TRUSCREEN GROUP LIMITED logo

Updated Investor Presentation

Investor Presentation27 February 2024TRUIndustrials

TruScreen Group Ltd
NZX|ASX: TRU

FY2024

Accelerating growth

February 2024

Beata Edling

CEO TruScreen

This Presentation
Screening for Cervical Cancer,

world’s priority in 2024

About TruScreen technology

Key achievements YTD financial year

2024

China, our biggest market and growth

potential

Accelerating sales growth in financial

year 2024

Key takeaways

2

About
TruScreen

technology

4
WORLD CLASS technology made simple

Real-time, AI-enabled, primary cervical cancer screening

device for detection of pre-cancerous and cancerous cervical

tissue

►Optical and electrical measurements painlessly detect abnormalities in

cervical tissue

►A Single Use Sensor (SUS) used for each exam, preventing cross-

contamination

►AI-enabled algorithm provides Normal/Abnormal

result immediately

►No invasive cervical cell or tissue collection

►EU certified (CE Mark) and ISO 13485 compliant

class IIa medical device

5
20 Years of Clinical Studies with 42,000 Patients*

0

5000

10000

15000

20000

25000

30000

35000

40000

45000

AustraliaAustralia

China- Wang ling

China- Zhang Wei

Poland

China- Lu

Korea

China- Zhang Wei

China- Feng

Korea

China- Cui Ying Ying

China- He Xiu Kui

China-Li Xia

China- Li Xi

China- Weihong Li

Russia-Sukhikh

Poland

Russia-Firichenko

Turkey

China-Shuai Ping

China- Zhang Wei

China- Shuyu Long

Iran

Bulgaria

Turkey

Indonesia

China- Du x

India

China- Li pei

Mexico

India

China

Mexico

Australia

China -COGA

China - Jinghe Land

China, Yu Ma

YingTing Wei et al

Poland, Suchonska et al

Jessica N. Vet et al

Fei Chen at all

2003 2004 2008 2008 2008 2009 2009 2009 2009 2010 2010 2010 2011 2011 2011 2011 2011 2011 2011 2012 2013 2013 2013 2013 2015 2015 2015 2015 2016 2016 2018 2011 2018 2018 2019 2019 2020 2021 2021 2022 2022

*Cumulative number of women subjects in independent clinical studies

Moving from multi-step, expensive screening to Point-of-Care Solution
6

TruScreen transformation of cervical cancer screening

Specimen

Collection

Label, Packaging

and Transport

Slide PreparationFixationStaining

Microscopic

Examination

InterpretationReporting

Communication

of Results

Perform TestObtain Result

Advantages

• Integration into healthcare systems: hospitals, clinics

• Immediate management of positive results with

streamlined patient flow efficiency

• Better patient experience

• Cost saving, time saving

• More efficient utilization of healthcare resources

2 - 3 weeks

Current cervical screening process is multi-step, error prone, people dependant, uncomfortable for a woman,

slow, expensive and inefficient (loss in follow up)

10 min

Trusted Clinical Performance
High sensitivity

in detecting

CIN2+*

High specificity

in detecting

CIN2+*

Extensive body

of clinical

evidence

TruScreen

®

has been found

to be as sensitive in

detecting CIN2+ as

cytology**

4

TruScreen

®

has been

found to be more specific

in detecting CIN2+ as

cytology**

4

Over 40,000 women in

clinical trials to date***

* CIN2: A cervical biopsy finding that means moderately abnormal cells were found on the surface of the cervix.

CIN2 is usually caused by infection with certain types of human papillomavirus (HPV). Source: NIH, www.cancer.gov

** Data from large observational study, Cytology used was ThinPrep

*** Total number of subjects across published and unpublished clinical studies in English, data from TruScreen device generation I and II

7

7

Cervical cancer
elimination

WHO priority in 2024

Cervical cancer is the fourth
most common cancer in

women globally

Globally, 604 000 new cases and 342 000

deaths were recorded in 2020

About 90% of these deaths occurred in

low- and middle-income countries

The highest rates are inAfrica, Central

America and South-East Asia.

20% of children who lose their mother to

cancer do so due to cervical cancer.

9

Source: Human papillomavirus and cancer (who.int)

10
Cervical Cancer Is A Global Public Health Issue

1


604,000new cases and 342,000deaths a year


Most diagnoses occur at working age (35-44)


90% of new cases and deaths occur in LMICs

Fourth most common cancer in

women worldwide, 1BN+ women

of screening age in LMICs

90% coverage of

HPV Vaccination

girls (by 15 years of age)

70% coverage of screening

& 90%treatment

of precancerous lesions

Management of

90% of cases

of invasive cancer

The World Health

Organisation (WHO)

has set a target to

eliminate cervical

cancer by the end of the

century.

1

Cervical cancer (who.int)

Screening most important for next 3 decades
11

In 2020, the CCEMC published the

modelling of the CC elimination as

well as commented on the status in

Lower-and Middle-Income

Countries (LMICs).

Compared to the status quo, by

2030, vaccination alone would have

minimal impact on death rate

Scaling up twice-lifetime screening

and cancer treatment would reduce

death rate by 34%averting

300 000–400 000 deaths by 2030.

Source:

WHO Cervical Cancer Elimination Modelling Consortium (CCEMC), 2020

Screening needs to accelerate, APEC example
12

1

APEC Economic Status Report: Cervical Elimination in the APAC region

March 2023

13
Effective co-invest model with global distribution

Distributors

End-users

1

Cervical cancer (who.int)

Lean headquarters

Recurring revenue

stream from consumable

SUS

Intellectual Property

Service &

manufacturing


Local knowledge

and influence


End-user

management


Public and private hospitals

and clinics


Public health initiatives


Governments & Non-

Government Organisations

14
European Union:

CE Mark

ISO 13485

Registered with:

TGA, Australia

MHRA, UK

NMPA, China

SFDA, Saudi Arabia

Roszdravnadzor, Russia

COFEPRIS, Mexico

TruScreen’s presence and markets*

Mexico

10.7 M

China

119.1 M

Russia

13.4 M

Africa

73.8 M

CE

Europe

6.7 M

Current Markets

Targeting commercial rollout

Markets under review

China

119.1 M

CE

Europe

6.7 M

India

100.1 M

Indonesia

23.1 M

China

119 M

Saudi

3.6 M

CE

Europe

6.7 M

Vietnam

8.3 M

* Number of eligible women to undergo cervical cancer screening

Key
achievements

Sales growth

FY2024

China:
TruScreen’s largest market and

growth opportunity

Remains TruScreen’s top market

●High government support for cervical cancer

screening

●Made in China TruScreenstatus from 2021 –

preferred market access in China

FY 2024 Market Progress

●Record sales of SUS: YTD FY24 results exceeded

total of FY23

●National Health Check Program to commence:

10000 women to be screened in 10 major

hospitals, over 3 years

●Roll out of COGA Blue Book & CSCCP guidelines

China market, USD M, PBI Market Research 2020
17

*©2020 Precision Business Insights

0.0

500.0

1000.0

1500.0

2000.0

2500.0

3000.0

3500.0

4000.0

2015 (A)2016 (A)2017 (A)2018 (A)2019 (A)2020 (F)2021 (F)2022 (F)2023 (F)2024 (F)2025 (F)2026 (F)

China Cervical Cancer Screening Market Historical and

Forecast, USD Million*

PAP Smear testsHPV testsLBC testsOthers M USD

0.0%

2.0%

4.0%

6.0%

8.0%

10.0%

12.0%

14.0%

16.0%

CAGR (USD Million), By Test Type,

2015 – 2026*

PAP Smear testsHPV testsLBC testsOthers

China and APAC market, recent growth exceeded
expectations

18

HPV Test Market Revenue (Million USD) and Growth Rate

(2018-2028)

Business Market Insights

June 2023:

The Asia Pacific CIN & HR-HPV

treatment market is expected to grow

from US$ 2,738.94 million in 2023 to

US$ 3,949.99 million by 2028.

It is estimated to grow at a CAGR of

7.6% from 2023 to 2028.

19
December 2023, pipeline

•72 hospitals have obtained

OBGYN department acceptance,

awaiting hospital approval

•25 hospitals have received

TruScreen approval, awaiting

tender

•12 tenders won, awaiting hospital

installation

China, TruScreen FY2024 installations

By end of FY 2024

~100 devices

installed and in use

12

25

72

China, potential for SUS pull through growth
20

The devices in China

currently have an average pull

through of 106 SUS per device

per month, 24% growth in FY24

the potential average pull-

through of SUS exceeds 290

per month

Key accounts reach 500+ SUS

pull through

A B C D E F

Vietnam
Focus market with renewed focus on public hospital rollout

The Market Opportunity

●24m women of screening Age

*

,booming economy and

middle class

●No centralised screening programs

FY2024 Market Progress

●Ministry Of Health (MOH) has listed TruScreen on the

NationalTechnical List of approved technologies

●New legislation in March 2024 to considerably shorten

approval process, accelerating new installations

●2 main hospitals received MOH approval

Pipeline

●15 hospitals ready to apply to local authorities when new

legislation commences

●Strong local authorities support

*©2020 Precision Business Insights

Zimbabwe
●Very successful Government screening program in

Masvingo province, 14 000 women screened to date,

●Two tenders won in 2023

Saudi Arabia

●Commercial rollout commenced in FY24

●Most private health insurers are reimbursing

TruScreen procedure

Mexico

●COFEPRIS approval granted access to public health

sector

Poland

●TruScreen won top award in a Mother and Child

Institute challenge for healthcare companies,

granting implementation in the largest public

hospital network for women health in Poland

FY24 Other Markets

Top achievements FY2024
Sales and Revenue, Q1-Q3 FY2024:

SUS sales exceeded total of FY2023, 22%

growth YOY

Device sales 40% growth YOY

China, major contributor with immense

market growth opportunity

23

Achievements:

China: COGA Blue Book and CSCCP Guideline

entries

Vietnam: MOH inclusion in the National Technical

List

Saudi Arabia: commercial roll out and private health

insurers listing

Zimbabwe: continues NAC screening program,

TruScreen wins tender

Poland: TruScreen wins top award for

implementation in the largest public hospital

network for women health in Poland

Mexico: TruScreen receives Cofepris approval and

access to public health sector

Outlook strategy
and goals

FY2024-2025

Improve
operations

•Enhance marketing

•Reduce cost of goods

(COGS)

Strengthen

partnerships

•Enhance relationships

•Talk economics

•Provide solutions

Drive Growth

•Double down on

performance

•Diversify deliberately

FY2024- FY2025 Strategy

Focus on 3 strategic drivers

Strong together

25

Our Short Term Goals
26

Maximise

Seize the COGA

Blue Book &

CSCCP national

guideline window to

grow sales in China

Expand

Successfully expand

markets in

Zimbabwe, Saudi

Arabia, and Vietnam

Grow

Grow commercial

presence in Africa,

Middle East, Central

and Eastern Europe

Improve

Improve the gross

margin by reducing

COGS

Expansion and adoption of
technology in the screening cervical

cancer guidelines in target markets

Development of technology toward

diagnostics and treatment of

cancers

27

Long Term

Goals

28
*This is not a forecast of performance or expected results

0

50000

100000

150000

200000

250000

0

50

100

150

200

250

300

350

Mar '19Mar '20Mar '21Mar '22Mar '23Mar '24* Mar '25*

FY2019 - FY2023, actuals

FY2024 - FY025, projections*

Installed DevicesSUS Sales

we are here

Device installations and SUS sales FY2019- FY2025

Key take-aways
Sales growth from SUS

consumable usage driven by

increased device installed & use

China remains the biggest market

with huge opportunity

Global growth commenced

Transformative technology of the

immediate future

Cervical cancer elimination:

international priority in 2024

©
www.truscreen.com

Contact us
for more

information

31

Dr Beata Edling

CEO

M - +61 419 569 993

E – beataedling@truscreen.com

TruScreen

36 Bradfield Road, CSIRO

Lindfield West NSW 2070

Australia

www.truscreen.com

Guy Robertson

Chief Financial Officer

M – +61 407 983 270

E – guyrobertson@truscreen.com

TruScreen

36 Bradfield Road, CSIRO

Lindfield West NSW 2070

Australia

www.truscreen.com

@TruscreenGroupLtd

@TruscreenGroupLimited

32
Disclaimers

This presentation has been prepared by TruScreen Group Limited (the “Company”) and is dated 25 August2023. This presentation contains summary

information about the Company and its activities which is current as at the date of this presentation. The information in this presentation is of a general

nature and does not purport to be complete nor does it contain all the information which a prospective investor may require in evaluating a possible

investment in the Company. This presentation should be read in conjunction with the Company’s annual report, market releases and other periodic and

continuous disclosure announcements, which are available at www.nzx.com. This presentation does not constitute an offer, advertisement or invitation in

any place in which,or to any person to whom,it would not be lawful to make such an offer, advertisementor invitation.

Not financial product advice

This presentation is for information purposes only and is not financial or investment advice or a recommendation to acquire the Company’s securities, and

has been prepared without taking into account the objectives, financial situation or needs of prospective investors. Before making an investment decision,

prospective investors should consider the appropriateness of the information having regard to their own objectives, financial situation and needs and

consulta financialadviser, solicitor, accountant or other professional adviser if necessary.

Past performance

Any past performance information given in this presentation is given for illustrative purposes only and should not be relied upon as (and is not) an indication

of future performance.No representations or warranties are made as to the accuracyor completenessof such information.

Future performance

This presentation includes certain “forward-looking statements” about the Company and the environment in which the Company operates. Forward-

looking information is inherently uncertain and subject to contingencies, known and unknown risks and uncertainties and other factors, many of which are

outside of the Company’s control, and may involve significant elements of subjective judgement and assumptions as to future events which may or may not

be correct. A number of important factors could cause actual results or performance to differ materially from any forward-looking statements. No

assurance can be given that actual outcomes or performance will not materially differ from the forward-looking statements. The forward-looking

statements are based on information available to the Company as at the date of this presentation. Except as required by law or regulation (including the

Listing Rules), the Company undertakes no obligation to provide any additional or updated information whether as a result of new information, future

events or results or otherwise.

33
References

1.WHO, HPV and Cervical Cancer Fact sheet, 11 November 2020, https://www.who.int/news-

room/fact-sheets/detail/human-papillomavirus-(hpv)-and-cervical-cancer

2.WHO Cervical Cancer Elimination Modelling Consortium (CCEMC), 2020

3.Human papillomavirus and cancer (who.int)

4.Wei, Y., Wang, W., Cheng, M., Hong, Z., Gu, L., Niu, J., Di, W., & Qiu, L. (2021). Clinical

evaluation of a real-time optoelectronic device in cervical cancer screening.European journal

of obstetrics, gynecology, and reproductive biology,266, 182–186.

https://doi.org/10.1016/j.ejogrb.2021.09.027.

5.Vet, J. N., Haindl, J. P., Velasquez, C., Parker, L. J., Burns, M. I., Morrell, S., & Campion, M.

J.. (2022). A Performance Evaluation of an Optoelectronic Cervical Screening Device in

Comparison to Cytology and HPV DNA Testing.European Journal of Gynaecological

Oncology,43(2), 213. https://doi.org/10.31083/j.ejgo4302027

6.Central Intelligence Agency, The World Fact Book, CHINA, People and Society, Female ages

25-64 Years, visited 28 August 2020, https://www.cia.gov/library/publications/the-world-

factbook/geos/ch.html

7.Central Intelligence Agency, The World Fact Book, VIETNAM, People and Society, Female

ages 25-64 Years, visited 28 August 2020, https://www.cia.gov/library/publications/the-world-

factbook/geos/vm.html

A world

without

cervical

cancer.

Data sourced from publicly available filings. Our datasets may not be complete. Automated analysis can produce errors. If you believe any data on this page is incorrect, please contact us at hello@nzxplorer.co.nz. For informational purposes only. Not investment advice.