter, we signed

a distribution agreement for

Cxbladder in Israel with the Tel

Aviv-based company ProGenetics as

we consider global markets with an

appetite for genomic oncology tests

that can be sent to our US Lab (see

page 6).

Finally, we continue to build

capability in the leadership team.

In this update we profile two new

members, Glen Costin who has

been appointed as our new APAC

President (page 8) and Dr Daniel

Shoskes, who joined a few months

ago as a Medical Director in our

Medical Affairs team.

Our focus now is firmly on

execution. We look forward to

updating shareholders on our

progress when we release our 2023

financial results in late May.

Ngā mihi,

Dr Peter Meintjes

Chief Executive

LETTER FROM THE CEO

A YEAR OF STEADY

STRATEGIC PROGRESS

1

Current Procedural Terminology code: a set of medical codes created and maintained by the American Medical Association that are used to describe medical, surgical,

and diagnostic services performed by healthcare providers in the United States.

UNIQUE ORDERING CLINICIANS: US
2

-

1,000

2,000

3,000

4,000

5,000

6,000

7,000

8,000

9,000

Q1 23Q2 23Q4 22Q3 22Q2 22Q1 22Q4 21Q3 21Q2 21Q1 21

Test volume

USNZ

2,791

3,110

3,824

4,277

4,706

4,591

5,290

6,073

6,699

1,073

1,079

1,074

1,117

952

983

1,165

Q3 23Q4 23

6,629

1,139

7,817

1,061

943

1,088

2,133

852

35%

CAGR

TOTAL TEST VOLUMES: GROUP

PACIFIC EDGE LIMITED INVESTOR UPDATE | APRIL 2023

3

TEST

VOLUMES

TEST VOLUMES RISE TO A NEW RECORD

Test volumes processed at Pacific Edge laboratories rose to a new record in the fourth quarter of the 2023

financial year (Q4 23) rising to 8,878 tests, a 14% rise on the 7,768 tests in the prior quarter (Q3 23).

The volume processed in Q4 23 represents a 42% incre

ase on the 6,242 tests processed in the same quarter of

the prior year (Q4 22). The result brings total volumes for FY 23 to 31,566 – a 37% increase on the 23,086 tests in the

prior financial year (FY 22).

US volumes led the growth

rising to 7,817 in Q4 23, an 18% increase on the 6,629 tests in Q3 23. The figure also

represents a 48% increase on the 5,290 tests processed in Q4 22. The result brings US test volumes for FY 23 to

27,2

18, an increase of 44% on the 18,864 in FY 22.

The number of unique ordering clinicians in the US has continued to grow through the quarter to 1,151 at the end

of Q4 23, up 6% on the 1,081 ordering in Q3 23 and up 46% on the 789 clinicians who ordered tests in Q4 22.

A

sia Pacific volumes in Q4 23 were 1,061 down 7% on the 1,139 tests processed in Q3 23, but up 11% on the 952

tests processed in Q4 22. Total APAC volumes for FY 23 were 4,348, a 3% increase on the 4,222 tests processed in

FY 22. The volume trends in APAC reflect the maturity of the New Zealand market and the region’s ongoing

h

ealthcare reforms.

2

Historic numbers of unique ordering clinicians in the US have changed slightly, correcting data recording inconsistencies determined by ongoing data provenance initiatives.

-

200

400

600

800

1,000

1,200

Q1 23Q2 23Q4 22Q3 22Q2 22Q1 22Q4 21Q3 21

Physicians

47%

CAGR

515

530

Q2 21Q1 21

411

462

657

690

741

789

895

980

Q3 23Q4 23

1,081

1,151

PACIFIC EDGE LIMITED INVESTOR UPDATE | APRIL 2023
4

MEDICARE COVERAGE

CXBLADDER TRIAGE GAINS

MEDICARE COVERAGE

SAVE THE DATE

CONNECT WITH

US AT OUR

2023 ANNUAL

MEETING

Pacific Edge’s 2023 Annual

Shareholders Meeting will this year

be held in Auckland and we will be

using it to connect shareholders

with the strategies we are using to

drive the success of Cxbladder in the

US market.

Pacific Edge Diagnostics USA

President David Levison and

VP of Medical Affairs, Dr Tamer

Aboushwareb, who are both on the

frontline of driving the adoption of

Cxbladder, will address the meeting

and take shareholder questions.

As usual our directors and senior

management will also be present to

meet shareholders. All shareholders

unable to join in person in Auckland

will be able to join virtually. More

detail on the meeting will be released

with the publication of our Annual

Report.

Where:


Link Mark

et Services

Board Room

Level 30, PwC Tower

15 Cus

toms Street West

A

uckland 1010

When:

3:00pm 2

7 July 2023

Connect virtually:

www.virtualmeeting.co.nz/peb23

3

Novitas has a policy of covering products on LCA 58917 under the 21st Century Cures Act, if

clinicians deem the tests medically necessary, until the publication of an LCD either covering or

denying coverage of a product.

4

Current Procedural Terminology code is a set of medical codes created and maintained by the

American Medical Association that are used to describe medical, surgical, and diagnostic services

performed by healthcare providers in the United States.

5

Lotan et al ‘Urinary Analysis of FGFR3 and TERT Gene Mutations Enhances Performance of

Cxbladder Tests and Improves Patient Risk Stratification’ J Urol. 2023 Apr; 209 (4): 762-772.

Cxbladder Triage, our test to assist clinicians to safely de-

intensify hematuria evaluation in populations with a low

incidence of bladder cancer, has now been included in the

Local Coverage Article (LCA 58917) that Pacific Edge currently

relies upon for Medicare coverage of all our tests in the US.

3

Novitas, the Medicare Administrative Contractor with

jurisdiction for Pacific Edge’s US laboratory, listed Triage in

its LCA in January as a test covered with medical necessity. It

follows the issuing of a CPT

4

code (0363U) in the third quarter

of the financial year.

We expect the development to lead to modest increases

in rates of payment from Medicare and Medicare Advantage

payors for Triage. We also see coding and listing in LCA 58917

as a faster more tangible path for our enhanced test Cxbladder

Detect

+

to gain coverage, should the current approach to

reimbursement of our tests in the US continue.

“We expect the development to lead to modest

increases in rates of payment from Medicare and

Medicare Advantage payors for Triage.”

T

hat said, we do not expect the development to drive a

significant increase in adoption of Triage in the US. Triage

currently makes up a small fraction of commercial testing

volume in the US outside of those contracted by our largest

US customer Kaiser Permanente. Triage also still needs a price,

established by Medicare through the national pricing process,

which will make reimbursement more reliable and timely by

Medicare and Medicare Advantage payors around the US.

Finally, going forward in the medium term, Pacific Edge plans

to promote Cxbladder Detect

+

rather than the existing Triage

test as the best test for risk stratification and de-intensifying

hematuria evaluation. This new approach follows the publication

in December

5

of clinical evidence that demonstrated the superior

performance of Detect

+

.

We also acknowledge the potential for Cxbladder Triage

to lose its coverage in the same way as Detect and Monitor if

a proposed Local Coverage Determination governing Genetic

Testing for Oncology (DL39365) were to be finalized without

changes and without addressing the comments and concerns

from Pacific Edge.

Novitas put forward DL39365 in July 2022, and must either

finalize or withdraw it within 12 months of the date of the

proposal.

PACIFIC EDGE LIMITED INVESTOR UPDATE | APRIL 2023
5

STRATEGIC ACCOUNTS

KAISER EMR INTEGRATION

TECHNOLOGICALLY COMPLETE

Pacific Edge has now completed

the software development

and integration testing on its

project to integrate Cxbladder

into the Electronic Medical

Records (EMR) system of Kaiser

Permanente. We continue to

complete the administrative

and review processes required

to be a registered supplier to

Kaiser Permanente to enable the

project to go live.

We are excited to have

achieved the important technical

milestones in the project, which

has spanned many teams and

many person-hours across

the Kaiser system, our team in

the US, and our team in New

Zealand.

We have significantly

de-risked the project and

importantly, the Kaiser urologists,

innovation group, EMR

implementation team and Pacific

Edge team continue to share a

common goal and a common

commitment to completion as

soon as feasible.

“Cxbladder tests have

improved access to

urology care as Kaiser

has emerged from the

pandemic.”

K

aiser Permanente Southern

California Permanente Medical

Group urologist Dr Ronald

Loo, MD, says the Cxbladder

tests have improved access

to urology care as Kaiser has

emerged from the pandemic

with unprecedented demand for

services.

“The very high negative

predictive value of the

Cxbladder tests have allowed

us to improve access by safely

reducing overwhelming demand

for screening and surveillance

cystoscopy. It’s proven to be a

quadruple win: convenient and

preferred by our members, high

quality - reliable results, cost

effective for the organization,

and a sustainable way to improve

the wellbeing of our healthcare

teams,” Dr Loo said.

Kaiser Permanente is

the largest integrated

healthcare provider in the

US, serving 12.6 million

members, which equates

to approximately 3.7% of

the population in the USA.

It operates 39 hospitals,

more than 700 medical

offices, and employs

23,656 physicians and

65,000 nurses.

PACIFIC EDGE LIMITED INVESTOR UPDATE | OCTOBER 2022
6

NEW MARKET

ISRAELI

DISTRIBUTOR

FOR CXBLADDER

APPOINTED

CONFERENCES

STANDING ROOM ONLY AT

CXBLADDER SYMPOSIUM

A Pacific Edge symposium on the use of molecular

biomarkers in the detection and surveillance of bladder

cancer drew strong interest at the 87th American Urological

Association Southeastern Section (SESAUA) conference held

in Amelia Island, Florida last month.

The conference is one of the largest AUA Section Meetings.

It has a strong research focus and it offered time before the

conference program to hold a Principal Investigator meeting

for our STRATA clinical trial.

Additionally, Pacific Edge hosted a symposium in which

more than 100 urologists and urological experts participated.

Many were left standing for the keynote address from Dr.

Sia Daneshmand, Professor of Urology and Director of Clinical

Research at the Keck School of Medicine, and the discussion

that followed..

Pacific Edge VP of Medical Affairs, Dr Tamer Aboushwareb,

who led the symposium, said he was delighted with the

interest in Cxbladder at the conference.

“We were thrilled to see so many attendees at the

symposium showing great interest in the utility of Cxbladder.

Many more physicians identified the utility of the tests and

showed interest in using them in their patient populations; they

will all be followed up by Pacific Edge’s sales team,” he said.

At the conference, alongside the symposium, Pacific Edge

led a Principal Investigator meeting (IM) for the DRIVE study

– which is focused on Cxbladder Detect

+

validation across

multiple Veterans Administration sites.

The team also held multiple meetings with key opinion

leaders from the SESAUA with many continuing or starting the

use of Cxbladder in their respective organizations.

As Pacific Edge looks to develop Ex-

US commercial activity from Pacific

Edge Diagnostics USA (PEDUSA),

ProGenetics in Israel is the first

distributor with the resources and

expertise to join our distributor

network. The Tel Aviv-based

company has been awarded exclusive

sales and marketing rights in Israel

and will add Cxbladder to its broad

portfolio of the cancer diagnostic

tools it distributes. These tests span

tests for breast, prostate, ovarian, and

colon cancers among several others.

David Sosa, Pacific Edge’s VP

Market Access & Reimbursement

says: “We are delighted to be working

with a company that has such a

strong record of launching high-value

lab developed tests and working

with local healthcare plans to achieve

reimbursement. ProGenetics will drive

the integration of Cxbladder into

local standards of care leveraging its

strong relationships with clinicians,

and Pacific Edge’s growing body of

clinical evidence.”

Initially, the tests will be paid for

by patients on the recommendation

of their clinicians. Patient samples

will be collected using Pacific Edge’s

Patient In-Home Sampling System

and will be processed at our US

laboratory in Hershey Pennsylvania.

PEDUSA will support ProGenetics

with its Medical Affairs team and

provide training in sample collection

and logistics.

PACIFIC EDGE LIMITED INVESTOR UPDATE | APRIL 2023
7

RESEARCH AND INNOVATION

NEW STUDY TO VALIDATE CXBLADDER WITH

MICROHEMATURIA

Pacific Edge is launching a new study to demonstrate the validity of its new test, Cxbladder Detect

+

,

in detecting urothelial cancer in patients presenting with microhematuria.

The new study is microDRIVE - Detection and Risk Stratification in Veterans Presenting with microhematuria.

Microhematuria is a presentation of blood in urine that is not detectable with the naked eye. It is often found

in routine testing rather than the result of examinations related to symptoms that are potentially indicative of

bladder cancer.

MicroDRIVE will compare the performance of Detect

+

against the current gold-standard for the detection of

urothelial cancer, diagnostic cystoscopy and pathology. It runs alongside the existing DRIVE study with the VA.

The study is seeking to recruit up to 1,000 veterans and is projected to start recruitment towards the end of 2023,

with the aim of recruiting the last patient in the second quarter of 2024.

ONGOING STUDY PROGRAM ENROLLED SITES

AND LOCATIONS

PROGRESS AND TARGETS*

STRATA

(Safe Testing of Risk for Asymptomatic

Microhematuria)

11/13

USA and Canada

-

Enr

olment total is 468, including 122 ‘low risk’

subjects (with 400 and 105 of these subjects

eligible, respectively) that are the focus of the study

-

T

arget ~600 subjects, including 120 low risk subjects

randomized to test arm

-

Las

t patient in Q2 2023

-

F

ollow up until Q2 2024

DRIVE

(Detection and Risk Stratification in

Veterans Presenting with Hematuria)

8/11 (VA)

USA

-

Enr

olment total is 551

-

T

arget (Q2 2025) ~700 patients

-

Last patient in: Q3 2023

-Follow up: until Q3 2025

microDRIVE

(Detection and Risk Stratification in

Veterans Presenting with microhematuria)

0/0

USA

-

Pr

ojected to start recruitment Sep/Oct 2023

-

T

arget is 1000 patients

-

Las

t patient in: March/April 2024

AUSSIE

(Australian Urologic risk Stratification of

patients with hematuria)

1/1

Australia

-

C

ontract fully executed Mar 2023

-

Enrolment due to start in Q2 2023

-

Las

t patient in: Q2 2025

DEDUCT

(Detection of Disease in the Upper Tract)

-Now to be transferred to an investigator-initiated

study

LOBSTER

(Longitudinal Bladder Cancer Study for

Tumor Recurrence)

3/11

-

T

hree sites are open and another 8 are at pre-

activation. Enrolment is now 63 patients

-

Each site will enroll 100 patients within 12 months

and follow up for another 12 months

MONSTER

(Monitoring

Study of Post-Treatment

Effectiveness for Residual Disease)

0/1

New Zealand

-

Finalizing pr

otocol documentation and commenced

engagement with ethics committee

-

Busines

s case for this study currently in

development by R&D

*Dates are calendar year not financial years

Analytical Validity: Develop a test that is repeatable in the lab for a given indication and population.

Clinical Validity: Make sure the test works in the same way on an independent eligible population for the given indication.

Clinical Utility: Put the test in the hands of a physician to establish that it can usefully change patient management within

the context of care for the defined population and indication.

Visit the Pacific Edge website to learn more about the strategic rationale for our studies.

PACIFIC EDGE LIMITED INVESTOR UPDATE | APRIL 2023
8

RESEARCH AND INNOVATION

STUDY ADDS SUPPORT FOR

CXBLADDER MONITOR USE IN

CANCER SURVEILLANCE

ASIA PACIFIC

NEW APAC LEADER

Glen Costin has been appointed

into the new role of President

Asia Pacific (APAC) to realize

the significant potential for the

company’s genomic Cxbladder tests

in the region.

Glen is charged with building on

our presence in Australia and New

Zealand into the broader APAC

region. He will drive the strategic

and operational direction in the

region, which boasts an estimated

total addressable market for the

company’s Cxbladder diagnostic

tests of US$2.2 billion.

8


For the last eight years, at the

helm of his own company MDL Asia,

Glen has assisted small and medium

sized medical, diagnostics and life

science companies to expand in the

Asia Pacific. Over that period, he

assisted his clients to grow annual

revenues by US$20 million to US$30

million per year. Prior to that he

held senior roles with biotechnology

research company Abcam,

laboratory equipment supplier Bio-

Rad Laboratories and BD (Becton

Dickinson).

He brings to Pacific Edge a

strong regional network in APAC, a

strong commercial background, a

track record of success in business

development and in bringing new

technology to market. He holds a BSc

from Macquarie University and an

MBA from the Macquarie Graduate

School of Management. He started at

Pacific Edge on March 27th and will

report to Dr Meintjes.

8

Pacific Edge estimates.

6

The study, “Cxbladder Monitor testing to reduce cystoscopy frequency in patients with bladder

cancer”, was completed with no involvement or financial support from PEDUSA

7

Six of the 66 CxbM negative patients did not return for a follow up cystoscopy, four elected to

undergo a further CxbM test rather than a cystoscopy and the remaining four patients either stopped

surveillance or died of unrelated causes. Nine of the 24 patients that tested Cxbladder Monitor

positive and then had an immediate clinical evaluation and cystoscopy were found to have cancer

including one patient that had cancer in the upper tract.

New and independent

6

research supporting the clinical utility

of the company’s genomic biomarker test Cxbladder Monitor

in the surveillance for bladder cancer recurrence is to be

published in the prestigious journal Urologic Oncology.

The study undertaken at the University of California San

Francisco (UCSF) and the University of Michigan examined

whether a negative Cxbladder Monitor test could safely

postpone a patient’s next scheduled cystoscopy, the current

‘gold standard’ for bladder cancer surveillance.

The study covered a small sample of US-based patients

under surveillance for bladder cancer recurrence during the

COVID pandemic lockdown. The patients - under the virtual

supervision of their clinicians - opted to use Cxbladder Monitor

leveraging Pacific Edge’s Patient In-Home Sampling System

(PIHSS) as a first step to overcome pandemic-related limits on

clinical evaluation slots and the risks of COVID infection during

travel to and from appointments.

Of the sample, 66 patients tested negative for Cxbladder

Monitor. Of those, 52 patients underwent a follow up

cystoscopy, and all were tumor free – a result that supports

the growing portfolio of evidence that Cxbladder Monitor can

safely reduce surveillance cystoscopies without compromising

cancer detection.

7

Meanwhile, a patient satisfaction survey of

those who took the Cxbladder Monitor test at UCSF revealed

strong patient acceptance for the test and the PIHSS.

Vice President of Medical Affairs Dr Tamer Aboushwareb

said: “The sample size and the difficulties the researchers faced

in following up all those patients that tested Cxbladder Monitor

negative represent obvious limitations to the current study, but

the results represent an exciting incremental addition to the

evidence supporting the clinical utility of Cxbladder Monitor in

safely reducing the frequency of surveillance cystoscopy.”

University of California San Francisco

PACIFIC EDGE PEOPLE
JOINING THE COMPANY WITH THE MOST DATA

Dr Daniel Shoskes joined Pacific Edge Diagnostics USA at the end of October as Senior Medical Director. In

his role as part of Pacific Edge’s Medical Affairs team Daniel will be focused on our education mission.

He is also tasked with encouraging research into Cxbladder through the development of a program to support

investigator-initiated trials as well as new registries to accumulate real world data on the use of Cxbladder.

Daniel joins Pacific Edge as a well-known member of the urological community with a wealth of experience. He

has worked as an academic Urologist at UCLA and the Cleveland Clinic and has held several roles at the American

Urological Association (AUA), including the presidency of two sub-specialty societies, and directorship of the AUA

Board Review Course. Daniel has also served on both the AUA Research and Education Councils.

What brings you to Pacific Edge?

Pacific Edge VP Medical Affairs Dr Tamer Aboushwareb was a colleague

at Exact Sciences where we worked on prostate cancer diagnostic tests,

and I knew we worked together well. Additionally, it was attractive to join

the company with the most data to date and a growing list of new studies

poised to generate evidence that should be compelling to the committees

setting clinical guidelines. .

What is the most compelling evidence in your view supporting the use of

Cxbladder?

I think there are two distinct and complementary perspectives supporting

the use of Cxbladder. From the patient’s point of view there is convenience

and reduction of anxiety. The ability to do a home test prior to scheduling

an appointment or procedure can save time and cost.

With a negative Cxbladder test there is confidence in avoiding an

uncomfortable procedure. From the Urologist point of view there is added

confidence in getting the diagnosis right and only escalating to more

invasive testing if it is warranted.

Not every hematuria patient presents with symptoms where the course of

action is clearly outlined by the guidelines. For example, there are patients

with benign causes of hematuria that don’t warrant treatment but whose

recurring hematuria technically leads to repeated cystoscopy. There are

patients whose cystoscopy is very challenging with the view obscured by

inflammation, bladder abnormalities, and other pathologies. In these cases,

adding Cxbladder to the diagnostic armamentarium can give confidence in

the diagnosis and simplify care.

What criteria will you use to judge success in your role at Pacific Edge?

In terms of new initiatives, I’m excited about our Investigator Initiated Trials

program and its ability to produce high quality publications that will further

the evidence for efficacy and utility of our products. On an incremental

level, I hope to refine our messaging of the value proposition for using

Cxbladder for Urologists and make it clearer which patient scenarios will

most benefit from adding Cxbladder to the workflow.

What will make the greatest difference to driving the adoption of

Cxbladder?

Being in clinical guidelines goes a long way to widespread clinical adoption

as well as robust insurance coverage (in the USA). I am confident that the

new clinical trials now in design and being carried out at Pacific Edge are

set up to deliver the kind of compelling validity and utility data that would

lead to guidelines adoption.

What is the newest addition to your Spotify playlist and why?

I deleted my Spotify account in response to their financial support of anti-

vaccine podcasts, but music is an important part of my life, both listening

and performing. While most of my performance has been in Renaissance

and Baroque music, I have recently started playing Medieval music on the

Gittern, a plucked instrument popular in the 12th to 15th centuries.

PACIFIC EDGE LIMITED INVESTOR UPDATE | APRIL 2023

9

DR DANIEL SHOSKES


Senior Medical Director

MD, MSc, FRCS (C)

1994 – 2000:

Urologist.

UCLA

2000 – 2005:

Urologist and Director of

Kidney Transplant Program.

Cleveland Clinic Florida

2005 – 2021:

Professor of Urology

, Director,

The Novick Centre for Clinical

and Translational Research;

Director The Center for Men’s

Health. Cleveland Clinic

2021 – 2022:

Medical Director Medical

Affairs.

Exact Sciences

ABOUT US
Pacific Edge Limited (NZX/ASX: PEB) is a

global cancer diagnostics company leading

the way in the development and

commercialization of bladder cancer

diagnostic and prognostic tests for patients

presenting with hematuria or surveillance of

recurrent disease. Headquartered in Dunedin,

New Zealand, the company provides its suite

of Cxbladder tests globally through its wholly

owned, and CLIA certified, laboratories in New

Zealand and the USA.

VISIT US ONLINE:

www.pacificedgedx.com

www.cxbladder.com

FOLLOW US ON SOCIAL MEDIA:

www.facebook.com/PacificEdgeLtd

www.facebook.com/Cxbladder

www.twitter.com/PacificEdgeLtd

www.twitter.com/Cxbladder

www.linkedin.com/company/pacific-edge-ltd

CONTACT US:

Centre for Innovation

87 St David Street

PO Box 56

Dunedin 9016, New Zealandd

T: +64 3 479 5800

E: investors@pacificedge.co.nz

Data sourced from publicly available filings. Our datasets may not be complete. Automated analysis can produce errors. If you believe any data on this page is incorrect, please contact us at hello@nzxplorer.co.nz. For informational purposes only. Not investment advice.