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Annual Report 2025

Annual Report29 June 2025PEBHealthcare

ANNUAL REPORT
FOR THE YEAR ENDED 31 MARCH 2025

Pacific Edge Limited is a global cancer diagnostics company
leading the way in the development and commercialization of

bladder cancer diagnostic and prognostic tests for patients

presenting with hematuria for surveillance of recurrent disease.

Headquartered in Dunedin, New Zealand, with shares listed on

the NZX and the ASX under the ticker code PEB, the company

provides its suite of Cxbladder tests globally through its

wholly owned, and CLIA certified, laboratories in New Zealand

and the USA.

2

This report provides a summary review of Pacific
Edge’s operational and financial performance for the

year to 31 March 2025. It should be read in conjunction

with the company’s financial statements on pages

69 to 104 of this report. Throughout this report we

have focused on what we believe matters most to

our stakeholders and our business. Our aim is to

provide easily understood, transparent and engaging

disclosures for our shareholders that describe our

business, what we do and why we do it.

The information in this report has been compiled in

accordance with relevant law, rules, and corporate

governance recommendations for investor reporting.

Financial information has been prepared in accordance

with appropriate accounting standards and the

consolidated financial statements have been audited

by PwC New Zealand.

This report, including the commentary, financial

statements and information required by statute were

approved by the Pacific Edge Board on 30 June 2025.

An electronic version of this report is available on the

investor section of our website: www.pacificedgedx.com

Chris Gallaher Tony Barclay

Chairman Chair of the Audit

and Risk Committee

Highlights 4

Chair and CEO reports 6

Strategic overview and success 12

Sustainability 22

Board and management 42

Governance 46

Risk analysis 57

Remuneration 63

Financial statements 69

Auditors report 105

Statutory information 110

Directory 114

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

3

FY 2025 FINANCIAL AND OPERATING HIGHLIGHTS
FINANCIAL PERFORMANCE

2



1H


2H

GLOBAL COMMERCIAL TEST VOLUMES

0

5,000

10,000

15,000

20,000

25,000

30,000

35,000

TESTS



1H


2H

GLOBAL TOTAL TEST VOLUMES (TLT

1

)

0

5,000

10,000

15,000

20,000

25,000

30,000

35,000

TESTS

FY 25FY 24

$21.8M

OPERATING REVENUE


8.6%

US$594

FY 25 AVERAGE US SALES PRICE


1.7% ON FY 24

$29.9M

NET LOSS AFTER TAX


1.4%

$22.6M

CASH, CASH EQUIVALENTS

AND SHORT-TERM DEPOSITS

AT 31 MARCH 2025

406

Q4 25 TESTS/US SALES FTE


6.4% ON Q4 24

$16.1M

NEW EQUITY RAISED

IN MAY 2025

3


1

Total Laboratory Throughput (TLT) includes commercial, pre-commercial and clinical studies testing

2

All comparisons are to the same period of the prior financial year unless otherwise stated

3

Subject to shareholder approval to be sought at the 2025 Annual Shareholders' Meeting

23,086

FY 22

11,950

11,136

32,633

14,393

18,240

28,894

14,669

14,225

FY 23

31,565

16,645

14,920

26,691

FY 23

12,422

14,269

19,196

FY 22

9,192

10,004

27,347

15,401

11,946

FY 24

24,642

12,325

12,317

FY 25

A RESILIENT PERFORMANCE AMID MEDICARE UNCERTAINTY

We have delivered an improved sales force performance, operating efficiencies and cash

collection gains, positioning the company for accelerated growth as we work towards

regaining Medicare coverage of our tests.

4

FY 2025 FINANCIAL AND OPERATING HIGHLIGHTS
TEST VOLUMES BY TYPE (TLT)



CXBLADDER DETECT


CXBLADDER MONITOR


CXBLADDER TRIAGE



APAC


AMERICAS



1H


2H

PACIFIC EDGE OPERATING REVENUE

REGIONAL REVENUE CONTRIBUTION

$0

$5,000

$10,000

$15,000

$20,000

$25,000

$30,000

$(000)

FY 25FY 24

$19,916

$10,909

$8,707

$23,907

$10,812

$13,095

$21,846

$10,887

$10,959

FY 22

$11,445

$6,067

$5,378

FY 25

49%

19%

32%

FY 24

57%

22%

21%

FY 23

92%

8%

6%

FY 25FY 24

94%

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

5

Dear Shareholders
Pacific Edge delivered a resilient financial

result for the year ended March 2025 and

achieved two company defining milestones.

Our Cxbladder Triage test received a ‘Grade A’

1


evidence rating from the American Urological

Association (AUA) in its new microhematuria

guidelines — the highest endorsement available

given the available evidence. Meanwhile, the US

Centers for Medicare & Medicaid Services (CMS)

proposed a draft price of US$1,018.44 for our

Cxbladder Triage Plus test, which represents a

meaningful increase over the current US$760

pricing.

The first of these achievements, as Peter outlines

in his Chief Executive's Report, positions Pacific

Edge to overcome the primary disappointment

for the year — the adverse ‘Genetic Testing for

Oncology: Specific Tests (L39365)’ Local Coverage

Determination by Medicare Administrative

Contractor Novitas that ended Medicare coverage

of our tests. It has entrenched our first mover

advantage, extended the moat around our

business and also delivered a shift in clinical

sentiment towards the adoption of our tests both

in the US and further afield. The second of these

achievements — favorable pricing of Triage Plus

— positions Pacific Edge for increased revenue

growth and a faster path to profitability in the US

once Medicare coverage is reinstated.

Meanwhile in the face of the uncertainty for

most of the FY25 year over continued Medicare

coverage of our tests, we delivered enhancements

in sales performance, operational efficiency, and

improved cash collection, making us leaner and

more productive organization. We have also grown

the volume of tests supplied to non-Medicare

healthcare payers.

Directors are encouraged to see so many

shareholders share our strategic outlook, as

demonstrated by the strong support we received

for the first stage of the ~$20 million capital raise

launched on the same day we announced our

FY 25 results (see below). Our focus is now on

making good on that potential.

FINANCIAL RESULTS

Operating revenue of $21.8 million was down 8.6%

from $23.9 million in FY 24, but steady against 1H

25 reflecting the ongoing Medicare uncertainty

and the reduced reach of the sales team following

the restructuring at the start of 2H 24. FY 25 TLT

of 28,894 tests was down 11.5% on the 32,633 tests

in FY 24, but 2H 25 volume was steady against 1H

25. Commercial test volumes were down 9.9% on

FY 24 to 24,642 tests, but steady against 1H 25.

However, since the LCD became effective, we have

seen its impact in reduced volumes.

Tests for Medicare and Medicare Advantage —

those affected by the LCD — represented 53%

of US commercial tests in FY 25 vs 58% in 1H 24.

This improvement reflects rising demand from

contracted payers such as the Southern California

Permanente Medical Group.

The Average Sales Price for US testing increased

to US$594 in FY 25 vs US$584 in FY 24 as

cash collection improvements were sustained.

Throughput per Sales FTE improved again to 405.6

tests in Q4 25 from 381.2 in Q4 24.

Tests per unique ordering clinician (our preferred

metric for measuring customer commitment to

Cxbladder) was 7.1 in Q4 25 compared to 6.7

in Q4 24 as we focused efforts on profitable

accounts and territories. The net loss after tax of

$29.9 million was steady on FY 24 (up 1.4%), with

reduced FY 25 revenue offset by the benefits of

cash conservation initiatives. Costs were higher

in 2H 25 led by the increased investment in

clinical research, the costs associated with the

commercialization of Triage Plus and an increase in

legal fees as we challenged the LCD.

CASHFLOW AND BALANCE SHEET

Cash and cash equivalents and short-term deposits

stood at $22.6 million at the end of March 2025,

down from $35.9 million at the end of September

2024. The 2H 25 cash burn of $13.4 million was

lower than the $14.3 million in 1H 25, but after

accounting for the higher cash expenditure in 1H 25

related to payments that cover a 12 month period,

the underlying cash burn was steady as operating

cash conservation initiatives continued to deliver.

CHAIRMAN’S REPORT

1

The AUA defines ‘Grade A’ evidence as evidence with a high certainty rating and notes evidence of this grade makes it "very confident that the true

effect lies close to that of the estimate of the effect"

GUIDELINE INCLUSION: A COMPANY DEFINING MILESTONE

6

As I mentioned we took steps to strengthen our balance
sheet in late May with the placement of $16 million in

new equity to investors and the planned launch of a ~$5

million Share Purchase Plan (SPP) for retail investors. We

are undertaking this capital raising, which is subject to

shareholder approval

2

, because the guideline inclusion

allowed the company to view the non-coverage

determination differently, giving us the option to build on

the commercial momentum we have already established,

including our plans to regain Medicare coverage.

GOVERNANCE

The Board at Pacific Edge has seen some changes over

the last year. Mark Green stepped aside after our annual

meeting in September 2024, and we resolved not to

replace him in line with our capital preservation efforts.

As disclosed in June, I have accepted the Board invitation

to postpone my planned retirement from Pacific Edge

and remain as Chair of the company to provide the

stability and continuity the company needs at present.

Consequently, I intend to stand for re-election at the

company's Annual Shareholders' Meeting.

OUTLOOK

In the short term we expect to see a reduction in US

test volumes and revenue reflecting the impact of the

LCD. However, in the medium to long-term we see

a resumption of growth as we increasingly change

physician behavior off the back of guidelines inclusion.

Supported by the new capital we are raising from

shareholders, we can now look forward to a time when

our tests are covered by Medicare.

I look forward to seeing you all at our Annual

Shareholders’ Meeting in early August to consider these

matters and the capital raising.

With my warm regards,

Chris Gallaher

Chairman

“... the guideline

inclusion allowed

the company to view

the non-coverage

determination

differently..."

2

Shareholder approval is required to settle the Placement (i.e., for payment for, and

allotment of, the new shares offered under the Placement) given the Placement

exceeds Pacific Edge's placement capacity (15% of Pacific Edge's current shares on

issue) and due to Related Party participation. The Placement is also conditional on all

necessary regulatory approvals. In this regard, the company intends to seek a waiver

from NZX Listing Rule 4.19.1 to permit the allotment of shares under the Placement

after shareholder approval is obtained. The Placement offer closed on 30 May 2025

for the purposes of clause 21(1)(b)(ii) of Schedule 8 to the Financial Markets Conduct

Regulations 2014.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

7

Dear Shareholders
Pacific Edge can look back on FY 25 as the

year it definitively established itself as the

first mover in non-invasive bladder cancer

diagnostics and secured all the advantages

that come with that position.

The American Urological Association’s (AUA)

inclusion of Cxbladder Triage in the new

microhematuria guideline with a ‘Grade A’

evidence rating — the only biomarker to achieve

that evidentiary standard — has highlighted this

position and provides us the means to entrench

our leadership. Supported by the guideline, our

peer-reviewed clinical evidence, and the proceeds

from the ongoing ~$20 million capital raising, we

are seeking to advance the commercialization of

our tests in the US and further afield.

MEDICARE RE-COVERAGE

With the LCD becoming effective on 24 April

2025 — despite Pacific Edge undertaking vigorous

political advocacy efforts and pursuing potential

legal avenues — we have two paths forward.

The first is the definitive path to change the

non-coverage determination to a coverage

determination by submitting a reconsideration

request to Novitas with the AUA guideline and the

evidence that has previously not been reviewed

in the original determination. This includes the

groundbreaking STRATA study

1

on which the new

guideline was based. We lodged a reconsideration

request for Cxbladder Monitor in May 2025

supported by two new real-world studies out of

Australia. With these reconsideration requests in

place, the South Eastern Section of the American

Urological Association (SESAUA), and at least 15

urologists have asked Novitas to expedite review

of our Cxbladder Triage. Furthermore, the AUA has

sent in its own reconsideration request including

their guidelines, the STRATA paper and a reference

to real world evidence demonstrating the clinical

utility of Cxbladder presented to the AUA annual

meeting by Kaiser Permanente.

The second is to appeal claim denials through

the Medicare Appeals Process providing the AUA

guideline as evidence to an Administrative Law

Judge to reverse the claim denial. Our success is

not guaranteed, but guideline inclusion is typically

considered a much higher standard of evidence

than the 'medically reasonable and necessary'

standard required under the US Social Security Act.

We have meanwhile taken steps to mitigate

the uncertainty linked to L39365 by focusing

commercial operations on profitable territories,

non-Medicare revenue streams and selling the

clinical and economic value of Cxbladder. These

efforts have delivered tangible improvements in

the performance metrics we track for sales force

efficiency and customer stickiness.

Beyond the challenges of the new operating

environment and these new initiatives, our clinical

evidence program will continue to generate

published evidence for further reconsideration

requests or to embed them in guidelines.

Importantly, our DRIVE Study and STRATA

Concordance Study are on track for publication

later this year. The publication from the DRIVE

study will confirm the clinical utility of Triage

Plus for the same indication as Triage in the AUA

microhematuria guideline.

Recognizing that no new evidence has

been published that can be submitted for

reconsideration of Cxbladder Detect, we have

decided to discontinue the test in the US. Users

are being migrated to Triage, accelerating a

plan previously intended to coincide with the

commercial launch of Triage Plus.

Triage Plus is set to underpin the future of

the company as the sole test for hematuria

evaluation in the US, supported by strong

clinical endorsement and a compelling economic

profile. Triage Plus is currently available to select

customers under an early access program, and its

full commercial launch will follow the establishment

of reliable reimbursement. With the draft pricing

34% higher than our existing tests, the threshold

number of tests for an Account Executive to

achieve profitability lowers, enabling faster scaling

and a clearer path to long-term profitability.

CHIEF EXECUTIVE'S REPORT

1

Lotan et al. (2024) . A Multicenter Prospective Randomized Controlled Trial Comparing Cxbladder Triage to Cystoscopy in Patients With Microhematuria.

The Safe Testing of Risk for Asymptomatic Microhematuria Trial. The Journal of Urology Vol 212 1-8 Jul 2024.

EXTENDING THE MOAT AROUND OUR BUSINESS

8

ALTERNATIVE REVENUE STREAMS
The AUA guideline also provides Pacific Edge with

several options to build momentum despite the

non-coverage determination on L39365. We expect

to continue to receive reimbursement from

contracted US payers without interruption, notably

Kaiser Permanente, the US Veterans Administration,

Blue Cross Blue Shield plans under a group

purchasing agreement, and from non-contracted

commercial payers.

Similarly, we expect to improve collections from

non-contracted commercial payers through three

initiatives.

The first is to appeal denied claims to “external

review” where permitted, using the AUA

microhematuria guideline as evidence to reverse

the initial claim denial. The second is to establish

‘client billing’ relationships with hospitals and large

urology group practices that are committed to

Cxbladder Triage and agree to pay Pacific Edge

for the test and separately to seek reimbursement

from the commercial payers. This model provides

financial benefits to Pacific Edge and the client. The

third is already in process, and that is to have our

clinical evidence reviewed by ‘data curators’. These

third parties make their reviews available through a

subscription to commercial payers, with commercial

payers granting positive medical policy to tests with

favorable reviews.

Pacific Edge already has a favorable rating from

ECRI

2

a rating as high as any molecular diagnostic

biomarker for oncology in their database, and is

seeking further favorable reviews. For commercial

claims that ultimately result in a denial, we intend

to continue our enhanced patient responsibility and

patient assistance program to drive some payment

from patients for our test.

In New Zealand — our largest market outside of the

US — we are seeking to further entrench Cxbladder

with a national pathway for hematuria evaluation.

The moves to extend our global reach and diversify

our revenue with distribution agreements in Israel,

Latin America and Southeast Asia continue to offer

promise, delivering still small but steadily growing

test volumes from these markets.

2

ECRI is the Emergency Care Research Institute (https://home.ecri.org/)

“The AUA guideline...

provides Pacific

Edge with a number

of options to build

momentum.”

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

9

These efforts will be supported by our investment
in the digitalization initiatives that will further

drive the adoption of our tests and improve

the experience for clinicians and patients. We

are seeing evidence that these initiatives are

embedding Cxbladder in clinical practice, with

tests ordered and resulted through our digital

integrations being less impacted by the adverse

LCD.

RESEARCH AND DEVELOPMENT

We are targeting the development of a kit-

based in-vitro diagnostic test (IVD) to accelerate

momentum in new markets globally. Key steps

to achieve this goal include understanding the

global regulatory requirements and prototyping

a test that is aligned with them. We are aiming to

manufacture a test that meets these goals and

commencing analytical and clinical validation

during FY27. The R&D, Digital and Operations

teams all have a shared focus on readying our

lab operations for the commercial scaling of

Triage Plus.

OUTLOOK

Pacific Edge is well positioned to leverage the AUA

guideline inclusion to entrench our first-mover

advantage and accelerate growth in the year

ahead. We expect to achieve this goal increasing

clinical throughput, expanding sales team

productivity, and strengthening our evidence base

to support reimbursement and coverage decisions

for both Triage Plus and Monitor Plus.

The key growth catalyst will be the successful

reconsideration of the LCD. However, we are also

confident we can deliver significant incremental

improvements to broaden access through

electronic ordering and commercial insurance

uptake and enhancing reimbursement through

our client billing program. Meanwhile, in the longer

term the advancement of IVD kit development to

support international expansion will catalyze more

rapid adoption globally.

While the challenges of Medicare coverage over

the last year have been disappointing, I remain

confident we have laid the groundwork for scalable

growth and increased shareholder value.

I look forward to sharing more with you at our

Annual Shareholder’s Meeting in early August.

With my warm regards,

Dr Peter Meintjes

Chief Executive

CHIEF EXECUTIVE'S REPORT

10

- The total addressable market for Cxbladder in the US is estimated to be more than US$4.4b
1

and

US$8.5b globally.

- Pacific Edge has laboratory infrastructure in place in New Zealand and the US with a lab

scalability plan to handle more than 300k tests per annum. This can be scaled further with

additional laboratory footprint as and when needed.

- The company enjoys a first mover advantage with a “moat” from compelling clinical evidence

and its inclusion in the AUA microhematuria guidelines.

PACIFIC EDGE’S GLOBAL FOOTPRINT

PACIFIC EDGE’S GLOBAL OPPPORTUNITY

1

Pacific Edge estimates. For the assumptions underlying these estimates please see slide 33

of the FY 25 results presentation released to the NZX on 30 May 2025.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

11

STRATEGY
Cxbladder delivers actionable information that can advance the standard of care that

physicians offer to patients, improving the patient experience, quality of life, and healthcare

outcomes, while reducing the total cost of care and improving healthcare equity

1

.

OUR PEOPLE

EXCELLENT PATIENT EXPERIENCE

AND ACCURATE RESULTS

OUR PROCESSES

EARLY DETECTION AND

CLINICALLY ACTIONABLE CARE

OUR IP, KNOWLEDGE

AND EXPERIENCE

INNOVATION PIPELINE FOR

CLINICAL APPLICATIONS

OUR CLINICAL STUDIES

PARTNER SITES

INCLUSIVE WORKPLACE

DRIVEN BY OUTCOMES

OUR INVESTORS

INCREASED LONG-TERM


SHAREHOLDER VALUE

EVIDENCE,

COVERAGE AND

GUIDELINES

INPUTSOUTPUTS

A VALUES-DRIVEN, DIVERSE, RESULTS-FOCUSED CULTURE

SCALABLE PROCESSES, TRAINING & QUALITY SYSTEMS, CONTINUOUS IMPROVEMENT

DIGITALIZED ARCHITECTURE, AUTOMATED OPERATIONS, REAL-TIME ANALYSIS

1

Budgetary Impact of Including the Urinary Genomic Marker Cxbladder Detect in the Evaluation of Microhematuria Patients -PubMed (nih.gov);

Davidson, Peter; Presentation to Urofair, 2022, time to first specialist assessment.

ADOPTION,

RETENTION AND

REVENUE

GENERATION

RESEARCH AND

INNOVATION

IMPROVING SOCIAL OUTCOMES AND CREATING

SHAREHOLDER VALUE

Pacific Edge is focused on improving people’s lives and patient outcomes by providing

leading solutions for the early detection and management of bladder cancer. We are

delivering on this goal and driving long-term shareholder value by building on our strong

foundations and focusing on three strategic pillars.

VALUE CREATION THROUGH THREE PILLARS

12

STRATEGY
2

ASP: US Operating Revenue in USD / US Commercial Test Volumes

3

LUGPA: Large Urology Group Practice Association; AACU: American Association of Clinical Urologists

ADOPTION,

RETENTION AND

REVENUE

GENERATION

RESEARCH AND

INNOVATION

ADOPTION, RETENTION AND REVENUE GENERATION

The short-term driver of our performance is to generate revenue by accelerating the

adoption of Cxbladder as the standard of care with clinicians’ healthcare providers, and

funders and retaining those customers and clinicians who understand its value.

FY 25 Achievements

• Global Commercial test volumes of 24,642 for FY 25 down 9.9% on FY 24 with falling

US volumes offset by an 18.5% uplift in APAC

• US test sales/FTE rise to 405.6 in Q4 25, +6.4% on Q4 24 and +69.5% on Q4 23

• US ASP

2

increases to US$594 in FY 25 vs US$584 in FY 24

• Tests for Medicare and Medicare Advantage represented 53% of US commercial tests

in FY 25 vs 58% in 1H 24 demonstrating our success in growing contracted payer

revenue

• Triage Plus achieves a draft Medicare price of US$1,018.44, an increase of 34% when

contrasted with the current pricing of US$760 per test

EVIDENCE COVERAGE AND GUIDELINES

The medium-term driver of our performance is to enhance our clinical evidence portfolio

and engage with the clinical community on the value of our tests within the frameworks

of Analytical Validity, Clinical Validity, and Clinical Utility, the end points required for

coverage decisions and guideline inclusion.

FY 25 Achievements

• Cxbladder Triage was included in the American Urological Association

microhematuria guideline with a ‘Grade A’ evidence rating, the only biomarker to

achieve this status

• We built a consensus among AUA, LUGPA

3

and AACU advocating for a revision

to ‘Genetic Testing for Oncology: Specific Tests (L39365)’ Local Coverage

Determination

• We published new analytical validation data for Triage, Detect and Monitor, while

analytical validation and clinical validation publications for Triage Plus were

submitted for peer review

• Further clinical utility evidence for Triage was published as an abstract by Kaiser

Permanente and presented at the 2025 AUA annual meeting. The study is in

peer review and we are anticipating publication in FY26 Q3

RESEARCH AND DEVELOPMENT

To drive long-term growth, we invest in technology and product innovation to maintain

our leadership position in bladder cancer diagnostics.

FY 25 Achievements

• We are readying our R&D, Digital and Lab Operations for the commercial scaling

of Triage Plus and the development of Monitor Plus

• We commenced development of a kitted IVD (in vitro diagnostic) product from

our existing lab service called Triage Plus IVD, for decentralized lab deployment

and international market expansion

• We continued to engage with industry and academic research and development

collaborations to address unmet clinical needs in bladder cancer diagnosis and

management

EVIDENCE,

COVERAGE AND

GUIDELINES

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

13

ADOPTION, RETENTION AND REVENUE GENERATION
A LEANER AND MORE PRODUCTIVE ORGANIZATION

Pacific Edge has made meaningful progress toward becoming a leaner and more productive

organization, with a sustained focus on financial discipline and operational efficiency.

The average number of full-time sales employees was reduced from 32.7 in Q4 23 to 16.0 in Q4 25 as part

of a broader effort to conserve cash while maintaining service coverage. Despite the smaller team, sales

force efficiency improved significantly, with the quarterly number of tests per full-time sales employee rising

69% from 239 to 406 over the same period. This outcome reflects a deliberate focus on the most profitable

territories and accounts, alongside greater alignment with clinicians who understand and value the clinical

utility of Cxbladder.

The average number of ordering

clinicians remained steady on

Q4 24 levels, and tests per

US ordering clinician were

stable despite the Medicare

uncertainty. We expect these

efficiencies to be sustained and

with re-coverage we expect

them to be a key driver of

growth and shareholder value.

The average sales price (ASP)

1


rose from US$584 in FY 24

to US$594 in FY 25 despite a

decline in the ASP in the second

half of FY 25 due to accrual

timing and revenue provisions.

This increase was supported by

improved patient contribution

frameworks, improved

engagement with Kaiser

Permanente following the

integration of our systems

with Kaiser’s electronic

medical records system (EMR)

and strengthened billing

documentation for Medicare

Advantage. Cash collections

also improved and are expected

to remain strong. We expect the

average sales price to decline

in the wake of the cessation of

Medicare coverage, but to return

to growth once we regain it.

1

ASP: US Operating Revenue in USD / US Commercial Test Volumes

US SALES FORCE EFFICIENCY

US CLINICAL COMMITMENT

US COMMERCIAL TEST VOLUMES AND ASP

1


27.3

29.7

33.0

32.7

30.0

27.7

20.7

16.0

14.7

15.0

15.3

16.0

222.2

225.8

200.9

239.3

287.6

265.1

292.3

381.2

402.6

378.8378.8

405.6

-

10

60

110

160

210

260

310

360

410

-

10

20

30

40

50

60

70

80

895

978

1,082

1,150

1,232

1,147

1,016

915

867

890

866

914

6.8

6.8

6.1

6.8

7.0

6.4

5.9

6.7

6.8

6.4

6.7

7.1

-

1.0

2.0

3.0

4.0

5.0

6.0

7.0

8.0

-

200

400

600

800

1,000

1,200

1,400

1,600

1,800

Q1 23Q2 23Q3 23Q4 23Q1 24Q2 24Q3 24Q4 24Q1 25Q2 25Q3 25Q4 25

TESTS/ORDERING CLINICIAN (RHS)

$-

$100

$200

$300

$400

$500

$600

$700

-

2,000

4,000

6,000

8,000

10,000

12,000

14,000

16,000

TEST VOLUME

AVERAGE US SALES PRICE (US$)

US AVERAGE SALES PRICE (RHS)

1H 22

$472

$470

$493

$519

$562

$571

$613

$618

7,476

2H 22

8,276

1H 23

10,622

2H 23

12,450

1H 24

13,550

2H 24

9,956

9,913

10,177

Q1 23Q2 23Q3 23Q4 23Q1 24Q2 24Q3 24Q4 24Q1 25Q2 25Q3 25Q4 25

US TEST VOLUME/SALES FTE (RHS)

US ORDERING CLINICIANS

TEST/ORDERING CLINICIAN

AVERAGE SALES FTE

TEST VOLUME/SALES FTE

1H 252H 25

9,913

10,177

14

!"
ADOPTION, RETENTION AND REVENUE GENERATION

PREPARING FOR THE LAUNCH OF TRIAGE PLUS

Pacific Edge is preparing for the commercial launch of Cxbladder Triage Plus, a next-

generation, multi-modal (RNA and DNA) diagnostic test for the evaluation of hematuria.

Triage Plus offers superior clinical performance to the existing Triage test offering increased utility to

clinicians managing patients with hematuria. Once launched it will be our sole test for hematuria evaluation

in the US.

A full-scale launch of Triage Plus is contingent on Medicare coverage. The Centers for Medicare & Medicaid

Services (CMS) has proposed a price of US$1,018 per test, significantly above the US$760 pricing of our

existing tests. This lift, once reliable Medicare coverage is obtained, is expected to materially improve

margins and lower the number of tests per Account Executive required to reach profitability, enabling faster

and more efficient scaling. It will also extend the US addressable market by nearly US$1 billion to as much as

US$4.4 billion.

1


Analytical validation and clinical validation studies for Triage Plus have been submitted for peer-reviewed

publication, expected imminently. Upon publication, Pacific Edge will submit a reconsideration request to

our Medicare Administrative Contractor, Novitas. Triage’s inclusion in the American Urological Association’s

(AUA) microhematuria guideline provides medical policy support, increasing the likelihood of coverage for

Triage Plus. Additional data under peer review from Kaiser Permanente further validating the clinical and

economic value of Triage Plus is also expected to support coverage of the test.

To support the launch, Pacific Edge will invest in expanding digital capabilities and capacity at the PEDUSA

laboratory. It is also streamlining workflows for improved operational efficiency. The sales team structure will

be optimized to support broader product adoption, with refreshed sales and marketing materials aligned

with AUA Guideline messaging. Medical education will also be strengthened through podium presentations,

a speaker bureau, and continued evidence development.

1

Pacific Edge estimates. For the assumptions underlying these estimates please see slide 33 of the FY 25 results presentation

released to the NZX on 30 May 2025

2

NMIBC is non-muscle invasive bladder cancer

3

RDM: Residual Disease Monitoring

4

TRM: Therapeutic Response Monitoring

CXBLADDER RNA TESTS IN MARKETCXBLADDER RNA+DNA TESTS COMING

TO MARKET

!"

PATIENT/DISEASE MANAGEMENT

(CLINICAL DECISION MAKING)

SURVEILLANCE

(RDM

3

, TRM

4

, RECURRENCE)

PATIENT/DISEASE MANAGEMENT

(CLINICAL DECISION MAKING)

SURVEILLANCE

(RDM

3

, TRM

4

, RECURRENCE)

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

15

EVIDENCE COVERAGE AND GUIDELINES
CXBLADDER INCLUDED IN THE AUA GUIDELINE —

A COMPANY DEFINING MILESTONE

The American Urological Association’s inclusion of Cxbladder Triage as a recommended

alternative to the standard of care in the evaluation of microhematuria patients, represents a

substantial strategic milestone on which to build our commercial operations.

The guideline, released in late February, will help to reduce the burden of unnecessary cystoscopies for

lower risk patients, resulting in less patient discomfort, lower morbidity, and improved access to care for

those who need it by reducing wait times.

It will also play a central role in our reconsideration requests to Novitas to regain Medicare coverage of

Cxbladder Triage (see page 17).

The guideline states urologists may use urine-based biomarkers for intermediate-risk patients presenting

with microhematuria to assist their decision on whether to defer a cystoscopy: “In appropriately counseled

intermediate-risk patients who want to avoid cystoscopy and accept the risk of forgoing direct visual

inspection of the bladder urothelium, clinicians may offer urine cytology or validated urine-based tumor

markers... to facilitate the decision regarding the utility of cystoscopy. Renal and bladder ultrasound should

still be performed in these cases.”

Intermediate risk patients represent a large serviceable market for Triage, amounting to anywhere from 40-

70% of all microhematuria patients, or up to 3.5 million patients per year in the US alone.

1

This figure represents the base-line population indicated by the guideline, but we expect through the

development of further evidence and clinician education to extend our addressable market to almost all

patients presenting with hematuria that do not have a benign cause identified.

In a significant achievement, the guideline mentions Cxbladder Triage as the only urine-based biomarker

test that has ‘Grade A’ evidence from a randomized controlled trial (the STRATA study ) in support of this

recommendation.

The study was the first randomized controlled trial of any urine biomarker and demonstrated that Cxbladder

Triage could safely and effectively reduce cystoscopies by as much as 59% without missing tumors. The

specific mention of Cxbladder Triage in the guideline reinforces our first mover advantage and establishes a

high evidentiary standard that any other test must meet to be competitive.

1

Pacific Edge estimates. For the assumptions underlying these estimates please see slide 33 of the FY 25 results presentation

released to the NZX on 30 May 2025.


Copyright © 2025 American Urological Association Education and Research, Inc. ®

1

Any person or company accessing this guideline with the intent of using the guideline for promotional purposes must obtain a licensable copy.


MMIICCRROOHHE EMMAATTUURRIIAA::

AAUUAA//SSUUFFUU GGUUIIDDEELLIINNEE ((22002200,, AAMMEENNDDEEDD 22002255))

Guideline Panel

Daniel A. Barocas, MD, MPH;* Stephen Boorjian, MD;* Ronald Alvarez, MD, MBA;

Tracy M. Downs, MD; Cary P. Gross, MD; Blake Hamilton, MD; Kathleen Kobashi, MD;

Robert Lipman; Yair Lotan, MD; Casey Ng, MD; Matthew Nielsen, MD, MS; Andrew

Peterson, MD; Jay Raman, MD; Rebecca Smith-Bindman, MD

* Equal author contribution

Amendment Panel

Daniel A. Barocas, MD, MPH, FACS; Yair Lotan, MD; Richard S. Matulewicz, MD, MSCI,

MS; Jay D. Raman, MD, FACS, FRCS(Glasg); Mary E. Westerman, MD

Amendment Staff and Consultants

Lauren J. Pak, MHS, MS; Erin Kirkby, MS; Lesley Souter, PhD

SUMMARY

Purpose

The purpose of this guideline is to provide a clinical framework for the diagnosis, evaluation, and follow-up of microhematuria

(MH).

Methodology

OVID was used to systematically search MEDLINE and EMBASE databases for articles evaluating hematuria using criteria

determined by the expert panel. The initial draft evidence report included evidence published from January 2010 through

February 2019. A second search conducted to update the report included studies published up to December 2019. Five

systematic reviews and 91 primary literature studies met the study selection criteria and were chosen to form the evidence

base. These publications were used to create the majority of the clinical framework. When sufficient evidence existed, the

body of evidence for a particular modality was assigned a strength rating of A (high), B (moderate), or C (low); and evidence-

based statements of Strong, Moderate, or Conditional Recommendation were developed. Additional information is provided

as Clinical Principles and Expert Opinions when insufficient evidence exists. In 2024, this Guideline was reviewed via the

AUA update literature review (ULR) process, which identified 82 studies for full-text review that were published between

December 2019 and June 7, 2024. Of those 82 studies, 23 met inclusion criteria for qualitative synthesis. The subsequent

amendment is based on data released since the initial 2020 publication of this Guideline.



American Urological Association (AUA)/

Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction (SUFU)

APPROVED BY THE AUA

BOARD OF DIRECTORS

FEBRUARY 2025

Authors’ disclosure of potential

conflicts of interest and

author/staff contributions appear

at the end of the article.


© 2025 by the American

Urological Association


16

EVIDENCE COVERAGE AND GUIDELINES
A CLEAR PATH TO REGAINING MEDICARE COVERAGE

Pacific Edge's primary disappointment for the year was the loss of Medicare coverage after

Novitas, the Medicare Administrative Contractor with responsibility for our U.S. laboratory,

finalized the ‘Genetic Testing for Oncology: Specific Tests (L39365)’ Local Coverage

Determination (LCD).

Medicare coverage of our tests ceased in late April 2025 when the LCD became effective, despite vigorous

political advocacy and the exploration of legal avenues.

This decision reversed five years of coverage, during which Cxbladder tests were reimbursed in over 98%

of claims submitted, at US$760 per test. Medicare tests accounted for the majority of US volumes and

contributed approximately 56% of FY 25 operating revenue. The process that led to non-coverage failed to

review the most current and relevant clinical evidence, including the STRATA

1

study and the new American

Urological Association (AUA) microhematuria guidelines. It removed access to guideline-recommended

testing, a poor outcome for Medicare patients and the urology community.

Pacific Edge is pursuing two concurrent strategies to restore coverage. The first is submitting formal

reconsideration requests to Novitas, supported by new clinical evidence. A request for Cxbladder Triage

was submitted in March 2025, backed by STRATA and the AUA guideline. A second for Cxbladder Monitor

followed in May, supported by two new Australian real-world evidence studies. A request for Triage Plus will

follow the publication of analytical and clinical validation studies, expected later in 2025 as detailed on

page 21.

Industry experts typically estimate it is likely to take 6-9 months for Novitas to consider a valid submission

of a single product with only a small number of new supporting publications to be reviewed.

Beyond these immediate reconsideration requests the company’s clinical evidence generation program

is developing a raft of new evidence to support further reconsideration requests or — in the event of the

company being successful with the proximate opportunities — entrench coverage and build the moat

around the business.

The second strategy is to appeal claim denials through the Medicare Appeals Process (see following page).

1

Lotan Y, et al (2024) A Multicenter Prospective Randomized Controlled Trial Comparing Cxbladder Triage to Cystoscopy

in Patients With Microhematuria. The Safe Testing of Risk for Asymptomatic Microhematuria Trial. J Urol 2024.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

17

REIMBURSEMENT THROUGH APPEAL
Pacific Edge can pursue reimbursement for its Cxbladder tests through the Medicare

Appeals Process, which comprises five sequential levels.

The process, which takes several months, begins

with a redetermination by Novitas, Pacific Edge’s

Medicare Administrative Contractor. Pacific Edge will

make its appeal supported by the updated American

Urological Association (AUA) microhematuria

guideline and the STRATA study. The AUA guideline

in particular supports the argument that the tests are

"medically reasonable and necessary," a key criterion

under the U.S. Social Security Act for Medicare

coverage.

If the redetermination is unfavorable, Pacific Edge

will then request a reconsideration by a Qualified

Independent Contractor (QIC). Should the QIC

also deny the claim, Pacific Edge may escalate the

appeal through the US Department of Health and

Human Services to the Office of Medicare Hearings

and Appeals (OMHA) for a hearing before an

Administrative Law Judge (ALJ). Further appeals

can be made to the Medicare Appeals Council and,

subsequently, to a Federal District Court if necessary.

The company is committed to pursuing these appeals

to the fullest extent.

MEDICARE APPEALS PROCESS

Redetermination by the Medicare

Administrative Contractor

Reconsideration by a

Qualified Independent Contractor

Hearing before an

Administrative Law Judge

Review by the Medicare

Appeals Council

Judicial Review in

Federal District Court

EVIDENCE COVERAGE AND GUIDELINES

18

RESEARCH AND INNOVATION
PURSUING A KITTED IVD IN INTERNATIONAL MARKETS

Pacific Edge is advancing a kitted in-vitro diagnostic (IVD) version of its Cxbladder

technology to capture international market opportunities outside the U.S.

These international markets represent an estimated addressable opportunity of US$4.1 billion

1

— nearly as

large as the U.S. market. Given the diversity in market access requirements, a decentralized approach that

allows accredited labs to run an IVD-approved version of the test and obtain reimbursement is the preferred

way to go to market.

Unlike the current laboratory-based service model, an IVD is typically sold as a physical kit, enabling

distribution to third-party laboratories with the appropriate accreditation and equipment to run the test

themselves, thus expanding access in countries where a central testing service is not practical nor economic.

This strategy broadens Pacific Edge’s global reach while further strengthening the competitive “moat”

around the Cxbladder platform.

Pacific Edge has begun prototyping the Triage Plus IVD product and is accelerating development efforts

with support from its current capital raise. The goal is to produce working prototypes by the end of calendar

year 2025, followed by manufacturing and validation activity in 2026.

To support international deployment, Pacific Edge is laying the foundation for regulatory approvals under

IVDR (Europe), FDA (U.S.), and ISO-13485 (Rest of World). Achieving IVD regulatory status will not only

expand market access and establish government reimbursement in targeted countries, but also raise the

bar for clinical validation, making it more difficult for competitors to match Cxbladder’s evidence base and

clinical credibility.

1

Pacific Edge estimate. This estimate includes the New Zealand market where the company is operating a laboratory-based service. For further detail on

the assumptions supporting underlying this estimate please see slide 33 of the FY 25 results presentation released to the NZX on 30 May 2025.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

19

IMPROVING THE CXBLADDER CUSTOMER EXPERIENCE
Pacific Edge’s investments in digitalization are delivering value by embedding Cxbladder

more deeply into clinical workflows and reducing friction in test ordering and results

delivery. These enhancements are improving the end-to-end experience for physicians and

patients, making it easier to adopt and use Cxbladder in everyday practice.

We offer a range of digital connection options to suit different provider needs, including direct electronic

medical record (EMR) integrations like our one-to-one interface with Kaiser Permanente and one-to-many

integrations with partners such as Lumea Digital Pathology in the US and Awanui in New Zealand. We have

also launched a Clinician Customer Portal for all other users, streamlining test ordering and tracking and

replacing paper or email ordering.

These digital tools simplify both in-clinic and in-home sampling workflows, optimize test kit handling, and

provide real-time order visibility and result access. For Pacific Edge, the benefits include faster processing,

fewer errors, and reduced demands on customer service and sales teams — contributing to a more efficient

and scalable operation.

RESEARCH AND INNOVATION

The Cxbladder Clinician Portal streamlines test ordering and results delivery

20

CLINICAL EVIDENCE PROGRAM
THE FOUNDATIONS OF OUR LONG-TERM VALUE CREATION

Our clinical study program is at the foundation of Pacific Edge’s value. We are proud to

generate the compelling clinical evidence required to change physician behavior; evidence

that is founded on the frameworks of Analytical Validity, Clinical Validity, and Clinical Utility,

with the end points and sample sizes required for coverage decisions and guideline inclusion.

STUDYGOALPOPULATION AND

USE

STATUS

STRATA

Safe Testing of Risk

for AsymptomaTic

MicrohematuriA

• CU Triage

• CV/CU Triage Plus

(retrospective)

• Microhematuria

(MH)

• Risk stratification

• Recruitment closed with 555 patients

including 223 low risk patients (test and

control)

• Interim analysis results published leading to

AUA Guidelines inclusion in 2025 update

• Database lock expected June 2025 and

Clinical Study Report (CSR) expected

October 2025

DRIVE

Detection and Risk

stratification In VEterans

presenting with

hematuria

• CV Triage Plus for

a Veterans’ cohort

• Data for MH

pooled analysis

• MH and gross

hematuria (GH)

• Risk stratification

• Enrolment closed with 710 patients including

48 tumour confirmed patients from 10 US

VA sites

• Database lock completed and publication

submitted April 2025

microDRIVE

Detection and Risk

stratification In VEterans

presenting with

hematuria

• CV Triage Plus

• Data for MH

pooled analysis

• MH

• Risk stratification

• Currently 330 samples received to date with

8 urothelial carcinoma (UC) cases confirmed

• Study expanded to 4 active sites with 1-2

more sites at feasibility assessment

• The target is 1000 patients with 35 tumour

confirmed patients with last patient in

projected to be delayed beyond Q4 2025

and more likely Q3-4 2026

AUSSIE

Australian Urologic risk

Stratification of patientS

wIth hEmaturia

• CV Triage Plus

(Australian cohort)

• Data for MH

pooled analysis

• MH and GH

• Risk stratification

• The target is 35 UC confirmed patients

including a minimum of 10 microhematuria

(MH) UC confirmed

• Currently 662 subjects enrolled with 41 UC

confirmed (gross hematuria (GH) + MH)

including 6 MH UC patients

• Last patient projected to be in Q3 2025

POOLED ANALYSIS• CV Triage Plus• MH and GH

• Risk stratification

• MH (and separately GH) patient data from

DRIVE, AUSSIE & microDRIVE will be pooled

and analysed

• GH paper submission is expected in 2026

and MH pooled analysis is delayed due to

microDRIVE

LOBSTER

LOngitudinal Bladder

cancer Study for

Tumor Recurrence

• CV of Monitor and

Monitor


Plus

• Surveillance

• Risk stratification

• Enrolment will be complete when 75 UC

recurrences are observed

• Currently 409 subjects enrolled with 1005

samples & 65 confirmed UC recurrences

• Last patient projected to be in Q4 2025

CREDIBLE

Cystoscopic REDuction

In BLadder Evaluations

for microhematuria

• CU Triage Plus


• MH

• Risk stratification

• Contracts completed (15/15), study level

Institutional Review Board (IRB) approvals &

site level IRB approvals (14/15)

• Site authorized to enroll (9/15), 5 more

expected end June & first subject was

enrolled 29 April

• 10 subjects currently enrolled

Dates are calendar year not financial years

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

21

SUSTAINABILITY
22

SUSTAINABILITY, GOVERNANCE AND OVERSIGHT
Accountability for the implementation of Pacific Edge’s sustainability goals sits with the CEO. Oversight

of the execution of our sustainability strategy, including the ESG program and compliance reporting, is

delegated to the Sustainability Committee (SC).

The SC is chaired by the Chief Financial Officer (CFO) and comprises senior leaders and key functional

representatives from New Zealand and the USA. It meets at least quarterly to monitor progress and

performance, and reports through to the Audit and Risk Committee (ARC). It also meets regularly with the

ARC to ensure strong board oversight of progress.

SUSTAINABILITY

PACIFIC EDGE IS FOUNDED ON IMPROVING SOCIAL OUTCOMES

Pacific Edge is focused on improving people’s lives and patient outcomes by providing

leading solutions for the early detection and management of bladder cancer.

We are delivering on our purpose, and driving long-term shareholder value, by building strong foundations

and focusing on three strategic areas as we set out on pages 12-13 of this report.

We are working hard to embed sustainability considerations into our strategic priorities and decision-

making. The table below shows the areas we have identified as important to driving better outcomes for all

our stakeholders.

WHERE WE ARE FOCUSING OUR EFFORTS

OUR SOCIAL IMPACTOUR ENVIRONMENTAL IMPACTOUR GOVERNANCE PRACTICES

Improving healthcare access,

quality of care and patient

outcomes

• Extending the adoption of

our tests by leveraging our

inclusion in the American

Urological Association (AUA)

microhematuria guidelines

Product environmental

stewardship

• Sustainable sourcing

• Using resources efficiently and

responsibly

Risk management

• Strong risk, governance and

management practices

• Data security

• Operational resilience

An inclusive, engaged and safe

workforce

• Employee engagement

• Career pathways and

development

• Gender equality

• Safety and wellbeing

Emissions reduction

• Energy efficiency

• Business travel intensity

• Reduced laboratory emissions

from running Cxbladder tests

• Improved logistics efficiency

Operational quality and

compliance

• Product safety

• Quality manufacturing

• Efficiency and effectiveness

Responsible supply chain

• Working with suppliers to

ensure they have ethical codes

of conduct (including the

prevention of modern slavery)

Climate-related disclosures

• NZ Climate Standards

compliance

Engaging our stakeholders

• Meeting our commitments as an

employer

• Meeting our customer needs

• Creating shareholder value

Supporting our communities

• Support for local initiatives and

events

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

23

24

SUSTAINABILITY
FY 25 PROGRESS AND HIGHLIGHTS

We are pleased to report solid progress towards our sustainability goals over

the past year, with our key achievements highlighted below.

OUR SOCIAL IMPACTOUR ENVIRONMENTAL IMPACTOUR GOVERNANCE PRACTICES

Improving healthcare access,

quality of care and patient

outcomes

• Delivered 24,642 commercial

tests to over 15 countries

Product environmental

stewardship

• Key projects underway, aimed at

reducing supply chain footprint

and reducing use of chemicals

and single-use plastics

Risk management

• FMEA

1

risk management

framework embedded across the

business with routine reporting

• Development of a Tax

Governance Policy that provides

a framework to facilitate the

efficient management of Pacific

Edge’s tax obligations in line

with our low-risk appetite

• Updated our assessment and

reporting of climate related risks

An inclusive, engaged and safe

workforce

• Strong engagement from our

people. In FY 24

2

our staff survey

showed:

-

79.6% of Pacific Edge people

reported satisfaction in their

roles

-

>80% of Pacific Edge people

reported a clear understanding

of the company’s vision and

purpose

• No lost time to injuries

Emissions reduction

• Second greenhouse gas

emission inventory completed

showing a 5.9% reduction

in carbon intensity per test

compared to prior year — Target

of 20% reduction by 31 March

2029

• PwC New Zealand assured

Scope 1 and Scope 2 emission

disclosures

Operational quality and

compliance

• Further evolved our operational,

quality and compliance

framework

• Pacific Edge has successfully

managed all external compliance

audits in all areas of the business

Responsible supply chain

• Full supplier diagnostic

completed

• Working with major suppliers to

ensure they include conditions

around modern slavery and

human rights

Climate-related disclosures

• NZ Climate Standards reporting,

including voluntary Scope 3

inclusion

Supporting our communities

• Sponsored bladder cancer

patient advocacy organisations

to empower patients and build

awareness of the disease

1

FMEA: Failure Mode and Effects Analysis

2

Due to a change in the timing of the annual engagement survey, the next update of employee engagement metrics will be provided in

the FY 26 annual report

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

25

OUR SOCIAL IMPACT
IMPROVING HEALTHCARE ACCESS, QUALITY OF CARE, AND PATIENT OUTCOMES

Cxbladder delivers actionable information that can advance the standard of care that

physicians offer, enhancing the patient’s experience and quality of life to support improved

healthcare outcomes, while helping to reduce the total cost of care. Our in-home sampling

kits improve healthcare equity by bringing the benefits of Cxbladder to poorer and rural

communities that face barriers to accessing specialist care.

Ultimately our success in achieving these goals is best measured by the adoption of our tests. Over the last

year commercial volumes fell by 9.9% to 24,642 tests, well below the potential we see for the tests, with the

fall principally reflecting the reduced reach of our smaller sales force as we moved to preserve capital amid

uncertainty over continued Medicare coverage of our tests.

Unfortunately, we expect this trend to continue into the new financial year after Novitas, the Medicare

Administrative Contractor with responsibility for our US laboratory, finalized the ‘Genetic Testing for

Oncology: Specific Tests (L39365)’ Local Coverage Determination based on out-of-date evidence

and despite the inclusion of Cxbladder Triage in the American Urological Association’s (AUA) new

microhematuria guideline. The decision was a poor outcome that has increased the patient burden of

unnecessary invasive examinations, including the costs to healthcare payers. However, against this — as we

have detailed elsewhere in the report — we believe the new guideline and our ongoing evidence generation

program support our efforts to regain coverage.

We have a wealth of evidence demonstrating the role Cxbladder plays in delivering these improved social

outcomes. We were included in the guideline based on our groundbreaking STRATA study

1

, which was

published in the Journal of Urology in May 2024 and headlined at the AUA annual meeting last year. The

study demonstrated the Clinical Utility of Cxbladder Triage in safely reducing the number of invasive

cystoscopies. Specifically, it showed clinicians performed 59% fewer cystoscopies when they could use the

information generated from the test.

This year a large real-world study undertaken by Kaiser Permanente

2

has reinforced the STRATA study.

Preliminary data of the study presented at the 2025 AUA meeting demonstrated the Clinical Utility of

Cxbladder Triage, in safely reducing patients presenting with hematuria from unnecessary cystoscopies.

The authors of that study concluded: “...Cxbladder Triage testing resulted in significantly decreased

cystoscopy and imaging utilization in those classified as low risk without any negative patient outcomes,

while simultaneously demonstrating increases in the cystoscopy and bladder cancer detection rate in the

physician directed protocol group.”

The economic and social benefits of our tests are well established by studies in New Zealand and Pacific

Edge’s Modelling, the latter showing that Cxbladder used in hematuria evaluation could save US healthcare

providers approximately US$500 per patient by avoiding unnecessary procedures

3

.

Further detail on our clinical evidence can be found on our website and on page 21 of this report.

1

Lotan et al. (2024). A Multicenter Prospective Randomized Controlled Trial Comparing Cxbladder Triage to Cystoscopy in Patients With Microhematuria.

The Safe Testing of Risk for Asymptomatic Microhematuria Trial. The Journal of Urology Vol 212 1-8 Jul 2024.

2

Loo R.K., et al (2025) Clinical Utility of a Urine Biomarker (Cxbladder Triage) Compared to a Standard of Care for Microscopic Hematuria Evaluations in a

Large Independent Delivery Network. Abstract submitted to the AUA 2025 meeting.

3

Tyson et al. (2023). Budgetary Impact of Including the Urinary Genomic Marker Cxbladder Detect in the Evaluation of Microhematuria Patients. Urology

practice, 11(1), 54–60. https://doi.org/10.1097/UPJ.0000000000000489

SUSTAINABILITY

26

1
Tyson et al (2024) Budgetary Impact of Including the Urinary Genomic Marker Cxbladder Detect in the Evaluation of Microhematuria Patients -

PubMed (PMID: 37914255)

CXBLADDER DELIVERS CLINICAL UTILITY, PATIENT

SATISFACTION AND ECONOMIC VALUE

Cxbladder offers improvement over the standard of care,

avoids unnecessary procedures and streamlines workflow

when used to intensify or de-intensify hematuria evaluation

or in the surveillance for the recurrence of bladder cancer. For

healthcare payers, Cxbladder offers substantial total cost savings

per patient

1

.

CANCER INCIDENCE IN MICROHEMATURIA PATIENTS

Incidence of bladder cancer in microhematuria populations is 5%

CYSTOSCOPIES SAFELY AVOIDED USING CXBLADDER

With Cxbladder, 78% of patients can avoid cystoscopy,

22% receive cystoscopy, 5 cancers found

Microhematuria patient

with no cancer

Cytoscopy avoided

Microhematuria patient

with cancer

Normal Cytoscopy

Cytoscopy undertaken

and cancer found

Cxbladder can

spare up to 1.5

million patients in

the US per year

from cystoscopy

SUSTAINABILITY

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

27

AN INCLUSIVE, ENGAGED WORKFORCE
The oncology diagnostics marketplace is highly competitive, and our

continued success depends on attracting, retaining and developing high

caliber talent. A strong attraction and recruitment strategy is essential to

securing the expertise needed to support ongoing growth.

We are committed to hiring high-quality, experienced leaders and providing all

employees with development opportunities that support personal growth and

business success. This includes capability-building initiatives designed to help our

people to do great work and progress in their careers.

We actively encourage diversity and recognize the benefits it brings to our business.

We appreciate the wide range of backgrounds and experiences of our people and

value the choices they have made to be part of our team.

Our approach to recruitment, performance and reward is overseen by the Board’s

People and Culture Committee, with support from our Global Head of People &

Culture, Executive Team, people leaders and external consultants.

EMPLOYEE ENGAGEMENT

As a purpose-led organization, we are committed to building an inclusive, values-

driven culture where all our people feel supported to grow, contribute and succeed.

This culture is essential to attracting and retaining top talent, as well as fostering

wellbeing and long-term engagement.

We work hard to ensure our employees connect with our organizational purpose,

values and strategic priorities, ensuring they understand how their roles contribute to

our broader success. We measure success in achieving this through our key metrics

of employee engagement and turnover. In FY 24 our employee engagement survey

found 79.6% of Pacific Edge people reported satisfaction in their roles; and >80%

of Pacific Edge people reported a clear understanding of the company’s vision and

purpose.

Due to a change in the timing of the annual engagement survey, the next update of

employee engagement metrics will be provided in the FY 26 annual report.

Our values guide our daily actions and are central to how we work.

Our Values

PUT PATIENTS

FIRST IN EVERYTHING

WE DO

ARE COMMITTED TO

CUSTOMER SUCCESS

ARE GUIDED BY

DATA & EVIDENCE

WE CELEBRATE

SUCCESSES, LARGE

AND SMALL

SUPPORT OUR

TEAMMATES

ARE TRANSPARENT

AND TRUSTING

SUSTAINABILITY

28

29

BUILDING OUR CAPABILITY
Developing Skills and Careers

We continue to invest in our peoples’ careers and capability to support the growth and sustainability of our

business.

Our learning and development (L&D) strategy is designed to help attract and retain top talent, while also

ensuring that we build the specialist skills and institutional knowledge we need to respond to a rapidly

evolving environment.

We recognize that some technical areas central to our work — such as uro-oncology, genomics, digital

innovation and clinical operations — are challenging to recruit externally. As a result, we take a proactive

approach to building these skills internally.

Over the past year we have provided leadership training courses for our emerging leaders and training in

new molecular biology assay techniques and ISO Quality System Management (ISO15189:2022). Cross-

training opportunities between our US and New Zealand laboratory teams continue to be a valuable tool for

building a more flexible and knowledgeable workforce.

In the US, our Hershey-based team participated in an externally-facilitated performance excellence course,

led by a certified LEAN 6-Sigma “Black–Belt” moderator. This program has empowered the team to drive

continuous improvement using a similar data-driven approach to that used by our New Zealand team.

Participants developed skills in problem identification, performance measurement, data analysis, and

solution implementation. They also gained insights into Lean Operations, such as waste elimination; process

mapping; process optimization for enhanced efficiency and customer satisfaction; and the importance of

fostering a clean, organized, and efficient work environment.

We are already seeing tangible benefits from this program, including increased productivity, streamlined

processes, and improved safety outcomes.

Educational Collaboration

We continue to collaborate with educational institutions to build awareness of Pacific Edge and attract talent

into our business. Our partnership with the University of Otago is broad-ranging, including participation in

recruitment fairs and internships for STEM students.

As part of our contribution to the Medical Laboratory Sciences (MLS) faculty, we offer student placements

that provide real-world exposure to a commercial diagnostic laboratory. These placements allow

undergraduate and honours students to observe the operations of a molecular diagnostic laboratory and

complete research projects in a live laboratory environment.

We also support the assessment of student performance and create opportunities for students to connect

with practicing medical laboratory scientists — something that is rare outside of hospital or academic settings

in New Zealand.

Offering Real World Experience

To build a strong pipeline of future talent, we operate an internship program in partnership with Callaghan

Innovation and the University of Otago. Each year, we select interns from a variety of academic backgrounds

— such as biomolecular science, clinical studies, biostatistics or information science — to work on focused

projects that address real challenges within our business.

Interns spend 400 hours in project teams, gaining hands-on experience with real-world data and

contributing to technical, digital, data architecture or reporting solutions. This year we expanded the

program to include projects hosted in our commercial laboratories.

SUSTAINABILITY

30

These internships not only give students valuable industry experience but also open up alternative career
paths within commercial diagnostics, an option that many MLS and STEM students - who traditionally view

hospital/academic labs as their next career step - may not have considered. For Pacific Edge, the program

serves as a valuable talent pipeline, and we have typically offered permanent employment to at least one

intern each year.

Total Rewards

Pacific Edge’s Total Rewards framework is a key component of our strategy to attract, retain and recognize

talent. Our Total Rewards practices are overseen by the Board’s People and Culture Committee to ensure it

remains competitive and fit for purpose.

Details of our Total Rewards practices are provided in the dedicated section on pages 67-68 of this report.

A DIVERSE WORKPLACE

At Pacific Edge, we seek to create a culture where diversity, equity and inclusion are actively supported and

embedded in our day-to-day operations. We know that a flexible, inclusive environment not only enables our

people to grow and thrive — it also drives better business outcomes.

Our recruitment, development, talent and succession planning practices are grounded in the principles

of equal opportunity and guided by our Diversity Policy. These principles are applied at all levels of the

organization.

While we hire based on capability and fit for the role, team and business, we also value diverse thinking,

backgrounds and abilities. Our recruitment and Total Rewards practices are designed to be inclusive and

free from bias, and we continuously look for ways to improve how we can attract and support a diverse

range of talent.

Pacific Edge’s Gender Diversity

31 March 2025

Male

(FTE)

31 March 2025

Female

(FTE)

31 March 2025

Not Specified

(FTE)

31 March 2024

Male

(FTE)

31 March 2024

Female

(FTE)

Directors4 (67%)2 (33%)0 (0%)5 (71%)2 (29%)

Officers

*

7 (88%)1 (12%)0 (0%)8 (100%)0 (0%)

Extended leadership team

including Officers

15 (79%)4 (21%)0 (0%)14 (78%)4 (22%)

Total team58 (50%)57 (49%)1 (1%)49 (49%)51 (51%)

Figures in brackets represent the proportion of the team

* Includes the CEO

Encouraging a Gender-Diverse Workforce

While Pacific Edge’s workforce is largely gender-balanced overall, we recognize the current under-

representation of women in senior leadership and Board roles. We continue to identify opportunities to

improve diversity at all levels of the organization, ensuring our teams reflect a wide range of perspectives

and experiences.

SUSTAINABILITY

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

31

CELEBRATING OUR DIFFERENCES
Recognizing and celebrating the differences that make us unique helps foster a shared sense of purpose

and values across the organization, as well as strengthening the culture that supports our growth and the

commitments we make to all our stakeholders.

Across our teams in New Zealand and the US, we celebrate days fundamental to our team’s diverse cultural

identities, including Waitangi, Matariki, Diwali and St Patrick's Day. These celebrations are more than

symbolic — they reflect our commitment to inclusion and shared understanding.

We also take a strong stance on mental health and inclusivity. Initiatives such as Pink Shirt Day help us

celebrate working together to stop bullying, and to reinforce inclusiveness, kindness and respect. These

events are often paired with practical initiatives, including mental health first aider training for health and

safety representatives, and cultural exchanges between our US and New Zealand teams.

FOSTERING HEALTH, SAFETY AND WELLBEING

We are committed to providing safe and healthy workplace practices

for all, and ensuring that no one is harmed at work. Our Health

and Safety Policy outlines a clear goal: to eliminate as far as

reasonably practicable, all injuries, accidents, and incidents from

the workplace.

We maintain rigorous safety practices across the business,

and require active participation from our people to ensure

procedures are clearly understood and followed. These include:

• Company-wide safety training each quarter

• Regular Toolbox Talks focused on specific safety topics

• Twice-yearly audits of our health and safety practices

We have a strong record of delivering on our commitments. From

November 2024 to February 2025, our Health, Safety and Wellbeing

framework underwent an independent review. The findings were

positive, with the auditors highlighting our clear commitment to compliance,

continuous improvement and employee wellbeing. In their words:

“...Pacific Edge prioritizes its Health & Safety (H&S) obligations and maintains a strong focus on continual

improvement... A comprehensive H&S framework ensures compliance with relevant legislation, industry

standards, and best practices. Regular reviews and updates of policies, procedures, and Standard

Operating Procedures (SOPs) demonstrate a proactive approach to risk management and employee

wellbeing.”

Our health and safety activities are overseen by two internal committees (APAC and US), both chaired by

the Chief Operating Officer. Updates are provided at every Board meeting. Further detail is covered in the

company’s governance statement in this report.

Supporting Mental Health and Wellbeing

We want every employee to feel supported and empowered in their role. Our mental health and wellbeing

program is a key part of this, offering the tools and environment our people need to perform at their best

and maintain their wellbeing.

This year, we continued to invest in mental health initiatives, including:

• Independent employee assistance services, tracked monthly

• Training, including Mental Health Toolbox Talks

• Awareness training for health and safety committee members

• Completion of the LivingWorks ASSIST mental health program by 19 team members.

These actions reflect our long-term commitment to creating a workplace where people can thrive,

personally and professionally.

SUSTAINABILITY

"In FY 25,

we are pleased to

report zero lost time

injuries across both

our New Zealand

and US operations

— a reflection of our

commitment and the

engagement of our

people."

32

RESPONSIBLE SUPPLY CHAIN
STRENGTHENING SUPPLIER RELATIONSHIPS

Following a detailed supplier review in FY 24 by an internal specialist, a number of initiatives were

introduced and embedded in FY 25. Quality agreements and supply agreements have been revised,

updated and implemented across the supplier network, and a program of supplier audits is underway.

Quarterly reviews are held with all strategic suppliers, and we have also launched new supplier evaluation

questionnaires. This has led to improved communications and clarity of expectations with suppliers.

Supplier alignment with Pacific Edge’s own policies and values is very important to us. We have taken steps

to ensure that our key suppliers demonstrate respect for human rights and ethical labor practices. This

includes requiring suppliers to commit to eliminating modern slavery — such as forced labor or child labor —

and adopting appropriate human rights policies and procedures.

SUPPORTING OUR COMMUNITIES

We believe it is important to support the communities in which we live and operate. We do

this by collaborating with patient organizations at the forefront of cancer advocacy and care,

and through team participation in support of local charities and health-related initiatives

designed to fundraise and educate.

GIVING PATIENTS A VOICE AND RAISING BLADDER CANCER AWARENESS

An awareness of bladder cancer and available test options empowers patients to take a more informed and

active role in their care. To this end, we partner with leading bladder cancer advocacy organizations and

support key global advocacy events.

The Bladder Cancer Advocacy Network (BCAN) is the leading bladder cancer patient organisation in the US

and is focused on increasing awareness of bladder cancer and its care, building a supportive community of

people impacted by the disease, funding educational and support programs, and advancing bladder cancer

research. In recent years our collaboration with BCAN has included sponsorship, participation in thought

leadership events like Think Tank, and the co-development of leading patient resources, including patient

handbooks and factsheets.

Each year we also support Bladder Cancer Awareness Month in May, a time for those affected by bladder

cancer to stand together and raise awareness of the disease while working to better support its early

detection, treatment and care. Over

the last several years our activities

in May have emphasized the

importance of regular monitoring

and compliance with scheduled

checks, while raising awareness of

Cxbladder as a non-invasive bladder

cancer surveillance alternative.

As part of Bladder Cancer

Awareness Month each year our

team also take part in a range of

social initiatives. Traditionally this

includes a themed dress-up to help

increase the profile of the event and

as a team building exercise.

SUSTAINABILITY

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

33

SUPPORTING CAUSES MEANINGFUL TO OUR PEOPLE
Pacific Edge team members are encouraged to promote causes meaningful to them, across the

organization. Below are some examples of causes we have supported in the last year.

Movember

Founded in 2003, the Movember Foundation works to raise awareness of men’s health issues and fund

related projects around the world, with a specific focus on testicular cancer, prostate cancer, mental health

and suicide prevention. To date the Foundation has raised over NZ $1 billion globally. We support its

efforts each November, both though promoting broader awareness of the initiative and through team and

individual fundraising efforts.

Relay For Life

An inspiring event that runs throughout New Zealand,

Relay for Life gives communities a chance to celebrate those

who have or have had cancer and the people who care for

them. It also remembers loved ones lost to the disease and

encourages communities to join the fight against cancer by

raising awareness and funds for the New Zealand Cancer

Society. In 2025, a Pacific Edge team of over 20 staff and

their families participated in the Otago Students Relay for

Life which ran overnight for 12 hours around the University

of Otago campus in late March. The Otago Students Relay

raised over $100,000 in support of the Cancer Society's

supportive care services, education programs, prevention

policies, and life-saving research.

Pink Shirt Day

Pink Shirt Day is an annual event against bullying held in Canada, New Zealand and Germany. The Mental

Health Foundation of New Zealand (MHFNZ) has run the campaign in New Zealand since 2012, encouraging

participating individuals, groups, schools and workplaces to wear pink and attend or host informative events

designed to raise awareness and stop bullying, while promoting kindness and inclusivity.

Cocoa Packs

The Pacific Edge team in Hershey, Pennsylvania volunteer with Cocoa Packs, a non-profit that provides food

assistance and other services to enhance the wellbeing of local children. Cocoa Packs currently provides

weekly support to over 1,400 individuals.

SUSTAINABILITY

34

SUSTAINABILITY
OUR ENVIRONMENTAL IMPACT

USING OUR RESOURCES RESPONSIBLY

Our Environmentally Sustainable Procurement Policy sets out our commitment to the responsible

purchasing of materials, goods and services, including three basic principles. Prior to purchasing any goods

or services we must ensure the following:

• that the item needs to be purchased i.e. there are no other suitable items already available within the

company;

• that the lifecycle impacts of the item are considered, including processes used to create it,

environmental impacts when used and what happens at the end of its life; and

• that relevant environmental information is provided by the supplier.

In FY 24, we began recording carbon emissions associated with all material aspects of our business,

including the transportation of inventory to and from Pacific Edge. This benchmark information has enabled

us to develop targets and strategies to reduce carbon emissions associated with consumables as well as the

environmental impact of waste, including disposable plastics and chemical waste. We describe our progress

in our FY 25 climate-related disclosures and in the summary on page 25.

CLIMATE-RELATED DISCLOSURES

FY 25 was Pacific Edge’s second year of mandatory reporting under the Aotearoa New Zealand Climate

Standards. Click here to access the full report, which is also on our website.

The following summary outlines how we are positioning ourselves for a low-emissions, climate-resilient

future (our Transition Plan) as well as how we progressed towards our emissions reduction targets in FY 25.

POSITIONING OURSELVES FOR A LOW-EMISSIONS FUTURE

Pacific Edge’s carbon emissions primarily result from the logistics involved with transporting Cxbladder kits

to and from collection points, as well as from travel undertaken by the sales team to service and support

clinicians. International travel between the United States and New Zealand, along with domestic travel across

target markets, also contributes significantly to Pacific Edge’s carbon emissions.

Figure 1 provides a graphic representation of how our carbon emissions relate to the various functions

across our business.

While we acknowledge the emissions generated by our current business model, particularly through the

transportation of samples to centralized laboratories, we believe that the overall carbon footprint of the

Cxbladder diagnostic pathway is lower than the existing standard of care, which relies heavily on cystoscopy

and in-clinic procedures.

This belief is supported by a study carried out in FY 25, in collaboration with Te Whatu Ora — Health

New Zealand Waitaha Canterbury and Toitū Envirocare. The study assessed the GHG emissions impact

of incorporating Cxbladder into a revised standard of care for bladder cancer diagnosis, compared to the

existing standard of care. The findings show that the Cxbladder diagnostic pathway can reduce emissions

by 40% against the existing standard of care, highlighting the potential for clinical innovation to help reduce

emissions.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

35

Figure 1: Relationship between Pacific Edge emissions and key functions across the business
Our Transition Plan

We are implementing a number of strategic initiatives aimed at positioning Pacific Edge for a low-emissions,

climate-resilient future. By focusing on greater efficiency in test result delivery and increasing the adoption

and use of Cxbladder tests, we aim to achieve both financial gains and a reduction in carbon intensity per

test. This strategic alignment ensures that capital deployment and funding decisions support our strategic

priorities.

A description of these initiatives and how they will mitigate the impacts of climate change, is provided

on pages 10 to 13 of our climate-related disclosures. Figure 2 summarizes the key elements of our

transition plan.

RESEARCH AND

DEVELOPMENT

Developing IP that

addresses unmet

clinical needs in

bladder cancer

diagnosis and

management by

delivering non-

invasive genomic

biomarker tests which

allow early detection

and clinically

actionable care.

Emissions relate to

freight and research

laboratory in Dunedin,

NZ.

CLINICAL

EVIDENCE


Building robust

clinical evidence that

provides catalysts for

guidelines inclusion

and reimbursement.

Emissions relate to

freight of samples,

travel to study

locations, and staff

located in US, NZ and

AUS.

SALES AND

SUPPORT

95% of revenue is

generated from the

Unites States, with

Account Executives

based close to the

clinicians across the

US. Sales and support

are also based in New

Zealand, Australia

and South East Asia.

Emissions relate to

travel and support of

Account Executives.

TEST DELIVERY

Laboratories based

in Hershey, US and

Dunedin, NZ process

tests and send results.

Emissions relate

to operating the

laboratories in

Dunedin, NZ and

Hershey, US.

GENERATED BY

LABS AND OFFICES

IN DUNEDIN AND

HERSHEY

19%

GENERATED

BY EMPLOYEE

TRAVEL

70%

GENERATED BY

MOVEMENT OF

INVENTORY,


TEST KITS AND

SAMPLES

11%

SUSTAINABILITY

36

SUSTAINABILITY
TEST KIT

MANUFACTURE

PRODUCT

DISTRIBUTION

TEST KIT USE,

SAMPLES TO

LABORATORIES

LABORATORY


TESTING

INFORMATION

SHARING

EMPLOYEE AND

BUSINESS TRAVEL,

SALES & OFFICE

SUPPORT, R&D

PRODUCT

SIMPLIFICATION

INITIATIVES:


Localised testing

(ultimate goal IVD

test kit)


Reduced time to

test results


RNA stabilisation

resulting in fewer

re-tests and sample

rejects (R&D)

TARGETS & FUTURE

ACTIONS:


Improved carbon

intensity per test


Testing closer to

patients locations

CAPITAL DEPLOYMENT:


Resource allocation

underpinned by

business plan and

R&D roadmap

TESTING

AUTOMATION

INITIATIVES:


Increased

automation of test

performance


Processes involving

lower use of

hazardous chemicals

and increased tests

per plate


Processes involving

less single use

plastics


Green Lab initiatives

TARGETS & FUTURE

ACTIONS:


Improved carbon

intensity per test

CAPITAL DEPLOYMENT:


Resource allocation

underpinned by

business plan and

R&D roadmap

SUPPLIER

ENGAGEMENT

INITIATIVES:


Supplier

diversification or

multi-site suppliers


Reagent

manufacture in US


Shipping reduction

to lower/ eliminate

the need for dry ice


Improved buffer

performance to

increase kit shelf life

and sample shipping

and processing

timeframes

TARGETS & FUTURE

ACTIONS:


Improved carbon

intensity per test

CAPITAL DEPLOYMENT:


Resource allocation

underpinned by

business plan and

R&D roadmap

OPERATING

EFFICIENCY

INITIATIVES:


Increased tests per

clinician


Freight efficiency,

with increased

number of samples

sent per package


Carbon impact

study – a tool

to demonstrate

emissions advantage

and support

increased demand

TARGETS & FUTURE

ACTIONS:


Improved carbon

intensity per test


Improved carbon

intensity per FTE

CAPITAL DEPLOYMENT:


Resource allocation

underpinned by

business plan and

R&D roadmap

Figure 2: Transition Plan summary

Value Chain

Transition Plan Key Initiatives

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

37

FY 25 EMISSIONS SUMMARY
FY 25 was Pacific Edge’s second year of greenhouse gas (GHG) emissions measurement for our operations,

with FY 24 providing the baseline for comparative analysis.

Overview of Emissions

As a global cancer diagnostics company, our emissions profile is relatively small. In FY 25, travel and freight

was by far the largest contributor, accounting for 80.8% of all emissions (82.1% of all emissions for FY 24).

Due to the specialized nature of cancer diagnostic tests, in-person support and training remain essential

for clinicians and patients, making travel unavoidable in many instances. Most staff travel, including air

travel and business travel in non-company owned vehicles, is attributed to our Sales team (supporting and

growing the use of Cxbladder) and Clinical Studies team (for study site visits to build our clinical evidence

portfolio).

Air freight is primarily used to transport test kit components from suppliers to our laboratories; to ship test

kits to customers; and to return samples from customers for processing. Business travel has been identified

as a key area for improving emissions efficiency.

The next largest contributor of emissions was indirect GHG emissions from consumption of purchased

electricity (Scope 2) in respect of our Dunedin and Hershey locations. Scope 1 comprises refrigerants used

for laboratory equipment, which did not require replenishment during FY 25 or FY 24.

Table 1: Emissions Summary

Scope

1

Emissions sourcesDescriptionFY 25

(tCO

2

e)

FY 24

(tCO

2

e)

Scope 1Direct emissions Refrigerants 0.000.00

Scope 2Indirect emissions from

imported energy

Electricity – location-based method

128.04145.39

Scope 3Other indirect emissions Air travel, air freight, road freight, shipping

freight, business travel in non-company

owned vehicles, accommodation,

employee commuting, working from home,

decontamination of medical waste, incineration

of clinical waste, electricity distributed

transmission and distribution losses, general

waste, dry ice

804.85963.89

TOTAL932.891,109.28

Total direct emissions0.000.00

Total indirect emissions932.891,109.28

Total gross emissions932.891,109.28

Direct emissions removals0.000.00

Purchase emission reductions0.000.00

Total net emissions932.891,109.28

Test throughput28,89432,633

Average FTE112113

Emissions intensity

Gross emissions / test (unit)0.0320.034

Gross emissions / FTE8.34 9.82

1

The Scope 1 Direct emissions and Scope 2 Indirect emissions from imported energy (location based) for 2025 (tCo

2

e) have been subject to independent

limited assurance by PwC. The Scope 3 emissions data for 2025, and the emissions intensity for 2025 are not subject to assurance. The 2024 emissions

data for Scope 1, Scope 2, and Scope 3 and the emissions intensity for 2024 have not been subject to independent assurance by PwC.

SUSTAINABILITY

38

Progress Against Target
Pacific Edge has set a 5-year target of a 20% reduction in emissions intensity (GHG emissions per test

throughput) by end FY 29.

In FY 25 (our first year) we achieved a 5.9% reduction in emissions intensity, lowering the total emissions per

test from 0.034 tCO2e in FY 24 to 0.032 tCO2e in FY 25. This progress is summarized in Table 1, reflecting

the early success of our transition plan and reinforcing that meaningful emissions reductions can be

achieved without compromising our broader goal.

Looking Ahead

We expect staff air travel and business travel in non-company-owned vehicles to rise in the short to medium

term as we work to expand test throughput and fulfil the unmet need for a diagnostics tool that assists in

the detection and treatment of bladder cancer. While the increasing size of our team will likely drive higher

absolute emissions, our focus on improving sales team efficiency — specifically, increasing the number of

tests per physician — is expected to reduce GHG emissions intensity per test.

Air freight is also projected to grow in the short term as we focus on increasing test throughput. However,

once a critical mass is reached, we anticipate opportunities to improve efficiency in procurement,

distribution and sample return logistics. These efficiencies are expected to reduce emissions intensity

over time.

Further information is provided in the climate-related disclosures.

SUSTAINABILITY

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

39

OUR GOVERNANCE PRACTICES
Strong governance is fundamental to the performance of Pacific Edge. Our Board is

ultimately responsible for ensuring that the Company and its subsidiaries maintain high

ethical standards and corporate governance practices

We are committed to maintaining the highest standards of governance. We ensure that our corporate

governance practices are in line with best practice; the NZX Corporate Governance Code (NZX Code); and

broader expectations of corporate behavior. Over the last year we have continued to evolve our governance

framework with the following initiatives.

• Ensuring compliance with the new mandatory reporting requirements of the Aotearoa New Zealand

Climate standards and more broadly the integration of environmental and social considerations into the

framework

• Completing the implementation of our risk framework and risk assessment practices across the entire

business

• Working with our advisors to understand the IRD’s requirements in respect of Tax Governance,

completing an assessment of our tax framework and implementing improvements; and better managing

the tax risks emerging with our growth in international markets

• Strengthening our stakeholder engagement practices, ensuring that investors and other stakeholders

are informed about our progress and any market developments in a timely manner

The key corporate governance documents referred to in this report are available on the governance section

of Pacific Edge’s website.

GOVERNANCE INITIATIVES AND HIGHLIGHTS

Risk Management

Our risk management approach is described in the Corporate Governance Statement and the Risk Analysis

and Management section respectively on pages 46 to 56 and pages 57 to 62 of this report. We have a

comprehensive risk management framework. We have embedded Failure Modes and Effect Analysis

(FMEA) across our business. It is the tool of choice to assess and manage risks, including quality, health and

safety, market-related and climate-related risks. We assess and prioritize risks using Risk Priority Numbering

(RPN) and heat maps from every department leader for every Board reporting cycle. We have also

benchmarked our tax risk management framework against better practice to cover the risks emerging from

our growth trajectory and advanced our assessment of climate risks in line with the Aotearoa New Zealand

Climate standards.

Risk management is embedded in everyday practices, which include regular internal and external audits,

training, quality management systems, risk reporting and promotion of a strong risk culture, which is

promoted as ‘Say what we do and do what we say’. Company-wide training is undertaken to ensure staff are

adept in the use of risk management tools.

GOVERNANCE

40

GOVERNANCE
Operational Quality and Compliance

As a health provider, Pacific Edge is required to meet stringent regulatory, quality, health and safety and

manufacturing standards in every country we are operating in.

We operate a Quality Management System (QMS) that encompasses manufacturing, laboratory operations,

clinical science and digital development. Our QMS is administered through iPassport, which maintains

standard operating procedures, tracks quality metrics such as Non-Conformances, CAPAs (Corrective

and Preventive Actions), Change Controls and ensures compliance with our ISO9001/ISO13485/ISO15189

requirements.

This, combined with a program of internal and external audits, enables the company to meet its quality

commitment to being ‘audit ready everyday’. In the past year we conducted 10 internal QMS audits, which

have been assessed by external auditors from CLIA, CAP, Telarc and IANZ and have also partnered with

SeerPharma to ensure compliance with ISO13485 and FDA requirements. All our major suppliers are required

to sign a Quality Agreement that governs how incidents or other non-conformances are governed between

our companies.

Below is a summary of our operating standards:

• all Group business operations are governed by ISO-9001;

• our US laboratory operations are governed by CAP

1

, CLIA

2

, GLP

3

and NYS

4

;

• our New Zealand laboratory operations are governed by CLIA, Medical Laboratory Council and ISO-

15189;

• digital/Software for lab operations is governed by CLIA, NYS, ISO-15189, HIPAA

5

and IT Security;

• Pacific Edge manufacturing is governed by the principles of Good Manufacturing Practices (GMP)

(internally audited);

• Pacific Edge collection devices are registered with the TGA

6

in Australia, their manufacturing follows

GMP and is manufactured and supplied in accordance with ISO-13485; and

• Pacific Edge clinical evidence generation is governed under GCP (good clinical practice) and IRB ethics

approvals. Clinical Sciences are working towards future compliance with ISO20916.

A new Quality Policy was implemented in FY 25, supporting the extension of the QMS to ISO-13485/

ISO14971 requirements. Certification for compliance with ISO 13845:2016 has since been granted.

1

College of American Pathologists

2

Clinical Laboratory Improvement Amendments (Centers for Medicare & Medicaid Services)

3

Good Laboratory Practice

4

New York State (Department of Health)

5

Health Insurance Portability and Accountability Act (US)

6

Therapeutic Goods Administration

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

41

Chris Gallaher
Chairman and Independent

Director

(Appointed 2016)

Chris joined the Board in 2016

and was appointed as Chairman

in August 2016. A New Zealand

citizen resident in Melbourne,

Chris has held senior positions

in both CEO and CFO roles with

a number of large international

companies and was a partner

in Arthur Young, Chartered

Accountants. Prior to retiring

from full time corporate life,

he was CFO of Fulton Hogan,

a large NZ resources based

civil contractor. Chris holds a

BCom from Otago University,

is a Chartered Accountant,

a member of the Australian

Institute of Company Directors,

is Chairman of Link Group

Holdings Ltd, Carisbrook

Holdings Ltd and Mariposa

Holdings Ltd and Director of

Highlanders Rugby Club and

Good Shepherd Australia and

New Zealand.

Anatole Masfen

Independent Director

(Appointed 2008)

Anatole is the co-founder

of Artemis Capital, a private

equity investment firm based in

Auckland. He graduated from

the University of Auckland with

an MCom (Hons) in Finance and

Economics. Following that he

spent eight years with Air New

Zealand (and later the merged

entity with Ansett Australia)

holding senior positions in

Pricing, Revenue Management

and Systems implementation.

He holds directorships in

numerous private companies

and has significant knowledge

of financial capital markets.

As a long standing director of

PEB and investor in numerous

medical and tech companies,

Anatole has a detailed

knowledge of the medical

sector and future trends. In

particular human sciences and

disruptive technologies.

Sarah Park

Independent Director

(Appointed 2018)

Sarah is the co-founder of

Even Capital, a pioneering

venture capital firm 100%

focused on investing in female

entrepreneurs in New Zealand

and Australia. As an investor,

Sarah has a passion for early

stage businesses building world-

changing technologies. Sarah

brings 25+ years international

corporate finance and capital

markets experience to Pacific

Edge after a professional career

with PwC in NZ and HSBC

Investment Bank in London.

During her executive career,

Sarah held a wide variety of

roles including advising on M&A

and capital market transactions,

managing family office

investments, and as a sell-side

Equity Research Analyst. Sarah

is Deputy Chair of National

Provident Fund, and a Director

of NZ med-tech company,

Orbis Diagnostics. Sarah has a

MA(Hons) in Economics from

the University of Edinburgh

and is a member of the New

Zealand Institute of Directors

and Chapter Zero NZ.

PACIFIC EDGE’S BOARD

BOARD AND MANAGEMENT

42

Bryan Williams
Independent Director

(Appointed 2013)

Bryan is an internationally

recognised cancer researcher

and research administrator, with

significant business experience.

He has held a number of

governance roles, including

with a NASDAQ listed biotech

company. Presently, he serves

on the boards of two Australian

and one American privately

held biotechnology companies.

He is also a co-founder of

an American biotechnology

company. Bryan was Director

and CEO of the Hudson Institute

of Medical Research. He is

currently Emeritus Director and

Distinguished Scientist at the

Hudson Institute in Melbourne.

He has a BSc (Hons) and

PhD in Microbiology from the

University of Otago.

Anna Stove

Independent Director and

Chair of the People and Culture

Committee

(Appointed 2021)

Anna has a successful track

record in leading and driving

transformational change within

the Healthcare sector. She

has significant gobal business

experience having held a variety

of senior executive roles within

Asia Pacific and Europe. Prior to

stepping down from corporate

life, Anna was the NZ General

Manager of GlaxoSmthKline. She

is now committed to growing

businesses through best

practice governance. Anna also

Chair’s Rua Bioscience.

Tony Barclay

Independent Director and Chair

of Audit and Risk Committee

(Appointed 2022)

Tony brings over 30 years

experience in business and 22

years healthcare experience.

Tony was CFO at medical

device company Fisher & Paykel

Healthcare from the time of

separation from Fisher & Paykel

Appliances in 2001 until retiring

from full-time employment in

2018. Prior to Fisher & Paykel

Healthcare Tony worked for

PriceWaterhouse and Arnott's

Biscuits in finance roles. Tony is

also a board member of listed

company Rua Bioscience and

holds a number of directorships

in private companies, all in

MedTech. Tony holds a BCom

from the University of Otago

and is a Chartered Accountant

and a member of the New

Zealand Institute of Directors

and INFINZ.

BOARD AND MANAGEMENT

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

43

Dr Peter Meintjes
CEO, Pacific Edge

Peter is a molecular

diagnostics and genomics

leader focused on nascent

market development of

disruptive innovations to drive

commercial success. Prior to

joining Pacific Edge, he was

based in Boston, USA for a number of molecular

diagnostic leadership roles. Most recently the

Chief Commercial Officer at Eurofins Transplant

Genomics (TGI), a transplant diagnostics company

focused on revolutionizing post-transplant care

for kidney transplant recipients with non-invasive

biomarkers. He was responsible for scaling the

commercial team behind TruGraf (now OmniGraf),

the only CMS-reimbursed test for subclinical

organ rejection. Prior to TGI, Peter was CEO at

Omixon Inc, a molecular diagnostics company

focused on the pre-transplant market, world

leader in HLA typing by NGS, and recipient of the

Innovation Grand Prize among all companies in

Hungary in 2018. Omixon was acquired by Werfen

in 2024. Prior to his US career, Peter worked

at Auckland-based Biomatters, the creators of

Geneious — software specializing in translating

genetic and genomic data into biological insights

for researchers and medical insights for clinicians.

Biomatters was acquired by GraphPad in 2019.

Grant Gibson

Chief Financial Officer,

Pacific Edge

Grant is an experienced

financial executive and

chartered accountant, who

brings significant financial

experience to the role. Prior

to joining Pacific Edge in late

2019, Grant was Chief Financial and Operating

Officer for Dunedin-based company, TracMap,

where he was responsible for leading the financial

management and operations across the company.

Prior to that, Grant worked in executive finance

roles at Westpac, including as Head of Finance

for Westpac New Zealand. During his time with

Westpac, he headed the finance team for New

Zealand's largest financial transaction, the local

incorporation of Westpac New Zealand.

Tamer Aboushwareb MD PhD

Chief Medical Officer,

Pacific Edge

Tamer joined Pacific Edge

in June 2022 and brings to

the company a depth of

experience in clinical, medical

research, and commercial

roles in urological medicine in

Egypt and the USA. Prior to joining the company,

he was Senior Director of Oncology Clinical

Development at Exact Sciences and prior to

that he was Global Therapy Area Head, Urology,

Medical Affairs at the global pharmaceutical

company Allergan. He is a graduate of the Ain

Shams University Medical School in Cairo. He also

holds Masters and Doctoral degrees in urology and

molecular medicine and has held residency, post-

doctoral and research roles in Egypt and the US.

Darrell Morgan

Chief Operating Officer,

Pacific Edge

Darrell has nearly 40

years experience in senior

roles in pharmaceutical

research and development,

immunodiagnostics, and

device development for

drug delivery across human and animal health,

technical operations and customer-facing roles

in the UK, Europe and New Zealand. Prior to

joining Pacific Edge, Darrell held several roles at

Argenta, an Auckland based animal pharmaceutical

manufacturer, including VP of Business

Development, Head of Global Pharmaceutical

Sciences and Director of Product Development.

His last role in Europe was leading UCB’s large

molecule sterile drug delivery and patient solution

technologies teams, developing drug/device

combination products which were approved by

both FDA and EMEA.

PACIFIC EDGE’S SENIOR MANGEMENT TEAM

BOARD AND MANAGEMENT

44

Justin Harvey PhD
Chief Technology Officer,

Pacific Edge

Justin joined Pacific Edge

in 2004, bringing a robust

background in medical

laboratory testing, diagnostics,

and cancer genetics. He

has played a pivotal role in

the development and commercialization of the

Cxbladder suite of products from their inception.

Currently, Justin leads Pacific Edge’s scientific

Research and Development program, focusing on

developing novel products aimed at improving

patient outcomes through early detection and

management of cancer. Justin is dedicated to

advancing medical science and improving patient

care through innovative diagnostic solutions. His

leadership and expertise continue to drive Pacific

Edge’s mission to provide leading solutions for the

early detection and management of cancer.

Professor Parry Guilford

Chief Scientific Officer,

Pacific Edge

Parry has led the science,

research and development

at Pacific Edge from its early

days. As one of the founding

scientists and a member of

the Scientific Advisory Board

of the Company, Parry is the architect of many of

the Company’s product prototypes. Parry’s focus is

to bring his world class skills and experience on the

step change in biotechnology for the Company’s

next generation of products.

David Levison

President, Pacific Edge

Diagnostics USA

David has spent more than

25 years in the healthcare

industry, working across

a range of sectors from

pharmaceuticals to services

and diagnostics. He has

been the founder, CEO, and Board member of a

number of high growth medical technology and

molecular diagnostic businesses in the US as well

as working in private equity. David served for four

years as a member of the Pacific Edge Board of

Directors, before transitioning to lead the PEDUSA

organization in November of 2020 as Executive

Chairman of PEDUSA and then as President

beginning September 1, 2022.

Glen Costin

President APAC, Pacific Edge

Glen joined Pacific Edge in

April 2023 having spent more

than 20 years in Asia Pacific

markets with life science/

diagnostic companies such as

BD (Becton Dickinson) and

Bio-Rad Laboratories. Glen

has had extensive hands-on commercial and go-

to-market experience in China, Korea, Taiwan, SE

Asian countries, Australia and New Zealand both

directly and via distribution partners. His sales and

marketing experience spans, life science research,

diagnostic instrumentation, as well as launching a

new Oncology test for Cervical Cancer Screening

generating over US$38M pa in revenues within

APAC. Glen has sold at the executive level for many

years and developed Key Opinion Leader networks

to support innovative technology introduction in

the medical diagnostics sector, including his former

role as Global Private Pathology Director at BD

Diagnostics. Glen’s qualifications include: Bachelor

of Science (Genomics), Masters of Management

(Marketing Management & Finance) from

Macquarie Graduate School of Management.

Zoe O’Donnell

Global Head of People &

Culture, Pacific Edge

Zoe joined Pacific Edge in

January 2025 as Global Head

of People & Culture. Prior

to joining Pacific Edge Zoe

worked in a number of roles

and industries in the UK and

New Zealand most recently with Fisher & Paykel

Appliances as Global Total Rewards Consultant.

Zoe’s roles and experiences gives her a unique

breadth and depth to her HR and Leadership

expertise. As Global Head of People & Culture

Zoe’s passionate about people and performance

and leads the people strategy and initiatives

that streamline and enhance all touchpoints

of the employee lifecycle and experience. Zoe

champions an equitable and inclusive culture and

believes in building organisational capability and

accountability to drive a high-performance culture

aligned to strategy while delivering value to our

customers.

BOARD AND MANAGEMENT

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

45

GOVERNANCE
46

Strong governance is fundamental to the performance of Pacific Edge Limited and Pacific Edge’s Board is
ultimately responsible for ensuring that the Company and its subsidiaries (the Group) maintain high ethical

standards and corporate governance practices.

Pacific Edge is committed to maintaining the highest standards of governance. It does this by ensuring

that its corporate governance practices are in line with best practice and the NZX Corporate Governance

Code (NZX Code). The Board believes that for FY 25, Pacific Edge’s governance practices are appropriately

aligned with the NZX Code.

The key corporate governance documents referred to in this report are available on the goverance section

of Pacific Edge’s website.

PRINCIPLE 1: CODE OF ETHICAL BEHAVIOUR

“Directors should set high standards of ethical behaviour, model this behaviour and hold management

accountable for these standards being followed throughout the organisation.”

CODE OF ETHICS

Pacific Edge maintains high standards of ethical behaviour and has both a Directors’ Code of Ethics and

an Ethical Behaviour Policy for employees of the Company, setting out the standards that each Director or

employee must adhere to whilst conducting their duties. The Code and Policy are reviewed every two years.

General principles within both Policies include (but are not limited to) requiring all Directors and employees

to:

• act honestly and with personal integrity in all actions;

• in the case of Directors, give proper attention to the matters before them and exercise their powers and

duties with a due degree of care and diligence;

• not make improper use of information acquired as a Director or employee, or of assets or resources of

the Company; and

• comply with Company policies at all times.

In particular, the Code and Policy cover conflicts of interest, gifts, confidentiality, behaviour and proper use

of assets and information. Pacific Edge’s policy is that donations are not made to any political parties.

Employees are encouraged to report any breaches. Pacific Edge has a Speak Up Policy that is designed

to ensure its employees and contractors are aware and encouraged to raise concerns regarding actual or

suspected wrong doing with regards to ethical, clinical, professional and legal standards in a safe, supported

and protected environment. Alongside the Speak Up Policy, Pacific Edge has a Protected Disclosures Policy

that is designed to promote the public interest by facilitating the disclosure and investigation of matters of

serious wrongdoing whilst protecting complainants who make disclosures of serious wrongdoing in good

faith in an organisation from victimisation or reprisals.

Processes have been established to ensure all employees are aware of and understand these Policies.

SHARE TRADING POLICY

Pacific Edge’s Board and management are committed to ensuring compliance with all regulatory and

market requirements. Pacific Edge’s Share Trading Policy, which applies to all employees and Directors but

has additional trading restrictions applying to Directors and Senior Managers is a core component of this

commitment.

FY 2025 GOVERNANCE STATEMENT

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

47

PRINCIPLE 2: BOARD COMPOSITION & PERFORMANCE
“To ensure an effective Board, there should be a balance of independence, skills, knowledge, experience

and perspectives.”

Pacific Edge’s Board operates under a written Board of Directors’ Charter (Charter) which sets out the

roles and responsibilities of the Board (and clearly distinguishes and discloses the respective roles and

responsibilities of the Board and management). The focus of the Board is the creation of company and

shareholder value and ensuring the Company is committed to best practice. The charter is available on the

Pacific Edge website.

Responsibility for the day-to-day management of Pacific Edge has been delegated to the Chief Executive

Officer (CEO) and other Senior Management. Management is responsible for implementing the objectives

and strategies approved by the Board, through a set of delegated authorities.

The primary responsibilities of the Board include:

• overall governance and providing strategic leadership;

• ensuring compliance with the Company’s constitution;

• setting clear goals for the Company, ensuring that there are appropriate strategies in place for achieving

those goals;

• monitoring the Company’s performance against its approved strategic, business and financial plans;

• appointment of the Chair and CEO;

• ensuring that the Company follows high standards of ethical and corporate behaviour;

• ensuring that the Company has appropriate risk management policies in place; and

• appointing the Company auditors and setting the annual auditors fees.

As at 1 April 2025, the Board was comprised of six non-executive independent Directors. During the year

ended 31 March 2025, independent Director Mark Green retired from the Board, effective 24 September

2024.

The Chairman is an independent Director who is elected by the Directors. The Chairman and the CEO roles

are not executed by the same individual.

Directors are selected based on the diversity of skills needed as defined by the Company’s skills matrix

taking into account the composition of the Board in relation to the Company’s needs and operating

environment. The Board considers that its members currently have the appropriate balance of

independence, skills, knowledge, experience and perspectives necessary to lead Pacific Edge.

Board Skils Matrix

Posible focus of new

Board appointments

Medicine/Diagnostics

Financial Acumen

Sales/Marketing/Distribution

Legal/Regulatory/Risk

Corporate Governance

New Market Development

Capital and Financial Markets

Health, Safety, Environment and Sustainability

■ High Capability ■ Moderate Capability

48

It is acknowledged that current Director Anatole Masfen has been a Board member for approximately
17 years. While this tenure is beyond the 12-year period listed as a factor that may cause questions on

independence, the Board value the extensive knowledge and history available to the Board and are satisfied

that Anatole continues to bring independent judgment to bear on issues before the Board and acts in the

best interests of the issuer and represents the interests of its financial product holders generally.

The profile of each Director including their experience is covered on pages 42-43 of this report. Statements

on Director Independence and their ownership interests are covered in the Statutory Information section on

pages 109 to 113 of this report. Director attendance at Board meetings is covered on page 51 of this report.

Director Profiles are also available on the Company’s website.

NOMINATION AND APPOINTMENT OF DIRECTORS

The procedure for the nomination and appointment of Directors to the Board is set out in the Charter.

While the nomination process for new Director appointments is the responsibility of the Board as a whole,

the Nomination Committee is responsible for identifying, reviewing and recommending candidates to the

full Board. The Board may engage consultants to assist in the identification, recruitment and appointment

of suitable candidates. The Company undertakes proper checks before appointing a Director and putting

forward a candidate for election as a Director. Key information is provided to shareholders when a Director

stands for election or re-election.

Directors will retire and may stand for re-election by shareholders at least every three years, in accordance

with the NZX Listing Rules. A Director appointed since the previous annual meeting holds office only until

the next annual meeting but is eligible for re-election at that meeting.

The Board asks for Director nominations each year prior to the Annual Shareholders Meeting, in accordance

with the constitution of the Company and the NZX Listing Rules.

INDUCTION AND PROFESSIONAL DEVELOPMENT

Newly elected Directors undergo a formal induction programme to ensure they have working knowledge of

our business. This includes one-on-one meetings with management and a tour of the laboratory and R&D

facilities. They are expected to familiarise themselves with their obligations under the constitution, Board

Charter and the NZX Listing Rules. Training is also provided to new and existing Directors where required to

enable Directors to understand their obligations.

The Company encourages all Directors to undertake appropriate training and education so that they

may best perform their duties. This includes attending presentations on changes in governance, legal

and regulatory frameworks; attending technical and professional development courses; and attending

presentations from industry experts and key advisers. Additional industry related training is provided by

Pacific Edge on a regular basis.

BOARD PERFORMANCE

The performance of the Board is reviewed periodically to assess the performance of each Director, each

Committee and the Board as a whole. The most recent external evaluation of Board performance was

undertaken in September 2022. The Chair of the Board also regularly engages with individual Directors to

evaluate and discuss performance and professional development.

DIVERSITY

Pacific Edge is committed to bringing diversity to life in its employment practices and across all aspects of

the business.

The Board and Company believe in creating a flexible workplace that values difference and enhances

business outcomes. We follow equal employment practices, ensuring that our recruitment and selection,

development and talent management approaches enable inclusion and diversity at all levels.

The Diversity Policy outlines Pacific Edge’s approach towards diversity. While no measurable targets

have been set for diversity, the Remuneration Committee provides oversight of employment practices

and HR processes and practices and the Board is comfortable that these are in line with the intent of the

Diversity Policy.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

49

Pacific Edge’s workforce demonstrates balance between genders across the business, but a skew to males is
evident in the leadership teams and on the Board. We explore opportunities to increase diversity at all levels

of the workforce.

Pacific Edge will always hire the best person for the job based on capability, acceptance and best fit for the

business. We actively seek out those with a variety of thinking styles, backgrounds, and abilities. Where two

candidates applying for a role possess equivalent capability, competence and fit, then diversity becomes

the final criteria for appointment. We actively monitor for bias in both our recruitment process and our

remuneration practices.

The Officers of the Company (as defined by the NZX Listing Rules) are the CEO and specific direct reports

of the CEO having key functional responsibility. As at 31 March 2025, females represented 21% of Directors

and Officers of the Company (FY24: 13%).

The diversity of our workforce is detailed in our ESG section on page 31 of this report.

PRINCIPLE 3: BOARD COMMITTEES

“The Board should use Committees where this will enhance its effectiveness in key areas, while still

retaining Board responsibility.”

The Board has delegated a number of its responsibilities to Committees to assist in the execution of the

Board’s responsibilities. These Committees review and analyse policies and strategies which are within their

terms of reference.

Committee members are appointed from members of the Board with membership reviewed on an annual

basis. Committees examine proposals and, where appropriate, make recommendations to the full Board.

Committees do not take action or make decisions on behalf of the Board unless specifically mandated by

prior Board authority to do so.

Management may only attend committee meetings at the invitation of the Committee.

The current Committees of the Board are the Audit & Risk Committee, People and Culture Committee,

Nominations Committee and Capital and M&A Committee.

The Committees have terms of reference (Charters), which are reviewed and approved by the Board. All

charters are reviewed approximately every two years. These are available on the Company’s website.

Committee Membership as at 31 March 2025

Audit & Risk

Committee

People and Culture

Committee

Nomination

Committee

Capital and M&A

Committee

Tony Barclay (Chair)

Sarah Park

Chris Gallaher

Anna Stove (Chair)

Bryan Williams

Anatole Masfen

To n y Barclay

Chris Gallaher (Chair)

Bryan Williams

Anna Stove

Anatole Masfen

Chris Gallaher

Sarah Park

Peter Meintjes

To n y Barclay

50

DIRECTOR MEETING ATTENDANCE
The Board meets as often as it deems appropriate including sessions to consider the strategic direction of

Pacific Edge and forward-looking business plans. Video and/or phone conferences are also used as required.

The table below sets out Director attendance at Board and Committee meetings during FY 25.

Board

Audit & Risk

Committee

Nomination

Committee

People and

Culture

Committee

Capital

and M&A

Committee

Tony Barclay

13/136/61*1/1

2/2

Chris Gallaher

13/136/61/1-

2/2

Anatole Masfen

13/131*1/1

2/2

Sarah Park

12/136/6--

2/2

Anna Stove

12/131/1

1/1

-

Bryan Williams

12/13

1*

1/1

0/1

-

Mark Green (resigned Sept 24)

5/53/3--

-

*Indicates optional attendance

AUDIT & RISK COMMITTEE

Pacific Edge’s Audit & Risk Committee is comprised solely of Directors of the Company, with all members

being independent Directors. As at 31 March 2025, there were three members of the Audit & Risk Committee

with all having an accounting or financial background. The Chair of the Audit and Risk Committee is not the

Chair of the Board.

As per the Board Charter, the responsibilities of the Audit & Risk Committee include providing oversight

in four distinct areas (financial reporting, audit functions, risk management and sustainability and climate

related disclosures) and include as a minimum:

Financial Reporting

• reviewing the financial reports and advising all Directors whether they comply with the appropriate

laws and regulations;

• ensuring that the processes are in place and monitoring of those processes so that the Board is

properly and regularly informed and updated on corporate financial matters;

• reviewing the Company’s tax position, compliance and any exposures; and

• recommending to the Board for adoption significant changes in accounting policies and annual and

six-monthly financial statements.

Audit Functions

• ensuring that the external auditor or lead audit partner is changed at least every five years;

• monitoring and reviewing the independent and internal auditing practices;

• having direct communication with and unrestricted access to the independent auditors and any

internal auditors or accountants; and

• recommending annually to the Board the appointment of the independent auditor.

Risk Management

• ensuring that management has established a risk management framework which includes policies

and procedures to effectively identify, treat, monitor and report key business risks;

• review key insurance policy terms and cover adequacy and make recommendations to the Board for

adoption of the insurance cover;

• overseeing compliance of the Company’s Treasury activities including periodic review of performance

against the Policy; and

• ensuring Treasury issues raised by auditors (both internal and external) are resolved and/or a plan to

resolve is agreed immediately.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

51

Sustainability and Climate Related Disclosures
• reporting to the Board on the delivery of the Sustainability Policy and progress with adoption and

compliance with the Aotearoa New Zealand Climate Standards (Climate Reporting Standards) published

by the XRB; and

• noting the disclosure requirements of the Climate Reporting Standards, the Committee will report to the

Board on the Physical and Transitional Climate related risks and opportunities facing the Company.

Directors who are not members of the Committee are able to attend Audit & Risk Committee meetings as

they wish. Employees may only attend those meetings at the invitation of the Audit & Risk Committee.

NOMINATION COMMITTEE

The Board has established a Nomination Committee to recommend Director appointments to the Board.

The Nomination committee operates under a written Charter. All members of the Nomination Committee are

independent Directors.

PEOPLE AND CULTURE COMMITTEE

The Board has a People and Culture Committee to recommend the remuneration for Directors to the

shareholders and to oversee the remuneration of the Officers/senior managers of the Company. The People

and Culture Committee operates under a written Charter. All members of the People and Culture Committee

are independent Directors. The CEO does not participate in any discussions concerning the

CEO’s remuneration.

The People and Culture Committee is responsible for ensuring that the Company has a sound Remuneration

Policy to attract and retain high performing individuals. The Remuneration Policy is available on the

Company’s website.

Directors’ remuneration is also considered by the People and Culture Committee, within the limits that have

been approved by the shareholders of the Company.

The Committee makes recommendations to the Board on remuneration packages for the CEO. Any

recommendations to shareholders regarding Director remuneration are provided for approval in a

transparent manner.

OTHER COMMITTEES

The Board establishes other Committees as required. In the case of a Control Transaction

1

, Pacific Edge will

form an Independent Control Transaction Committee to oversee disclosure and response and engage expert

legal and financial advisors to provide advice on procedure. The Board has established appropriate processes

and protocols that set out the procedures to be followed in the event of a Control Transaction for the

Company.

PRINCIPLE 4: REPORTING & DISCLOSURE

“The Board should demand integrity in financial and non-financial reporting, and in the timeliness and

balance of corporate disclosures.”

CONTINUOUS DISCLOSURE

The Board focuses on providing accurate, adequate and timely information both to its shareholders and

to the market generally. This enables all investors to make informed decisions about the Company. All

significant announcements made to NZX and ASX, and reports issued, are posted on the Company’s

website.

The Company has procedures in place to ensure that it complies with its continuous disclosure requirements

under the NZX and ASX Listing Rules. The Continuous Disclosure Policy governs the release to the market of

all material information that may affect the value of the Company.

1

A control transaction is defined in the NZX Corporate Governance Code as any transaction which: (i) is regulated by the Takeovers Code;

(ii) would be regulated by the Takeovers Code if it were not structured as a scheme of arrangement under Part 15 of the Companies Act 1993;

or (iii) is a Restricted Transfer under Appendix 3 of the Rules.

52

COMPANY POLICIES
Copies of the key governance documents, including the Continuous Disclosure Policy, Ethical Behaviour

Policy, Share Trading Policy, Board and Committee Charters and Diversity Policy are available on the

governance section of Pacific Edge's website.

FINANCIAL REPORTING

Pacific Edge’s management team is responsible for implementing and maintaining appropriate accounting

and financial reporting principles, policies, and internal controls. These are designed to ensure compliance

with accounting standards and applicable laws and regulations.

The Audit & Risk Committee oversees the quality and integrity of external financial reporting, including the

accuracy, completeness, balance and timeliness of financial statements. It reviews Pacific Edge’s full and

half year financial statements and makes recommendations to the Board concerning accounting policies,

areas of judgement, compliance with accounting standards, stock exchange and legal requirements, and the

results of the external audit.

All matters required to be addressed, and for which the Committee has responsibility, were addressed

during the reporting period.

The CEO and CFO have confirmed in writing to the Board that Pacific Edge’s external financial reports

present a true and fair view in all material aspects. Pacific Edge’s full and half year financial statements are

available on the Company’s website.

The Chief Financial Officer holds the role of Company Secretary. In all accounting and secretarial matters,

the Board ensures that the Secretary’s reports are objective and that the Secretary has unfettered access to

the chair and the audit committee, without reference to the CEO.

NON-FINANCIAL REPORTING

Non-financial information is provided on a regular basis to shareholders to allow them to measure the

progress of the company. Pacific Edge’s Board and management are focused on identifying areas which

are of primary importance to creating a sustainable business, achieving strategic goals and meeting the

expectations of key stakeholders.

Pacific Edge discusses its strategic objectives and its progress against these in the Chair and CEO’s

commentary in shareholder reports and in the sustainability section of this report. Key non-financial metrics

used by Pacific Edge to demonstrate its progress are Laboratory Test Throughput and Commercial Tests

among others.

PRINCIPLE 5: REMUNERATION

“The remuneration of directors and executives should be transparent, fair and reasonable.”

The Company has a People & Culture Policy which outlines the processes and framework for remuneration

of the Chairperson, the Directors, the CEO and management. The People and Culture Committee is

responsible for recommending to the Board the remuneration for the Chair, Directors and the CEO, and

consulting and approval, on the recommendation of the CEO for the appointment and employment terms of

all Executives (other than the CEO).

Shareholders fix the total remuneration available for directors. Approval is sought for any increase in

the pool available to pay Directors’ fees, and any recommendations to shareholders regarding Director

remuneration are provided for approval in a transparent manner.

External advice is sought on a regular basis to ensure remuneration is benchmarked to the market for senior

management positions, Directors and Board positions. A review of Director remuneration was undertaken in

June 2021 and approved at the 2021 Annual Shareholders’ Meeting. An updated review has been completed

in the 2025 year, and a proposal for an increase in the Directors Pool will be presented for consideration at

the 2025 Annual Shareholders’ Meeting.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

53

Further details on remuneration are included in the Remuneration Section of this Annual Report, including
the remuneration arrangements in place for the CEO, on pages 63 to 68.

While there is no formal requirement, the majority of Pacific Edge’s Directors own shares in the Company

either directly or through related entities. There is a provision for the Company to make a retirement

payment to a Director if approved by shareholders; however, no retirement payments were made in FY 25.

PRINCIPLE 6: RISK MANAGEMENT

“Directors should have a sound understanding of the material risks faced by the issuer and how to manage

them. The Board should regularly verify that the issuer has appropriate processes that identify and manage

potential and material risks.”

The Board is responsible for ensuring that appropriate policies and procedures are in place to identify and

manage the key risks of the Company, and these risks are managed through the Audit & Risk Committee.

The Audit & Risk Committee operates in line with its Charter, which sets out its responsibilities for

identifying, monitoring, treating and reporting on key business risks.

The executive team and senior management are required to regularly identify the major risks affecting the

business, record them in the risk register and develop structures, practices and processes to manage and

monitor these risks. Pacific Edge has a strong risk culture, with risk management embedded in everyday

practices. The comprehensive risk management framework uses Failure Modes and Effect Analysis (FMEA)

to manage risk.

A comprehensive review of the risk register was completed in February 2025, and incorporates risk

mitigation strategies, processes and policies. Management continues to monitor individual risks, as does

the Board. The risk register now incorporates climate related risks and opportunities. Risks are discussed at

scheduled Board meetings, with a focus on any changes and emerging risks and opportunities.

Pacific Edge maintains insurance policies that it considers adequate to meet its insurable risks.

The Board is satisfied that Pacific Edge has in place a risk management framework to effectively identify,

manage and monitor Pacific Edge’s principal risks, to the extent practicable.

Pacific Edge’s material risks and how these are being managed are outlined and discussed in the Risk

Analysis on pages 57 to 62.

HEALTH AND SAFETY

The Company takes responsibility, so far as is reasonably practicable, at all its sites to protect the health,

safety and welfare of all staff and people on Company sites, and acts in compliance with all of its legal and

ethical obligations.

Pacific Edge aims to proactively identify and manage all identified hazards across the company. The

Company’s health and safety performance is monitored and reviewed regularly by management, and the

Board. The Company’s goal is to maintain a safe and effective operating environment and takes its duty of

care to staff, contractors and visitors very seriously.

Lag Indicators: There were no serious harm incidents reported during FY 25 and no days lost to workplace

incidents at any Company site. There were 11 near misses over the group in FY 25.

Lead Indicators: There were seven dedicated health and safety training sessions completed during FY 25 as

well as four safety audits conducted. In addition, there are 28 ‘Toolbox Talk’ presentations available for teams

to continue their health and safety journey. Risk assessments were also conducted in the New Zealand and

US Laboratories.

54

PRINCIPLE 7: AUDITORS
“The Board should ensure the quality and independence of the external audit process.”

EXTERNAL AUDITORS

The Board’s relationship with its external auditors is governed by the Audit & Risk Committee Charter.

The Charter sets out the Audit & Risk Committee’s responsibilities in relation to corporate accounting

and reporting practices of the Company, along with the quality and integrity of financial reports and the

Company’s climate report. It is the responsibility of the Audit & Risk Committee to maintain free and open

communication between the Directors and external auditors and to approve any non-audit engagements

performed by the audit firm.

For FY 25, PricewaterhouseCoopers (PwC) was the external auditor for the financial accounts of Pacific

Edge Limited. PwC was re-appointed under the Companies Act 1993 at the 2024 Annual Shareholders

Meeting. The last audit partner rotation was in FY 21 with another rotation due in FY 26.

PwC also completed the limited assurance report on Pacific Edge Limited’s Greenhouse Gas (GHG)

Disclosures (Scope 1 and 2) within the climate report for the 12 months ended 31 March 2025.

All audit work at Pacific Edge is separated from non-audit services, to ensure that appropriate independence

is maintained. The Audit and Risk Committee review and approve the nature and scope of other professional

services (if any) provided to the Company by the external auditor and consider the relationship to the

auditor’s independence. The amount of fees paid to PwC during FY 25 are identified on page 82.

PwC has provided the Audit & Risk Committee with written confirmation that, in their view, it was able to

operate independently during the year.

PwC attends each Annual Meeting of the Company, and the lead audit partner is available to answer

questions from shareholders at that Meeting. PwC attended the 2024 Annual Meeting.

INTERNAL AUDITS

Internal audits are used as a Quality Management tool for the systematic and independent examination of

Pacific Edge’s operational processes as they relate to product and service provision.

Pacific Edge has conducted internal audits of its manufacturing, clinical diagnostic laboratories, R&D, Supply

Chain Operations, Digital and Quality Operations at planned intervals to verify that its Quality Management

System is effectively implemented and maintained and provides continuous improvement opportunities

in system processes. In addition, audits by external Notified Bodies and government regulators took place

to ensure compliance with the requirements of multiple International Standards, such as ISO9001:2015,

ISO13485:2016 and ISO15189:2012.

The latest external audits in New Zealand took place in December 2024 (Telarc, ISO9001/ISO13485),

February 2024 (CLIA) and in May 2024 (IANZ, ISO15189). All were completed satisfactorily. In PEDUSA, the

laboratories were audited by New York State in September 2023 and by CAP in October 2023. Both audits

were completed successfully and the next audits are due in the current calendar year.

PRINCIPLE 8: SHAREHOLDER RIGHTS & RELATIONS

“The Board should respect the rights of shareholders and foster constructive relationships with

shareholders that encourage them to engage with the issuer.”

SHAREHOLDER COMMUNICATIONS

Pacific Edge is committed to ensuring that its shareholders are kept up to date with key activities and are

provided with relevant information about the Company and its performance.

The Company communicates with shareholders during the financial year through quarterly investor updates,

shareholder letters, annual and half year reports and at the Annual Shareholders Meeting (ASM). All written

communications and reports are available on the Company’s website, as well as emailed to shareholders

who elect to be emailed.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

55

In addition to shareholders, Pacific Edge has a wide range of stakeholders and maintains open channels
of communication for all audiences, including brokers, the investing community and the New Zealand

Shareholders’ Association, as well as its staff, suppliers and customers.

SHAREHOLDER MEETINGS

In accordance with the NZX Listing Rules, shareholders have the right to vote on major decisions which

may change the nature of the Company. Each shareholder has one vote per share and voting is conducted

by polls.

The Notice of the Annual Meeting is generally announced on the NZX, sent to shareholders and posted on

to the Company’s website at least 20 working days prior to the Meeting each year. However, due to the

complexities of the ongoing capital raising the Company does not expect to achieve this goal for the 2025

Annual Shareholders’ Meeting, but will deliver the report ahead of the 10 business days required under the

Companies Act 1993.

DIRECTORS’ REMUNERATION

Remuneration of Directors and senior executives is the key responsibility of the People and Culture

Committee. Pacific Edge’s policy is to offer competitive Director fees to attract and retain high quality,

appropriately skilled Directors, who will best add value to the Company.

56

RISK ANALYSIS
AND MANAGEMENT

57

As a growth company, there are a number of risks which could impact Pacific Edge. We believe it is
important for our shareholders to have an understanding of these risks and the processes the Board and

management have put in place to mitigate these risks.

As a health provider, we must meet stringent regulatory, quality, health and safety and manufacturing

standards in a number of countries. Risk management is therefore embedded in everyday practices, which

include regular internal and external audits, training, quality management systems, risk reporting and

promotion of a strong risk culture. Pacific Edge has a comprehensive risk management framework, using

Failure Modes and Effect Analysis (FMEA) as the tool of choice to assess and manage risk.

The Board provides oversight of the senior leadership’s management of key risks. Every departmental leader

is expected to report on risks to the CEO/CFO/COO in every Board meeting cycle with an assessment of

those risks incorporated into the risk register provided to the Board. The Audit & Risk Committee reports to,

and assists, the Board by identifying and reviewing the key risks, assessing their materiality, and ensuring the

risk management processes are adequate. It also helps to ensure the Board has reliable information and that

future events that may create uncertainty or pose a risk are identified and considered.


RiskDetailMitigation

Medicare coverage

uncertainty

Pacific Edge does not currently have

Medicare coverage for its Cxbladder

products.

Medicare previously accounted for the

majority of its US test volumes and,

therefore, a significant percentage of Pacific

Edge's revenue. Although Pacific Edge is

confident that it will regain coverage for

Triage as a result of recent AUA guideline

inclusion and new clinical evidence, there are

no guarantees as to the timing or outcome of

the re-coverage process. Regaining Medicare

coverage could be delayed or not achieved at

all. If Medicare re-coverage was not achieved

or was significantly delayed, it would have

a material adverse impact on Pacific Edge's

financial performance and growth and could

result in the company using up all available

cash before it is able to become profitable

from its ongoing operations.

If the current reconsideration request is

unsuccessful, Pacific Edge will likely need to

complete further clinical studies to provide

new published evidence when submitting

another reconsideration request. That

clinical study will take a number of years

to undertake. Accordingly, if the current

reconsideration request is unsuccessful,

Pacific Edge will need to undertake a

significant restructure of its business to

substantially reduce costs and, potentially,

seek to raise further capital.

• Mitigation of market disruption risk can

come by seeking to operate in multiple

geographies with multiple payers and

marketing multiple products. For each

of those products, we mitigate this risk

by continued commitment to increasing

clinical evidence generation to support

ongoing coverage and increasingly strong

language in medical policy and guidelines.

Furthermore, we mitigate risk by seeking

medical policy for reimbursement from

new healthcare providers and the adoption

of alternate payment methods (such

as patient pay or client billing) for tests

performed. As we introduce additional

products in new areas, we will continue to

reduce our exposure to any potential payer,

geographic or product market disruption.

These mitigations are not expected to fully

offset any reduction in revenue from the

loss of Medicare revenue in the short term,

but are an important growth avenue for

Pacific Edge in the long term.

Pacific Edge is operating at a 'cash burn',

which means that the company spends more

cash that it generates.

On 29 May 2025, Pacific Edge announced an

offer to raise $20 million, consisting of:

• a placement of $15 million of new fully

paid ordinary shares at an issue price of

$0.10 per share, to be offered to selected

investors (the Placement)

• Pacific Edge is pursuing a capital

raise of $20 million to extend the cash

runway to support operations for over 12

months without Medicare coverage and

reimbursement.

• The AUA guideline inclusion as detailed in

this annual report provides Pacific Edge

with several options to build momentum

despite the loss of Medicare coverage.

RISK ANALYSIS AND MANAGEMENT

58

RiskDetailMitigation
Ongoing Financial

Viability cont.

• an offer of $5 million of new fully paid

ordinary shares at an issue price of $0.10

per share to retail investors, by way of a

share purchase plan (the SPP).

• Pacific Edge stated that it may accept

oversubscriptions in both the Placement

and the SPP at its sole discretion.

• The Company completed the Placement on

30 May 2025, raising approximately $16.1

million from the placement of 160,728,498

new fully paid ordinary shares.

• The amount raised was approximately $1.1

million more than the Company sought

after the board of directors resolved to

accept oversubscriptions.

• Shareholder approval is required to

complete the Placement as the Placement

exceeds Pacific Edge's placement capacity

(15% of Pacific Edge's current shares on

issue) and due to the presence of related

party participation in the Placement.

• If the capital raise is undersubscribed,

is not approved by shareholders, or if

Medicare coverage is not achieved or

significantly delayed, or the business is

impacted adversely by other events, there

is a risk to the ongoing financial viability of

Pacific Edge, which may result in investors

losing some or all of their investment.

• Pacific Edge is seeking to regain Medicare

coverage with multiple reconsideration

requests to Novitas to re-open L39365

based on new clinical evidence and an

appeals strategy through the Medicare

Appeals Process and following “External

Review” with the commercial payers in

locations where this is allowed to reverse

claim denials.

• A draft price for Triage Plus has been

issued by Medicare that is 34% higher than

the current price for existing products.

This higher price lowers the threshold

number of tests for an Account Executive

to achieve profitability, enables faster

scaling and a clearer path to long-term

profitability.

Regulatory,

industry body and

guideline risks

Pacific Edge’s Cxbladder products and

laboratories are regulated and certified by

various government and industry entities

in territories and markets in which the tests

are performed and/or sold. Reimbursement

for these tests may be influenced by

reimbursement rulings from private and/

or government payers. Guidelines issued by

various industry bodies also influence the

treatment and management regimes for

patients, with the potential to impact on the

uptake and use of Cxbladder. If Pacific Edge

is unable to retain or, in certain markets,

gain inclusion in guidelines, or the current

regulatory approvals and reimbursement

obtained for existing products are

removed or reduced, such matters could

have an adverse impact on Pacific Edge’s

financial performance and its ability to

achieve its business plans. If Pacific Edge

is unable to obtain the approvals required

for new products in new territories, or is

unable to obtain future reimbursement

for new products, this could also have an

adverse impact on Pacific Edge’s financial

performance and its ability to achieve its

business plans.

• Pacific Edge’s quality management system

is evolving towards the superset of its

regulatory requirements that includes

ISO-13485, IVDR and FDA.

• To maintain compliance with those

standards, internal audits and external

audits are routinely performed to

ensure compliance in operations and

development.

• The PEDNZ lab operates under ISO:15189,

IANZ and CLIA. The PEDUSA lab operates

under CAP, CLIA and NYS. We have

SOPs developed with expert consultants

that adhere to the highest standard and

regularly perform internal audits.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

59

RiskDetailMitigation
CompetitionThe global cancer diagnostics industry is

highly competitive, with research undertaken

by a large number of commercial and not for

profit institutions globally on new diagnostic

tools. There are also a large number of

well capitalised diagnostics competitors

operating in the industry. There is a risk that

Pacific Edge’s competitors may discover,

develop or commercialise products more

successfully than Pacific Edge, which could

render Pacific Edge’s products obsolete or

otherwise uncompetitive, resulting in adverse

effects on Pacific Edge’s revenue, margins

and profitability.

• Cxbladder Triage is included in the

AUA microhematuria guideline, the only

biomarker with Grade A

1

evidence.

• We have yet to observe any competing

bladder cancer diagnostic product that has

developed clinical evidence in a robust AV,

CV, CU framework required for coverage

and guidelines inclusion.

• Matching or improving upon the existing

AV, CV, CU and real world evidence for

Cxbladder would take substantial time and

money and is the most significant barrier

to entry.

• We continue to invest in Research and

Development for Cxbladder products,

to improve test performance and value

for clinical decision making, including

development of a kit-based IVD to

accelerate momentum in new markets.

Product and

technology risk

Pacific Edge relies on the performance

and reliability of its Cxbladder suite of

products, laboratory operations and IT and

technical systems. While the performance of

Cxbladder has been demonstrated in various

scientific journal publications, any change to

the reliability, repeatability, reproducibility

or accuracy of Cxbladder products and

technology systems has the potential

to impact Pacific Edge’s business and

reputation. Cyber attacks on Pacific Edge’s

digital systems and platforms also have

the potential to impact the delivery of test

results. Financial, reputational and litigation

consequences relating to underperformance

and unreliability, or the inability to deliver,

test results (including due to adverse

cyber incidents) have the potential to be

significant and could be materially adverse

to the company's financial performance and

position.

• Completed clinical studies have validated

our test performance.

• Clinical studies in progress targeted to

provide additional clinical utility data

supporting wider adoption by the medical

community and wider reimbursement by

funders and third party payers.

• Modern digital practices have been

introduced to deliver a secure digital

infrastructure.

• Expansion into new geographies and the

introduction of a kit-based IVD can reduce

single market risks.

General economic

conditions

Pacific Edge’s operating and financial

performance is influenced by a variety of

general economic and business conditions in

New Zealand, the United States, Southeast

Asia and globally. A prolonged deterioration

in general economic conditions, which may

lead to a decrease or reprioritisation of

healthcare spending, has the potential to

have a material adverse effect on Pacific

Edge’s business or financial condition (or

both).

• Expansion into new geographies

can mitigate the risk of an economic

deterioration in a single market.

1

The AUA defines ‘Grade A’ evidence as evidence with a high certainty rating and notes evidence of this grade makes it "very confident that the true effect

lies close to that of the estimate of the effect

60

RiskDetailMitigation
LitigationIn the ordinary course of conducting its

business, Pacific Edge is exposed to potential

litigation and other proceedings, including

through claims of intellectual property

infringement or breach of agreements. If

such proceedings are brought against Pacific

Edge, Pacific Edge could incur considerable

defence costs (even if successful), with the

potential for damages and costs awards

against Pacific Edge if it were unsuccessful,

which could have a significant adverse

financial impact on Pacific Edge.

Circumstances may also arise in which

Pacific Edge considers that it is reasonable

or necessary to initiate litigation or other

proceedings, including for example to

protect its intellectual property rights.

• We have an intellectual property portfolio,

supplemented by trade secrets.

• We have developed a network of specialist

legal representation in the US.

• We have strong quality systems embedded

throughout the business.

Key Person RiskThe success of our business depends

significantly on the continued contributions

of our executive team, scientific leaders,

and key technical staff. The unexpected

departure of any of these individuals could

disrupt operations, delay research and

development efforts, and negatively impact

strategic initiatives. Attracting and retaining

top talent in a competitive biotech labor

market remains a critical challenge.

• We have cross training for key roles and

Employment Agreements for Senior

Leaders generally include 3 month notice

periods.

• PEB has developed remuneration policies

that position it well to retain key staff in NZ

and USA.

• Focus on retaining key staff to provide the

best opportunity to regaining Medicare

coverage in the United States supported

by retention agreements.

• Key person insurance for CEO in place.

Market volatility

of Pacific Edge’s

shares

Any investment in equity capital markets

carries general risks. Pacific Edge’s shares are

currently listed on NZX and the ASX, and are

subject to the usual market-related forces

which impact on Pacific Edge’s share price.

There can be no assurance that trading in

the shares following the ongoing share offer

will not result in the share price trading at

levels below the price paid by investors in

the offer. The equity markets can be subject

to pronounced volatility. This volatility could

have a materially adverse impact on the

market price of Pacific Edge shares.

Factors such as the risk factors disclosed in

this Annual Report as well as other factors

could cause the market price of Pacific

Edge’s shares to decline or to materially

fluctuate. It also is possible that new market

risks may develop as a result of the New

Zealand or Australian markets experiencing

extreme stress, or due to existing risks

manifesting themselves in ways that are not

currently foreseeable.

A weakening in the New Zealand or

Australian dollar as against other currencies

will cause the value of the shares to decline

in any portfolio which is denominated in a

currency other than New Zealand dollars.

• We are aware of the risks associated with

our shares, such as low levels of liquidity,

a number of large investors, high volatility

in our share price and external influences

from investor confidence. The dual listing

on the ASX in September 2021 provided

some mitigation to this risk.

• A comprehensive Treasury Policy is in

place to manage liquidity risk, FX risk,

counterparty credit risk, cash management

and interest rate risk. The Treasury Policy is

reviewed at regular meetings of the board

and compliance with policy is monitored

by the Audit and Risk committee.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

61

RiskDetailMitigation
New product

development

Pacific Edge continues to leverage its suite of

patents and intellectual property to explore

new products and applications. There is a risk

that those development efforts may not be

successful or may take longer and be more

expensive than anticipated, and as a result

Pacific Edge’s investment will be delayed or

lost. This risk could arise due to a number of

factors, including delays in commencement

or completion of scientific studies. Any failure

or significant delay in the development of

one or more of Pacific Edge’s new products

and product extensions may have a material

negative impact on Pacific Edge’s financial

performance and growth.

• Development of new products is supported

by the Scientific Advisory Board, an

internationally renowned team of scientific

advisors. Their skills, experience and

capability cover a range of disciplines from

clinical medicine and pathology through to

biotechnology R&D and commercialization.

• Internal controls with regular management

and board checkpoints to mitigate the risk

of developments failing to deliver on their

objectives..

62

REMUNERATION
63

The Pacific Edge Limited People and Culture Committee operates as a sub-committee under the guidance
of the Board of Directors, to ensure the Total Rewards framework that is in place is appropriate to attract,

retain and reward current and future employees of the Pacific Edge Group. The People and Culture

Committee ensures that individual employee performance is aligned to the strategy and performance of the

Company along with the interests of the shareholders.

The current total Directors’ fee pool for non-executive Directors of Pacific Edge Limited, approved by the

shareholders at the Annual Shareholders Meeting on 29 July 2021 was $465,000

1

per annum and was based

on six Directors. With the addition of Tony Barclay on 21 March 2022, the number of Directors increased to

seven.

In accordance with NZX Listing Rule 2.11.3 which permits an issuer to increase the aggregate amount

payable to the Directors to take into account an additional Director without shareholder approval, the pool

for non-executive Directors of Pacific Edge increased to $529,000. With the retirement of Mark Green on 24

September 2024, the number of Directors reduced back to six, with the Directors’ fee pool reducing back to

$465,000 per annum.

The total amount of fees paid to Directors for the year ended 31 March 2025 (FY 25) was $470,000.

PositionNumber

FY 25

Fee per

Director

FY25

Total

Directors

Fees Paid

FY 25

Number

FY 24

Fee per

Director

FY 24

Total

Directors

Fees Paid

FY 24

Chair1

$115,000$115,000

1

$115,000$115,000

Deputy Chair1

$70,000$70,000

1

$70,000$70,000

Non-executive

Directors

5 to Sept 24

4 from Oct 24

$60,000$270,000

5

$60,000$300,000

Chair Audit & Risk

Committee

1

$10,000$10,000

1

$10,000$10,000

Special Governance

Allocation

$5,000$5,000$5,000$5,000

Total Fee Pool

$470,000$500,000

Any proposed increases in non-executive Director fees and remuneration is put to shareholders for approval

at the Annual Shareholders’ Meeting by way of ordinary resolution. If independent advice is sought by the

Board, it is disclosed to shareholders as part of the approval process.

Directors also receive reimbursement for reasonable travelling, accommodation and other expenses incurred

in the course of performing their duties. Other than as Chair of the Audit and Risk Committee, and any

potential fees received from the Special Governance Allocation, Directors do not receive any additional

fees for positions on Committees of the Board or subsidiary companies. Directors’ fees exclude GST, where

applicable.

REMUNERATION

1

All references are to New Zealand dollars unless otherwise stated.

64

Non-executive Directors received the following Directors’ fees from the Company in the year ended
31 March 2025:

DIRECTORS’ FEES

FY 25

($000)

FY 24

($000)

Pacific Edge Limited Board

C. Gallaher (Chair)$115.0$115.0

B. Williams (Deputy Chair)$70.0$70.0

S. Park^ $67.5$70.0

A. Masfen$60.0$60.0

A. Stove*$65.0$65.0

M. Green

(retired 24 September 24)$30.0$60.0

T. Barclay^$62.5$60.0

TOTAL$470.0$500.0

^The Chairperson fee for the Audit and Risk Committee was split for the FY 25 year with T. Barclay replacing

S. Park as Chair from January 2025.

*Includes payments made to Director out of the Special Governance Allocation relating to the performance

of duties as chair of the People and Performance Committee that are considered additional to the expected

duties of the Board.

CHIEF EXECUTIVE OFFICER TOTAL REWARD

The review and approval of the Chief Executive Officer Dr Peter Meintjes’ (CEO) Total Reward package is

the responsibility of the Board. The Total Reward package of the CEO for the year ended 31 March 2025 is

detailed below.

Structure

The CEO’s Total Reward package comprises:

• A fixed base salary, including Kiwisaver contributions by the Group.

• An at-risk short-term incentive (STI) payable annually of up to 40% of base salary subject to the Board’s

assessment of both individual and Company performance.

• A retention incentive. During the FY 24 year, the Board identified some employees as key individuals

required to re-architect evidence generation and market access capabilities to regain Medicare coverage

and preserve long-term shareholder value. The individuals, including the CEO, were contracted with

a retention incentive that rewarded staff staying with Pacific Edge for three years while the Company

sought to gain coverage certainty and guideline inclusion. In addition to tenure, the retention incentive

also provides incentives linked to explicit coverage and American Urological Association (AUA)

treatment guideline inclusion. FY 25 is the first year the Retention Incentive has been paid.

• A long-term incentive (LTI) of up to 20% of base salary which includes non-cash share options granted

by the Company that will vest, based on vesting criteria (further detail provided below).

Total CEO Rewards

Fixed Base

Salary

(base salary

inclusive of

employer

Kiwisaver

contribution)

($000)

STI Cash

($000)

Retention

Incentive

($000)

Total cash

($000)

STI Non

Cash

($000)

STI %

Achieved

(100% =

40% of Base

Salary)

Actual Total

Reward

($000)

FY 25$715$184$202$1,101$2477%$1,125

FY 24$703$164-$867$22 73% $889

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

65

Non-cash Total Rewards
During FY 25, the CEO was granted 270,215 ordinary shares as a non-cash consideration in recognition of his

performance as an employee of the Company in lieu of a cash STI and in addition to salary. These shares had

a present value of $24,319 when issued (at $0.09 per share).

Short Term Incentives

Short term incentives (cash and non-cash) paid during the FY 25 year totalled $208,475. This payment

was assessed by the Board as 77% of the maximum STI available after assessing both the Company’s

performance (weighted 70% and includes criteria such as Company financial performance, growth and the

delivery of strategic initiatives) and individual performance (weighted 30% focused on delivery of strategic

initiatives). The maximum STI is up to 40% of base salary as at 31 March 2025.

Retention Incentive

The first of three potential tenure related retention incentives of $202,004 was paid during FY 25. This

payment was 30% of base salary. In addition to tenure, the retention incentive also provides incentives linked

to explicit coverage and AUA treatment guideline inclusion which was not paid during the FY 25 year.

Long Term Incentives

There were 1,171,504 options issued to the CEO on 11 July 2024.

Subject to the continuous employment of the option holder (other than as a result of death or disability),

the options will vest in three equal tranches, being 1 Year after issue, 2 Years after issue and the last tranche

3 Years after issue. Options must be exercised within 4 years of the relevant vesting date, unless the option

holder ceases to be an employee of the Company (or a subsidiary) other than as a result of permanent

retirement, death or disability in which case all options that have vested must be exercised within two

months of the date on which the option holder ceases to be employed.

The third tranche of 600,000 options from the 3,000,000 options issued during FY 22 vested 18th February

2025 with an exercise price of $1.25. The options expire four years after vesting if not exercised.

Table of long term incentives issued to the CEO:

Issue DateNumber of OptionsVest DateExpire DateExercise Price

11 July 2024390,501 11 July 202511 July 2029$0.101

11 July 2024390,501 11 July 202611 July 2030$0.114

11 July 2024390,502 11 July 202711 July 2031$0.128

25 October 20232,534,45525 October 202525 October 2029$0.253

25 October 20232,534,45525 October 202625 October 2030$0.285

25 October 20232,534,45625 October 202725 October 2031$0.320

18 February 2022600,00018 February 202318 February 2027$1.150

18 February 2022600,00018 February 202418 February 2028$1.250

18 February 2022600,00018 February 202518 February 2029$1.250

18 February 2022600,00018 February 202618 February 2030$1.250

18 February 2022600,00018 February 202718 February 2031$1.250

TOTAL11,774,870$0.509

66

EMPLOYEE TOTAL REWARDS
The Company’s salaried employee Total Rewards program consists of:

• Base salary (all employees).

• Variable Incentives:

- Short Term Incentive (STI): Variable component offered only to the CEO and senior leaders and

awarded annually based on the achievement of a combination of individual goals and Company

performance targets.

- Long-Term Incentive (LTI): Equity component offered only to the CEO and senior leaders and

designed as a long-term retention tool using Share Options.

- Sales Incentive: offered only to eligible sales employees and designed to reward achievement of

test volumes and activity delivered against set targets.

• Retention Incentive: With the uncertainty created for Pacific Edge from the loss of Medicare coverage,

in 2023 the Board implemented a retention incentive linked to tenure and successful coverage and

guideline outcomes for Board-identified key employees to reduce the risk of these employees'

leaving employment while the Company seeks coverage certainty and inclusion in the AUA treatment

guidelines. The tenure incentive is scheduled for three years, with payments due if key employees

continue to be employed by Pacific Edge on 1 July 2024, 1 July 2025 and 1 July 2026.

• Benefits such as KiwiSaver in New Zealand or 401k in the USA.

• Non-financial Benefits (e.g. health insurance in the USA, enhanced leave benefits and, enhanced

parental leave benefits).

Base Salary

Salaried employees receive base Total Rewards packages that are benchmarked against similar positions

from companies in comparable industries factoring in size, complexity, responsibilities and local market

context.

Variable Incentives

Short Term Incentives (STI)

The Company operates an STI-based scheme for the CEO and eligible senior leaders. The STI is determined

by achievement against Company and individual goals. Partial achievement of goals will correspond to a

lower payout.

The proportion of total STI that is based on Company and individual goals is related to the Employee

Band, such that higher Bands have a higher proportion of their STI based on Company goals. While STI is

typically paid in cash, an employee may elect to receive up to 50% in equity (shares) unless there are rules

or regulations that limit the Company’s ability to issue shares in a timely manner, in which case 100% of the

STI will be paid in cash.

Long Term Incentives (LTI)

The Company has an LTI Scheme that is designed to attract and retain key talent and capability by offering

Options.

LTI generally vests annually over a three-year period, with 1/3 vesting each year on the first, second and

third anniversary after issue and with a four-year exercise window. If an employee ceases employment within

one year of employment there is no vesting. Unless there are exceptional circumstances, the exercise price

for each tranche of Options is determined by the share price on the date of Board approval. The Company

offers employees the ability to fund their option purchases utilising a cashless exercise within the Options

Agreement.

Sales Incentive

The Company has a sales incentive scheme that is designed to reward eligible sales employees for achieving

test volumes and activity delivered against set targets.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

67

Total Rewards Table
The table below shows the number of employees and former employees of the Group, not being Directors

of the Group, who, in their capacity as employees, received Total Rewards during the period ended 31 March

2025 totalling at least $100,000.

This includes cash and expenditure related to ordinary shares paid in lieu of cash bonuses and excludes the

value of share options that have vested but have not been exercised.

The Group operates in New Zealand, Australia, and the United States where market Total Reward

components differ. Of the employees noted in the table below, 53% are employed by the Group outside New

Zealand. The offshore Total Rewards amounts are converted into New Zealand dollars.

During the year, 72 employees or former employees of the Group, not being Directors of the Company,

received Total Rewards and other benefits that exceeded $100,000 in value as follows:

Total Reward TableFY 25FY 24

$1,120,000 - $1,130,0001

$1,010,000 - $1,020,0001

$960,000 - $970,0001

$880,000 - $900,0001

$790,000 - $800,0001

$750,000 - $760,0001

$700,000 - $710,0001

$640,000 - $650,0001

$600,000 - $610,0001

$550,000 - $560,0001

$540,000 - $550,000

$490,000 - $500,0001

$480,000 - $490,0001 1

$470,000 - $480,0001

$440,000 - $450,00021

$430,000 - $440,0001

$420,000 - $430,00012

$410,000 - $420,0002

$390,000 - $400,0001

$380,000 - $390,0003

$370,000 - $380,00011

$360,000 - $370,00021

$350,000 - $360,00012

$340,000 - $350,00012

$330,000 - $340,00032

Total Reward TableFY 25FY 24

$320,000 - $330,00012

$310,000 - $320,0002 1

$300,000 - $310,00012

$290,000 - $300,0003

$280,000 - $290,00024

$270,000 - $280,00011

$260,000 - $270,00014

$250,000 - $260,00011

$240,000 - $250,000

$230,000 - $240,00024

$220,000 - $230,00021

$210,000 - $220,0004

$200,000 - $210,0003

$190,000 - $200,00032

$180,000 - $190,00015

$170,000 - $180,00023

$160,000 - $170,00035

$150,000 - $160,00041

$140,000 - $150,0003

$130,000 - $140,0003

$120,000 - $130,00052

$110,000 - $120,00089

$100,000 - $110,00077

Total7287

DIRECTORS AND OFFICERS INSURANCE

In accordance with the Companies Act 1993 and the constitution of the Company, Pacific Edge indemnifies

and insures its Directors and Officers, including Directors and Officers of subsidiary companies within the

Group, in respect of liability incurred for any act or omission in their capacity as a Director or Officer of the

Company. This insurance includes defence costs. If an act or omission was to occur that was covered by this

insurance, the Company would pay the liability of the act or omission and be reimbursed by the insurer.

68

CONSOLIDATED
FINANCIAL

STATEMENTS

FOR THE TWELVE MONTHS

ENDED 31 MARCH 2025

69

CONSOLIDATED STATEMENT OF COMPREHENSIVE INCOME
For the twelve months ended 31 March 2025

Note: These Consolidated Financial Statements are to be read in conjunction with the Notes to the Consolidated Financial Statements

Notes

2025

($000)

2024

($000)

REVENUE

Operating Revenue 5 21,846 23,907

Total Operating Revenue 21,846 23,907

Other Income5 903 1,322

Interest Income9 1,925 3,433

Foreign Exchange Gain / (Loss) (58) 631

Total Revenue and Other Income 24,616 29,293

OPERATING EXPENSES

Laboratory Operations 12,490 11,751

Research6 14,631 12,089

Sales and Marketing 17,530 25,590

General and Administration7 9,901 9,398

Total Operating Expenses 54,552 58,828

NET LOSS BEFORE TAX (29,936) (29,535)

Income Tax Expense16--

LOSS FOR THE YEAR AFTER TAX (29,936) (29,535)

Items that may be reclassified to profit or loss:

Translation of Foreign Operations25 142

Disposal of Foreign Operation- (20)

TOTAL COMPREHENSIVE LOSS attributable to

equity holders of the Company

(29,911) (29,413)

Earnings per share for loss attributable to the equity

holders of the Company during the year

Basic and Diluted Earnings per share3 (0.037) (0.036)

70

CONSOLIDATED STATEMENT OF CHANGES IN EQUITY
For the twelve months ended 31 March 2025

Note: These Consolidated Financial Statements are to be read in conjunction with the Notes to the Consolidated Financial Statements

Share

Capital

Accumulated

Losses

Share

Based

Payments

Reserve

Foreign

Currency

Translation

Reserve

Total

Equity

Notes($000)($000)($000)($000)($000)

Balance as at 31 March 2023 294,317 (216,814) 4,418 842 82,763

Loss after tax - (29,535) - - (29,535)

Other Comprehensive Income - - - 122 122

TOTAL COMPREHENSIVE LOSS

attributable to equity holders of the

Company

- (29,535) - 122 (29,413)

Transactions with owners in their

capacity as owners:

Share Based Payments- Employee

Remuneration

8 83 - - - 83

Share Based Payment- Employee

Share Options

8 - - 1,189 - 1,189

Balance as at 31 March 2024 294,400 (246,349) 5,607 964 54,622

Balance as at 31 March 2024 294,400 (246,349) 5,607 964 54,622

Loss after tax - (29,936) - - (29,936)

Other Comprehensive Income - - - 25 25

TOTAL COMPREHENSIVE LOSS

attributable to equity holders of the

Company

- (29,936) - 25 (29,911)

Transactions with owners in their

capacity as owners:

Share Based Payments- Employee

Remuneration

8 58 - - - 58

Share Based Payment- Employee

Share Options

8 - 63 1,253 - 1,316

Balance as at 31 March 2025 294,458 (276,222) 6,860 989 26,085

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

71

CONSOLIDATED BALANCE SHEET
As at 31 March 2025

For and on behalf of the Board of Directors dated the 29 day of May 2025:

Director Director

Note: These Consolidated Financial Statements are to be read in conjunction with the Notes to the Consolidated Financial Statements

Notes

2025

($000)

2024

($000)

CURRENT ASSETS

Cash and Cash Equivalents9 9,482 29,261

Short Term Deposits9 13,086 21,000

Receivables10 4,970 4,698

Inventory11 1,607 1,688

Other Assets121,679 1,228

Total Current Assets 30,824 57,875

NON-CURRENT ASSETS

Property, Plant and Equipment13 2,980 2,925

Right of Use Assets23 2,445 3,698

Intangible Assets14 781 950

Total Non-Current Assets 6,206 7,573

TOTAL ASSETS 37,030 65,448

CURRENT LIABILITIES

Payables and Accruals17 8,044 6,753

Borrowings 300 300

Lease Liabilities23 1,413 1,264

Total Current Liabilities 9,757 8,317

NON-CURRENT LIABILITIES

Lease Liabilities23 1,188 2,509

Total Non-Current Liabilities 1,188 2,509

TOTAL LIABILITIES 10,945 10,826

NET ASSETS 26,085 54,622

Represented by:

EQUITY

Share Capital18 294,458 294,400

Accumulated Losses (276,222) (246,349)

Share Based Payments Reserve 6,860 5,607

Foreign Translation Reserve 989 964

TOTAL EQUITY 26,085 54,622

FURTHER INFORMATION

Net Tangible Assets per share ($) 0.031 0.066

72

CONSOLIDATED STATEMENT OF CASH FLOWS
For the twelve months ended 31 March 2025

Note: These Consolidated Financial Statements are to be read in conjunction with the Notes to the Consolidated Financial Statements

Notes

2025

($000)

2024

($000)

CASH FLOWS TO OPERATING ACTIVITIES

Cash was provided from:

Receipts from Customers 21,572 24,137

Receipts from Research Tax Incentives and Grant

Providers

677 1,856

Interest Received 2,121 3,441

24,370 29,434

Cash was disbursed to:

Payments to Suppliers and Employees 49,097 55,196

Net GST (inflow) 13 (12)

49,110 55,184

Net Cash Flows To Operating Activities20 (24,740) (25,750)

CASH FLOWS FROM INVESTING ACTIVITIES:

Cash was provided from:

Proceeds from Sale of Plant and Equipment54-

Proceeds from Short Term Deposits 48,000 83,084

48,054 83,084

Cash was disbursed to:

Purchase of Short Term Deposits40,086 59,523

Capital Expenditure on Plant and Equipment 867 832

Capital Expenditure on Intangible Assets 406 540

41,359 60,895

Net Cash Flows From Investing Activities 6,695 22,189

CASH FLOWS TO FINANCING ACTIVITIES:

Cash was provided from:

Proceeds from Borrowings - 300

- 300

Cash was disbursed to:

Security deposited for Credit Cards146-

Repayment of Leases- Principal23 1,266 1,268

Repayment of Leases- Interest23 230 138

1,642 1,406

Net Cash Flows To Financing Activities (1,642) (1,106)

Net Decrease in Cash Held (19,687) (4,667)

Add Opening Cash Brought Forward 29,261 33,229

Effect of exchange rate changes on net cash (92) 699

Ending Cash Carried Forward9 9,482 29,261

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

73

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

1. MATERIAL ACCOUNTING POLICY INFORMATION

Reporting Entity

The consolidated financial statements (hereafter referred to as the ‘financial statements’) presented for the year

ended 31 March 2025 are for Pacific Edge Limited (the ‘Company’) and its subsidiaries (collectively referred to as

the ‘Group’). The Group’s purpose is to research, develop and commercialise new diagnostic and prognostic tools

for the early detection and management of cancers.

Pacific Edge Limited is registered in New Zealand under the Companies Act 1993 and is a Financial Markets

Conduct (FMC) reporting entity under Part 7 of the Financial Markets Conduct Act 2013. The financial statements

of the Group have been prepared in accordance with the requirements of the Financial Markets Conduct Act 2013

and the NZX Listing Rules. The financial statements presented are those of the Group, consisting of the Parent

entity, Pacific Edge Limited and its subsidiaries. The Company is dual listed, with its primary listing of ordinary

shares quoted in New Zealand on the NZX Main Board, and a secondary listing in Australia as a Foreign Exempt

Entity on the ASX.

These financial statements have been approved for issue by the Board of Directors on the 29th May 2025.

Basis of Preparation

These financial statements of the Group have been prepared in accordance with Generally Accepted Accounting

Practice in New Zealand (NZ GAAP). The Group is a Tier 1 for-profit entity for the purposes of complying with

NZ GAAP. The financial statements comply with New Zealand equivalents to International Financial Reporting

Standards (NZ IFRS), other New Zealand accounting standards and authoritative notices that are applicable to

entities that apply NZ IFRS. The financial statements comply with International Financial Reporting Standards

Accounting Standards (“IFRS Accounting Standards”) as issued by the IASB.

The financial statements are presented in New Zealand Dollars, which is the Company’s functional currency and

Group’s presentation currency, and all values are rounded to the nearest thousand dollars ($000). The accounting

principles recognised as appropriate for the measurement and reporting of earnings, cash flows and financial

position on a historical cost basis have been used.

The Consolidated Statement of Comprehensive Income and Consolidated Statement of Cash Flows have been

prepared so that all components are stated net of GST. All items in the Consolidated Balance Sheet are stated net

of GST, with the exception of receivables and payables

Management of Capital

The capital structure of the Group consists of equity raised by the issue of ordinary shares in the Company. The

Company’s objectives when managing capital are to safeguard the Company’s ability to continue as a going

concern in order to provide returns for shareholders, provide benefit for other stakeholders and to maintain an

optimal capital structure to support the development of its business. The Company meets these objectives through

closely managing revenue and expenditure, and where required issues new shares.

Going Concern

The 2025 financial statements have been prepared on a going concern basis which assumes that the Company

will have sufficient cash to pay its debts as they fall due for a minimum of 12 months from the date of signing the

Financial Statements.

As at 31 March 2025, the Company has $22.568m of cash, cash equivalents and short-term deposits (2024:

$50.261m) and net assets of $26.085m (2024: $54.622m). The Company made a net loss after tax of $29.936m

(2024: loss of $29.535m). Net cash out flows from operating activities for the 12 month period to 31 March 2025

were $24.740m (2024: cash outflow $25.750m).

While the Company continues to incur operating losses, the Company remains solvent and continues to meet its

debts as they fall due.

As noted in Note 25 - Subsequent Events, the Company has lost Medicare coverage for Cxbladder tests in the

US from 24 April 2025. These tests generated approximately 56% of Operating Revenue in the year ended 31

March 2025. The Company is seeking to regain coverage through the submission of reconsideration requests for

Cxbladder Triage (made 21 March 2025), and Cxbladder Monitor (submission for reconsideration made May 2025).

Industry experts typically estimate a coverage decision 6-9 months after a submission of a single product with only

a small number of new supporting publications.

74

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

While the loss of Medicare coverage is expected to have a significant impact on testing volume, the Company

expects to continue to bill and receive reimbursement from contracted commercial US payers without interruption,

notably from Kaiser Permanente, the US Veterans Administration, various Blue Cross Blue Shield plans under the

group purchasing agreement and from non-contracted private payers in line with historic reimbursement rates.

The Company will also increase appeals activity, leveraging the February 2025 inclusion of Cxbladder Triage in the

American Urological Association Microhematuria Guideline. Additionally, the Company expects collections from

it’s enhanced patient responsibility and patient assistance programs to continue in line with the rates since the

introduction of that program in July 2023.

Offsetting the negative coverage outcome for Medicare, the inclusion of Cxbladder Triage in the February 2025

American Urological Association Microhematuria Guideline (the only biomarker test included with A Grade

evidence) is expected to drive demand from clinicians in the US and if coverage is resumed, provide increased

volumes and revenue in the United States. Cxbladder Triage Plus, the replacement product for Triage, has also

received draft Gapfill pricing of US$1,018.44 per test. The price for Cxbladder Triage Plus is expected to be made

effective on 1 January 2026, and if covered by Medicare, will be a meaningful increase (when compared to the

US$760 Medicare approved price of our existing tests) because it would increase both the gross margin and gross

margin percentage per test and improves the profitability of operating our front-line sales force.

The Company has prepared cash flow forecasts which indicate that with the Medicare non-coverage decision, the

Company may not have sufficient cash to meet its minimum expenditure commitments and support its current

levels of activity.

To address the future additional funding requirements of the Group, there are a number of options available to the

Directors, including:

• raising additional capital. On 29 May 2025, the Board approved a capital raise which is being progressed with

the intention of raising at least $20m via a Placement and Share Purchase Plan. Completion of the Placement

will be dependent on shareholder approval, with anticipated settlement date no later than 31 August 2025; and

• continuing to monitor the Company’s ongoing working capital requirements and minimum expenditure

commitments, including identifying cost management options to maintain a level of expenditure that is in line

with the Company’s available cash resources.

While the Company is confident about revenue opportunities in the US market and obtaining additional funds via

an equity raise, the Directors acknowledge that there are a number of material uncertainties set out above related

to unknown future events that are not fully in their control. These material uncertainties are related to events and

conditions that may cast significant doubt on the Company’s ability to continue as a going concern and therefore it

may be unable to realise its assets and discharge its liabilities in the normal course of business.

The financial statements do not include any adjustments that may be required if the Group was unable to continue

as a going concern.

Basis of Consolidation

The following entities and the basis of their inclusion for consolidation in these Financial Statements are as follows:

Name of Subsidiary

Place of

Incorporation

(or registration)

& Operation

Principal Activity

Ownership Interests

& Voting Rights

31 March

2025

%

31 March

2024

%

Pacific Edge Diagnostics

New Zealand Limited

New Zealand

Commercial Sales and Diagnostic

Laboratory Operation

100100

Pacific Edge (Australia) Pty

Limited

Australia

Commercial Sales and

Biotechnology Research

& Development

100100

Pacific Edge Diagnostics USA

Limited

USA

Commercial Sales and Diagnostic

Laboratory Operation

100100

Pacific Edge Diagnostics

Singapore Pte Limited

Singapore

Commercial Sales and

Biotechnology Research &

Development. Dissolved and stuck

off 20 February 2025

0100

Pacific Edge Analytical Services

Limited

New ZealandDormant Company100100

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

75

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

The financial statements incorporate the assets, liabilities and results of all subsidiaries of Pacific Edge Limited as at

31 March 2025 and for the year then ended. All subsidiaries have the same balance date as the Company of 31 March.

Pacific Edge Limited consolidates all entities over which Pacific Edge Limited has control. Control is achieved when

the Group:

• has power to direct the activities of the entity;

• is exposed, or has rights, to variable returns from involvement with the entity; and

• has the ability to use its power to affect its returns.

Subsidiaries which form part of the Group are consolidated from the date on which control is transferred to the

Group. They are de-consolidated from the date that control ceases.

The acquisition method of accounting is used to account for business combinations by the Group. The consideration

transferred for the acquisition of a subsidiary is the fair value of the assets transferred, the liabilities incurred and the

equity interest issued by the Group.

The consideration transferred includes the fair value of any asset or liability resulting from a contingent consideration

arrangement. Acquisition-related costs are expensed as incurred. Identifiable assets acquired and liabilities and

contingent liabilities assumed in a business combination are measured initially at their fair values at the acquisition

date. On an acquisition-by-acquisition basis, the Group recognises any non-controlling interest in the acquiree either

at fair value or at the non-controlling interest’s proportionate share of the acquiree’s net assets. Inter-company

transactions, balances and unrealised gains on transactions between Group companies are eliminated. Unrealised

losses are also eliminated. Accounting policies of subsidiaries have been changed where necessary to ensure

consistency with the policies adopted by the Group.

Critical Accounting Estimates and Assumptions

In preparing these financial statements, the Group made estimates and assumptions concerning the future.

These estimates and assumptions may differ from the subsequent actual results. Estimates and assumptions are

continually evaluated and are based on historical experience and other factors including expectations or future

events that are believed to be reasonable under the circumstances.

The Group has performed an assessment of potential climate related risks and considered the location of

laboratories and other key operations in each region that it operates in and concluded that there is no material

impact on the current financial statements.

All other material accounting policy information has been applied on a basis consistent with those used in the

audited financial statements of Pacific Edge Limited for the year ended 31 March 2025.

2. NEW STANDARDS

NEW DISCLOSURE REQUIREMENTS AND CHANGES IN ACCOUNTING STANDARDS ADOPTED BY THE GROUP

Disclosure of Fees for Audit Firms’ Services (Amendments to FRS-44)

The amendments to FRS-44 aim to address concerns about the quality and consistency of disclosures an entity

provides about fees paid to its audit firm for different type of services. 

Application of this amendment is required for accounting periods beginning on or after 1 January 2024. The Group

has adopted these amendments to FRS-44 in the 2025 financial statements.

The IFRIC have released an agenda decision on Segment Reporting providing details on how an entity applies the

requirements in paragraph 23 of IFRS Operating Segments. The agenda decision does not have a material impact

in the 2025 financial statements.

There are no other NZ IFRS or NZ IFRIC interpretations that are effective that would be expected to have a

material impact on the Group.

76

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

NEW STANDARDS AND INTERPRETATIONS NOT YET ADOPTED BY THE GROUP

The following new accounting standards and interpretations have been published that are not mandatory for

31 March 2025 reporting periods and have not been early adopted by the Group. 

NZ IFRS 18 Presentation and Disclosure in Financial Statements (IFRS 18)

NZ IFRS 18 Presentation and Disclosure in Financial Statements (IFRS 18) was issued in May 2024 as replacement

for IAS 1 Presentation of Financial Statements (IAS 1). Most of the presentation and disclosure requirements would

largely remain unchanged together with other disclosures carried forward from IAS 1 IFRS 18 primarily introduces

the following:

• a defined structure for the consolidated statement of comprehensive income by classifying items into one

of the five categories: operating, investing, financing, income taxes and discontinued operations. Entities will

also present expenses in the operating category by nature, function, or a mix of both, based on facts and

circumstances;

• disclosure of management-defined performance measures non-GAAP measures in a single note together with

reconciliation requirements, and

• additional guidance on aggregation and disaggregation principles (applied to all primary financial statements

and notes).

IFRS 18 also made limited change to certain presentation and disclosure requirements in the financial statements;

as well as consequential changes to various IFRS Accounting Standards.

IFRS 18 will be effective for annual reporting periods beginning on or after 1 January 2027 and entities could

early adopt this accounting standard. The Group expects to adopt IFRS 18 and relevant consequential changes of

other accounting standards in the 2028 financial statements. The Group is currently assessing the impact and will

disclose more detailed assessments in the future.

3. EARNINGS PER SHARE

(a) Basic

Basic earnings per share is calculated by dividing the profit (or loss) attributable to equity holders of the Company

by the weighted average number of ordinary shares on issue during the year excluding ordinary shares purchased

by the Company (Note 18).

GROUP

20252024

Loss attributable to equity holders of the Company($000)(29,936) (29,535)

Weighted average number of ordinary shares on issue(000) 811,736 810,727

Earnings per share($) (0.037) (0.036)

(b) Diluted

Diluted earnings per share is calculated by adjusting the weighted average number of shares outstanding to

assume conversion of all dilutive potential ordinary shares. The Group’s dilutive potential ordinary shares are in the

form of share options. As the Group made a loss during the current year and losses cannot be diluted, basic and

diluted earnings per share are the same.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

77

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

4. LABORATORY THROUGHPUT AND COMMERCIAL TESTS –

NON-GAAP REPORTING

Laboratory Throughput is a key metric for the Group: Laboratory Throughput provides evidence of the usage

of Cxbladder products globally and the rates of adoption between different customer segments. The inclusion

of this non-GAAP reporting is considered helpful to readers of these financial statements, as it allows readers

to compare the current period to prior periods and assess usage trends on a consistent basis. Total laboratory

throughput includes commercial tests, which are invoiced to customers (including tests for patients covered by

the US government’s medical program through the Centers for Medicare and Medicaid Services (CMS)), and

tests which are not considered to be commercial as these tests relate to Research Tests or other non-chargeable

activities.

Commercial Test numbers are also a key metric for the Group: Commercial Tests are those tests for which the

Company is actively seeking reimbursement and cash receipts, and tests performed at no charge in order to

gain new customers. The inclusion of this non-GAAP reporting is considered helpful to readers of these financial

statements as it allows readers to compare the current period to prior periods and assess trends on a consistent

basis.

Laboratory Throughput and Commercial Tests per financial year are shown below.

FY25FY24

Total Laboratory Throughput (tests) 28,894 32,633

Increase (Decrease) in Total Laboratory Throughput (%) (11%)3%

Increase (Decrease) in Throughput from previous year (tests)(3,739) 1,068

Total Commercial Tests (tests) 24,642 27,347

Increase (Decrease) in Commercial Tests from previous year (%)(10%)2%

Increase (Decrease) in Commercial Tests from previous year (tests)(2,705) 656

Commercial Tests as a percentage of Total Laboratory Throughput (%)85%84%

5. REVENUE

Background information on US customers and the payment process

A physician orders a Cxbladder test when a patient presents to their clinic with symptoms that indicate the

possibility of bladder cancer. The most common and significant symptom is haematuria or blood in their urine.

A urine sample is collected from the patient and sent in the Cxbladder Urine Sampling System to the Group’s

laboratory in the US or in New Zealand. The Group receives and processes the urine sample and returns the results

of the test back to the ordering physician. The individual patient is the Group’s customer, however typically in the

US market, the patient’s insurer may pay the Group for some or all of the cost of the test.

When a physician orders a Cxbladder test, the Group has an obligation to perform the test and report the results to

the ordering physician irrespective of the patient’s insurance contract. A patient may have private insurance cover,

be covered by the US government’s medical program through CMS, self cover or have no insurance cover.

Once the Cxbladder test has been completed, all information required for insurance purposes is sent to the Group’s

billing and reimbursement agent to begin the process to collect reimbursement from any applicable insurance

companies for the Cxbladder test performed.

For patients with private insurance cover, the relevant patient and test order information will be sent to their

insurance provider. When the Group does not have an individual agreement with that insurance provider to pay

for Cxbladder tests (“out of network”), the insurance provider will assess that individual patient’s test for medical

necessity and the level of insurance cover (if any) available to cover the cost of the test. This process of assessment

can take many months to work through before the Group receives payments (if any) from the insurance company.

The Group does have agreements with some insurance providers but these currently cover a small proportion of

the Group’s customers.

78

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

For patients covered by CMS, invoices are sent to CMS. Prior to 3 July 2020, Pacific Edge was not included in the

Local Coverage Determination (LCD) and as a result, did not normally receive any amounts for tests performed

for patients covered by CMS. On 3 July 2020, Pacific Edge received notice of inclusion in the LCD, resulting in

the Company receiving reimbursement for Cxbladder Monitor and Detect tests performed after 1 July 2020 for

patients covered by the CMS across the US that are deemed medically necessary.

For uninsured patients, the Group has no certainty of when or if the patient will pay.

Refer to note 25 - Subsequent Events for details on the Local Coverage Determination change that has the

potential to negatively impact future revenue.

Rest of World Customers

Revenue from Rest of World customers is primarily from Te Whatu Ora Health New Zealand. In all Rest Of World

locations, there is a clearly defined contract with the customer meeting the requirements of NZ IFRS 15. Pacific

Edge Diagnostics New Zealand Limited has individual contracts with regions across New Zealand and revenue is

recognised as described on the following pages.

Critical Accounting Estimate

The application of NZ IFRS 15: Revenue from contracts with customers (NZ IFRS 15) requires the application of

significant judgement in determining whether the Group meets the five key criteria identified in NZ IFRS 15, which

allows revenue to be recognised as performance obligations are satisfied. For the Group this would result in some

revenue recognised in advance of the receipt of cash.

The significant judgements adopted by the Group relate to :

- determining if a contract with the customer exists;

- identifying the rights of each party;

- identifying the payment terms;

- ensuring the contract has commercial substance; and

- determining whether it is probable that the Group will collect the consideration to which it is entitled.

While there has been significant judgement applied to all five criteria, there are two criteria that have higher levels

of uncertainty, requiring increased levels of judgement. The significant judgements applied to determine the

Transaction Price and determining the probability of collecting consideration are detailed in the Accounting Policy

relating to Revenue from Cxbladder Tests.

ACCOUNTING POLICY

Revenue from Cxbladder tests – USA

The Group performs Cxbladder tests when requested by a patient’s physician. At the point the test results are

returned to the physician, the Group has satisfied its performance obligation and has the right to issue an invoice.

Revenue can be recognised at this point in time. On return of the test result, the Group has determined a contract

exists, that the payment terms are identified, that the contract has commercial substance and there has been

identification of the rights of each party.

On the 3 July 2020, Pacific Edge received notice of inclusion in the LCD, resulting in the Company receiving

reimbursement for Cxbladder Monitor and Detect tests performed after 1 July 2020 for patients covered by

the CMS across the US that are deemed medically necessary. Reimbursement for these tests is at the already

determined national CMS price for Cxbladder of US$760 per test, less a 2% sequestration fee.

Since Cxbladder’s inclusion in the LCD, based on historical data, the Group has been able to reliably estimate

both the probability and size of payment received from the CMS. The inclusion within the LCD combined with the

growing support for the use of Cxbladder within the US has also allowed the Group to reliably estimate both the

probability and size of payment received from customers covered by Medicare Advantage policies provided by

private insurers and customers covered by Kaiser Permanente.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

79

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

Tests performed for patients covered by other private policies, or tests performed for those with no insurance

cover continue to be recognised as revenue when cash is collected and the Group has satisfied its performance

obligations and that the contract is considered terminated and the amount received is non-refundable. Revenue

is recognised on a cash basis is due to not being able to reliably estimate both probability and size of payment

received. Management continually re-assess its probability to collect payments to be able to account for the

transaction under NZ IFRS 15.

The Group have concluded that the contracts with the CMS and customers covered by Medicare Advantage and

Kaiser Permanente include variable consideration because the amounts paid by Medicare, Kaiser Permanente or

the commercial health insurance carriers that provide Medicare Advantage may be paid at less than our standard

rates or not paid at all, with such differences considered implicit price concessions. Variable consideration

attributable to these price concessions is measured at the expected value, and are determined by historical average

collection rates by test type and payor category taking into consideration the range of possible outcomes and

predictive value of our past experiences. Such variable consideration is included in the transaction price only to the

extent it is probable that a significant reversal in the amount of cumulative revenue recognised will not occur.

As a result of the Significant Judgements applied, the Group have determined the criteria under NZ IFRS 15 which

allows revenue to be recognised in advance of the receipt of cash have been met, and the Group has recognised

revenue for tests which were performed from 1 October 2024 to 31 March 2025 (6 months prior to balance date)

for which payment has not been received by 31 March 2025 from CMS and Medicare Advantage. Following a

change in commercial agreement, revenue for Kaiser Permanente is recognised in the month the test is performed.

Rest of World revenue recognition from tests performed

There has been no change in accounting policy or estimates for Operating Revenue for the Rest of World. The

Group performs Cxbladder tests when requested by a patient’s physician in New Zealand, Australia and Southeast

Asia. At the point the test results are returned to the physician, the Group has satisfied its performance obligation.

At the end of the month an invoice is issued to the customer based on the number of tests performed. Revenue is

recognised when the invoice is issued.

OTHER INCOME

Grant Income

Government Grants are not recognised until there is reasonable assurance that the Group will comply with the

conditions attached to them and that the grants will be received. Government Grants are recognised in Other

Income in the consolidated Statement of Comprehensive Income, on a systematic basis over the periods in which

the Group recognises the related costs as expenses for which the grants are intended to compensate.

The Company receives grants from Callaghan Innovation for postgraduate internships and summer students.

All conditions of the grants have been complied with.

Research Rebates and Tax Incentives

- New Zealand R&D Tax Incentive (RDTI)

The New Zealand RDTI is a 15% tax credit on the money invested in eligible research and development (R&D) that

has occurred in New Zealand. As the New Zealand companies are in a tax loss position, the Group is eligible for the

Tax Incentive to be refunded.

The RDTI is recognised at its fair value where there is a reasonable assurance that the credit will be received and

the Group will comply with all attached conditions.

All conditions of the New Zealand RDTI have been complied with. Payment will be received after submission of

each annual research and development tax claim.


80

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

- Australia Cxbladder Research Rebate

A Cxbladder research programme is administered by Pacific Edge (Australia) Pty Limited and tax rebates are

received as a result of this programme.

The Cxbladder research rebate is recognised at its fair value where there is a reasonable assurance that the rebate

will be received and the Group will comply with all attached conditions.

For the year ended 31 March 2025, Group revenue is over $20m Australian Dollars, resulting in research rebates

being issued as a tax credit. The Tax Credit is not recognised as a tax asset in the financial statements for the year

ended 31 March 2025.

REVENUE AND OTHER INCOME

2025

($000)

2024

($000)

Cxbladder Sales

– US - Accrual Accounting 17,517 19,288

– US - Cash Accounting 2,565 3,214

– Total US Sales 20,082 22,502

– Rest Of World 1,764 1,405

Total Operating Revenue 21,846 23,907

Other Income

Grant Revenue 22 24

Research Rebates and Tax Incentives 881 1,298

Total Other Income 903 1,322

6. RESEARCH AND DEVELOPMENT COSTS

ACCOUNTING POLICY

Research is the original and planned investigation undertaken with the prospect of gaining new scientific

knowledge and understanding. This includes: direct and overhead expenses for diagnostic and prognostic

biomarker discovery and research; pre-clinical trials; and costs associated with clinical trial activities. All research

costs are expensed when incurred.

Development is the application of research findings to a plan or design for the production of new or substantially

improved processes or products prior to the commencement of commercial production.

When a project reaches the stage where it is probable that future expenditure can be recovered through the

process or products produced, expenditure that is directly attributed or reasonably allocated to that project is

recognised as a development asset within intangible assets. If the expenditure also benefits processes or products

for which it cannot be recovered, it will be expensed. The asset will be amortised from the date of commencement

of commercial production of the product to which it relates on a straight-line basis over the period of expected

benefit. Development assets are reviewed annually for any impairment in their carrying value.

GROUP

Notes

2025

($000)

2024

($000)

Research Expenses 14,631 12,089

Includes:

Employee Benefits8 7,775 6,571

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

81

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

7. GENERAL AND ADMINISTRATION EXPENSES

GROUP

Notes

2025

($000)

2024

($000)

Amortisation14 286 311

Auditors Remuneration: PricewaterhouseCoopers New Zealand

- Group year end financial statements

- Half year review of financial statements

- Travel costs

198

35

10

194

34

22

Other assurance services provided by PricewaterhouseCoopers

New Zealand

- Assurance on Carbon Emissions - Scope 1 and 2 30-

Other services provided by PricewaterhouseCoopers New Zealand

- Financial Training Workshops12

Depreciation13 420 358

Depreciation on Right of Use Assets23 206 195

Directors Fees22 470 500

Employee Benefits8 4,694 3,974

Insurance 634 610

Interest on Lease Liabilities23 35 21

Legal Fees 611 826

NZX, ASX and Registry Fees 230 274

Other Operating Expenses 2,041 2,077

9,901 9,398

Note: Amounts displayed for Amortisation, Depreciation, Employee Benefits are only the General and Administration Expenses

component of the total expenses. Refer to relevant notes for full expense disclosure.

Other Operating Expenses

The major categories of expenditure which make up General and Administration Expenses, but are not disclosed

separately above are Information Technology costs, Compliance and Regulatory costs, Investor Relations costs,

Consultants and Contractors.

82

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

8. EMPLOYEE BENEFITS

GROUP

Notes

2025

($000)

2024

($000)

Represented by:

Cash Employee Benefits:

Lab Operations 3,6193,119

Research67,7756,571

Sales and Marketing11,55516,697

General and Administration74,6943,974

Total Employee Benefits27,64330,361

Employee Share Scheme

The Company has an Employee Share Scheme where ordinary shares in the Company may be issued to selected

employees to recognise performance or a significant contribution to the Company. These shares may be issued

in lieu of a cash bonus or in addition to the employee’s remuneration. The ordinary shares are issued directly to

the employee and the Company accounts for the cost of the shares. The shares are allocated to the employee on

the date that the Board approves the issue of the share capital. All employees who hold ordinary shares in the

Company must comply with the Company’s Share Trading Policy.

The issuance of ordinary shares to employees is treated as equity settled share-based payments. Equity-settled

share-based payments to employees are measured at the fair value of the equity instruments at the grant date

based on the market price at the time of issuance. The fair value of shares granted is recognised as an employee

expense in the Consolidated Statement of Comprehensive Income when the shares are issued. During the 2025

financial year, 644,630 (2024: 906,000) ordinary shares were issued to employees as part of the Employee Share

Scheme. The associated non-cash cost of these shares was $58,000 (2024: $83,000). Refer to Note 18 for further

details on the shares issued during the financial year.

Attract and Retain Options

The Board believes that the issue of share options provides an appropriate incentive for participating employees to

grow the total shareholder return of the Company.

Attract and retain options are issued to selected employees as a long-term component of remuneration in

accordance with the Group’s remuneration policy. Incentive Options entitle the holder, on payment of the exercise

price, to one ordinary share of the Company.

The exercise price of the granted options is determined using the fair value of the Company’s share price at the

time of the options being granted.

Incentive Options issued prior to 31 March 2022 generally vest over three years and contain the requirement to

remain as an employee of the Company in order for the options to vest. Tranches of options are exercisable over

four to ten years from the relevant vesting date. No options can be exercised later than the tenth anniversary of the

final vesting date.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

83

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

Options issued after 1 April 2022 to 31 March 2024 generally vest equally in three tranches over a four year period,

with 1/3 on the second, third and fourth anniversary of the issue. The Options are exercisable up to four years after

vesting date. Option holders are required to remain as an employee of the Company in order for options to vest.

No options can be exercised later than the fourth anniversary of the final vesting date. The exercise price increases

annually for each vested tranche at the equity cost of capital.

Options issued after 1 April 2024 generally vest equally in in three tranches over a three year period, with 1/3 on

the first, second and third anniversary of the issue. The Options are exercisable up to four years after vesting date.

Option holders are required to remain as an employee of the Company in order for options to vest. No options can

be exercised later than the fourth anniversary of the final vesting date. The exercise price increases annually for

each vested tranche at the equity cost of capital.

ACCOUNTING POLICY

All options are accounted for as equity settled share based payments as the Group has no legal or constructive

obligation to repurchase or settle in cash. The fair value of all options granted is recognised as an expense in the

Consolidated Statement of Comprehensive Income over their vesting period, with a corresponding increase in

the employee share option reserve. The options expense for the year ended 31 March 2025 was $1,316,819 (2024:

$1,189,000).

The fair value is determined at the grant date of the options and expensed on a straight-line basis over the vesting

period, based on the Group’s estimate of equity instruments that will eventually vest, with a corresponding increase

in equity. At the end of each reporting period, the Group revisits its estimate of the number of equity instruments

expected to vest. The impact of the revision of the original estimates, if any, is recognised in the Consolidated

Statement of Comprehensive Income such that the cumulative expense reflects the revised estimate, with a

corresponding adjustment to the share based payments reserve.

During the financial year ended 31 March 2025, there were no share options exercised (2024: Nil). There was no

resulting increase in share capital (2024: $Nil).

Movements in the number of options outstanding and their related weighted average exercise prices are as follows:

GROUP

20252024

Weighted average

exercise price

$

Options

#

Weighted average

exercise price

$

Options

#

Outstanding at 1 April 0.45 31,892,174 0.59 17,765,038

Granted0.12 9,165,532 0.30 14,711,546

Forfeited 0.33 (635,939)0.59 (584,410)

Expired 0.69 (95,000)- -

Outstanding at 31 March0.38 40,326,767 0.45 31,892,174

Exercisable at 31 March0.52 14,435,570 0.44 12,635,479


The Group used the Black-Scholes valuation model to determine the fair value of the equity instruments granted.

The Black-Scholes valuation model has been determined as the most appropriate method as it estimates the

theoretical value of options taking into account the impact of time and other risk factors. The significant inputs into

the Black-Scholes valuation model were the market share price at grant date, the exercise price shown below, the

expected annualised volatility of 50-106%, a dividend yield of 0%, an expected option life of between one and ten

years and an annual risk-free interest rate of between 0.65% and 5.63%.

The volatility measured is the standard deviation of continuously compounded share returns and is based on a

statistical analysis of daily share prices in the past one to ten years.

84

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

Share options outstanding at the end of the reporting periods have the following expiry dates, vesting dates,

exercise prices and movements for the year ended 31 March 2025:

IssuedExpiryLow Exercise Price ($)High Exercise Price ($)Weighted Average Exercise Price ($)Opening Options as at 1 April 2024IssuedForfeitedExercisedExpiredClosing Options 31 March 2025Exercisable as at 31 March 2025

Apr 2014 -

Mar 2015

Sept 2024 -

Jan 2028

0.69 0.72 0.71 528,441 - - - (95,000) 433,441 433,441

Apr 2015 -

Mar 2016

Sept 2025 -

Mar 2029

0.50 0.60 0.51 332,399 - - - - 332,399 332,399

Apr 2016 -

Mar 2017

Nov 2026 -

Jan 2030

0.48 0.60 0.57 327,607 - - - - 327,607 327,607

Apr 2017 -

Mar 2018

May 2028 -

Feb 2031

0.28 0.51 0.50 2,770,899 - - - - 2,770,899 2,770,899

Apr 2018 -

Mar 2019

Jun 2029 -

Nov 2031

0.23 0.28 0.24 69,098 - - - - 69,098 69,098

Apr 2019 -

Mar 2020

Aug 2030 -

Aug 2032

0.23 0.23 0.23 4,037,267 - - - - 4,037,267 4,037,265

Apr 2020 -

Mar 2021

Jun 2031 -

Jun 2033

0.22 0.80 0.31 2,142,108 - - - - 2,142,108 2,142,108

Apr 2021 -

Mar 2022

Aug 2032 -

Aug 2034

1.23 1.23 1.23 342,404 - (1,315) - - 341,089 341,090

Apr 2021 -

Mar 2022

Feb 2027 -

Feb 2031

1.15 1.25 1.23 3,000,000 - - - - 3,000,000 1,800,000

Apr 2022 -

Mar 2023

Dec 2026 -

Dec 2030

0.48 0.70 0.60 3,722,605 - (73,868) - - 3,648,737 2,181,662

Apr 2023 -

Mar 2024

Apr 2029 -

Oct 2031

0.25 0.64 0.30 14,619,346 - (560,756) - - 14,058,590 -

Apr 2024 -

Mar 2025

Jul 2029 -

Dec 2031

0.10 0.17 0.12 - 9,165,532 - - - 9,165,532 -

TOTALS0.38 31,892,174 9,165,532 (635,939) - (95,000) 40,326,767 14,435,570

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

85

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

9. CASH, CASH EQUIVALENTS AND SHORT TERM DEPOSITS

ACCOUNTING POLICY

Cash and cash equivalents includes cash in hand and deposits held on call with banks, and bank overdrafts. Term

deposits are also presented as cash equivalents if they have a maturity of three months or less from acquisition

date.

Short Term Deposits and Cash Equivalents include investments with ANZ, BNZ, Kiwibank, Westpac and Wells

Fargo (2024: ANZ, BNZ, Kiwibank and Westpac and Wells Fargo), with periods ranging up to 365 days. Funds held

on term deposit with ANZ, BNZ Westpac and Kiwibank can be accessed with one month’s notice at the request of

the authorised bank signatories of Pacific Edge Limited, but may incur fees and/or charges for early access.


GROUP

2025

($000)

2024

($000)

Cash and Cash Equivalents9,48229,261

Short Term Deposits13,08621,000

Total Cash, Cash Equivalents and Short Term Deposits22,56850,261

NZD17,98242,814

USD4,4936,010

AUD801,436

EUR131

Total Cash, Cash Equivalents and Short Term Deposits22,56850,261

INTEREST INCOME

ACCOUNTING POLICY

Interest income is recognised using the effective interest method.

Interest on the bank balances ranges from 0% to 5.70% (2024: 0% to 6.49%) per annum.

86

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

10. RECEIVABLES

ACCOUNTING POLICY

Receivables are initially measured at fair value and subsequently measured at amortised cost using the effective

interest rate method, less any provision for impairment. An allowance for impairment is made up of expected

credit losses based on the assessment of the trade receivables debt at the individual level for impairment, plus an

additional allowance on the remaining balance for potential credit losses not yet identified.

GROUP

2025

($000)

2024

($000)

Trade Receivables 2,825 2,551

Sundry Debtors 1,903 1,722

Accrued Interest 178 375

GST Refund Due 64 50

Total Receivables 4,970 4,698

There is no provision for impairment relating to the revenue from Cxbladder sales in New Zealand. All outstanding

sales are current and there are no expected credit losses on the amounts outstanding at balance date.

US Trade Receivables includes a provision for future refunds of $263,000 (2024: $83,000).

Sundry Debtors include accruals for grants and rebates that have not yet been paid. These are expected to be paid

once the relevant claims have been submitted. The Company has met all conditions of the claims and there is no

indication that there is impairment of these balances.

Included in trade receivables are the below amounts which were past due but not impaired. These relate to a

number of customers for whom there is no history of default.

GROUP

2025

($000)

2024

($000)

3 to 6 Months 280 75

Over 6 Months 261 267

Total Overdue Trade Receivables 541 342

The foreign currency split of Receivables is:

GROUP

2025

($000)

2024

($000)

NZD 2,301 2,355

USD 2,643 2,334

AUD 26 9

Total Receivables 4,970 4,698

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

87

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

11. INVENTORY

ACCOUNTING POLICY

Inventories are stated at the lower of cost and net realisable value. Cost is determined using the weighted average

formula.

GROUP

2025

($000)

2024

($000)

Laboratory Supplies 1,607 1,688

Total Inventory 1,607 1,688

The major items of Inventory are laboratory reagents, chemicals and Cxbladder urine sampling systems.

Laboratory supplies used during the year of $2,672,000 (2024: $2,769,000) are included within the Consolidated

Statement of Comprehensive Income in Laboratory Operations and Research.

12. OTHER ASSETS

GROUP

2025

($000)

2024

($000)

Prepayments

1,239 979

Security Deposits

440 249

Total Other Assets

1,679 1,228

Prepayments are largely made up of insurance, industry conferences and subscriptions. Security deposits are paid to

secure properties for lease in the US and to secure credit cards in the US.

13. PROPERTY, PLANT AND EQUIPMENT

ACCOUNTING POLICY

Property, Plant and Equipment are those assets held by the Group for the purpose of carrying on its business activities

on an ongoing basis. All Property, Plant and Equipment is stated at cost less subsequent accumulated depreciation

and any accumulated impairment losses. The cost of purchased assets includes the original purchase consideration

given to acquire the assets, and the value of other directly attributable costs that have been incurred in bringing the

assets to the location and condition necessary for their intended service. This includes the laboratory equipment for

the establishment of the laboratories.

Gains and losses on disposals are determined by comparing the net proceeds with the carrying amount and are

recognised within the Consolidated Statement of Comprehensive Income when they occur.

Depreciation

Depreciation of plant and equipment is based on writing off the assets over their useful lives, using the straight line

(SL) and diminishing value (DV) basis.

Main rates used are:

Plant and Laboratory Equipment 5% to 40% DV

Computer Equipment 5% to 67% DV

Leasehold Improvements 6% to 10% SL

Furniture and Fittings 5% to 25% DV

The assets’ useful lives are reviewed, and adjusted if appropriate, at the end of each reporting period.

88

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025


Plant &

Laboratory

Equipment

($000)

Computer

Equipment

($000)

Leasehold

Improvements

($000)

Furniture

& Fittings

($000)

Total

($000)

Cost

Balance at 1 April 20233,4415973962714,705

Additions 731 89111 832

Disposals (213) (29) (1) (11) (254)

Translation difference71117-89

Balance at 31 March 20244,0306684032715,372

Balance at 1 April 20244,0306684032715,372

Additions 704 146 - 17 867

Disposals (268) (66) - (13) (347)

Translation difference 108 12 8 1 129

Balance at 31 March 20254,5747604112766,021

Accumulated Depreciation

Balance at 1 April 2023 1,367 249 197 124 1,937

Depreciation expense 498 155 35 28 716

Disposals (211) (19) - (9) (239)

Translation difference 23 5 5 - 33

Balance at 31 March 20241,6773902371432,447

Balance at 1 April 2024 1,677 390 237 143 2,447

Depreciation expense 661 140 36 24 861

Disposals (251) (53) - (11) (315)

Translation difference 36 7 5 - 48

Balance at 31 March 2025 2,123 484 278 156 3,041

Carrying Amounts

At 1 April 2023 2,074 348 199 147 2,768

At 31 March 2024 2,353 278 166 128 2,925

At 31 March 2025 2,451 276 133 120 2,980

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

89

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

14. INTANGIBLE ASSETS

ACCOUNTING POLICY

Intellectual Property

The costs of acquired Intellectual Property are recognised at cost. All Intellectual Property has a finite life.

The carrying value of Intellectual Property is reviewed for impairment, where indicators of impairment exist.

Amortisation is charged on a diminishing value basis over the estimated useful life of the intangible assets (1-20

years). The estimated useful life and amortisation method is reviewed at the end of each reporting period.

The following costs associated with Intellectual Property are expensed as incurred during the research phases of

a project and are only capitalised when incurred as part of the development phase of a process or product within

development assets: Internal Intellectual Property costs including the costs of patents and patent application.

Software Development Costs

Costs associated with the development of software are held at cost. Amortisation is charged on a diminishing value

basis over the estimated useful life of the intangible assets (2-10 years). The estimated useful life and amortisation

method is reviewed at the end of each reporting period.


Software

Development

Costs

($000)

Patents

($000)

Total

($000)

Cost

Balance at 1 April 20232,1686232,791

Additions5337540

Foreign Translation Difference3 - 3

Balance at 31 March 20242,7046303,334

Balance at 1 April 20242,7046303,334

Additions406-406

Disposals(42)

-

(42)

Foreign Translation Difference2-2

Balance at 31 March 20253,0706303,700

Accumulated Amortisation

Balance at 1 April 20231,2974631,760

Amortisation expense56754621

Foreign Translation difference3 - 3

Balance at 31 March 20241,8675172,384

Balance at 1 April 20241,8675172,384

Amortisation expense54130571

Disposals(38)

-

(38)

Foreign Translation difference2

-

2

Balance at 31 March 20252,3725472,919

Carrying Amounts

At 1 April 20238711601,031

At 31 March 2024837113950

At 31 March 202569883781

90

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

15. SEGMENT INFORMATION

Operating segments are reported in a manner consistent with the internal reporting provided to the chief operating

decision-maker. The chief operating decision-maker, who is responsible for allocating resources and assessing

performance of the operating segments, has been identified as the Chief Executive Officer who makes strategic

decisions.

There are two operating segments at balance date:

1. Commercial: The sales, marketing, laboratory and support operations to run the commercial businesses worldwide.

2. Research: The research and development of diagnostic and prognostic products for human cancer.

The reportable operating segment Commercial derives its revenue primarily from sales of Cxbladder tests and

the reportable operating segment Research derives its revenue primarily from grant income. The Chief Executive

Officer assesses the performance of the operating segments based on their net loss for the period.

Segment income, expenses and profitability are presented on a gross basis excluding inter-segment eliminations

to best represent the performance of each segment operating as independent business units. The segment

information provided to the Chief Executive Officer for the reportable segment described above, for the year

ended 31 March 2025, is shown below.

2025

Commercial

($000)

Research

($000)

Less:

Eliminations

($000)

Total External

Income

($000)

Income

Operating Revenue – External21,852 - (6)21,846

Other Income1,2374,757 (5,091)903

Interest Income121,913 - 1,925

Foreign Exchange Gain (2) (56) - (58)

Total Income23,0996,614 (5,097)24,616

Expenses

Other Expenses19,6369,612 (5,097)24,151

Employee Benefits16,53211,111 - 27,643

Depreciation & Amortisation 1,864 894 - 2,758

Total Operating Expenses38,03221,617 (5,097)54,552

Loss Before Tax (14,933) (15,003)- (29,936)

Income Tax Expense - - - -

Loss After Tax (14,933) (15,003) - (29,936)

Net Cash Flow to Operating Activities (13,031) (11,709) - (24,740)

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

91

2024
Commercial

($000)

Research

($000)

Less:

Eliminations

($000)

Total External

Income

($000)

Income

Operating Revenue – External 23,871 - 36 23,907

Other Income 489 4,400 (3,567) 1,322

Interest Income 21 3,412 - 3,433

Foreign Exchange Gain 1 666 (36) 631

Total Income 24,382 8,478 (3,567) 29,293

Expenses

Other Expenses 19,048 10,379 (3,567) 25,860

Employee Benefits 20,960 9,402 - 30,362

Depreciation and Amortisation 1,629 977 - 2,606

Total Operating Expenses 41,637 20,758 (3,567) 58,828

Loss Before Tax (17,255) (12,280) - (29,535)

Income Tax Expense - - - -

Loss After Tax (17,255) (12,280) - (29,535)

Net Cash Flow to Operating Activities (14,447) (11,303) - (25,750)

Eliminations

These are the intercompany transactions between the subsidiaries and the Parent. These are eliminated on

consolidation of Group results. The Research segment of the business utilise consumables and other components

that are purchased by the Commercial segments of the business, with the costs of these components allocated to

Research segment, and the Commercial segment recognising revenue from the sale.

Segment Assets and Liabilities Information

2025

Commercial

($000)

Research

($000)

Total

($000)

Total Assets 11,257 25,773 37,030

Total Liabilities 6,449 4,496 10,945


2024

Commercial

($000)

Research

($000)

Total

($000)

Total Assets 11,443 54,005 65,448

Total Liabilities 6,871 3,955 10,826

Additions to Non Current Assets for the period include:

Commercial

($000)

Research

($000)

Total

($000)

Property, Plant and Equipment 863 4 867

Right of Use Assets - - -

Intangible Assets 406 - 406

Total Additions to Non Current Assets 1,269 4 1,273

The amounts provided to the Chief Executive Officer with respect to total assets and total liabilities are measured

in a manner consistent with that of the financial statements. These assets and liabilities are allocated based on the

operation of the segment and the physical location of the asset.

There are no unallocated assets or liabilities.

Notes to the Consolidated Financial Statements

For the twelve months ended 31 March 2025

92

Geographic Split of Revenue and Non-Current Assets
The Group generates most of the operating revenue from Commercial tests from the US and New Zealand and also

receives Grant revenue from New Zealand. Rest of World consists of Revenue from Australia and Southeast Asia.


2025

($000)

2024

($000)

Operating and Grant Revenue

US 20,143 22,502

New Zealand 2,499 2,641

Rest of World 107 86

Total Operating and Grant Revenue 22,749 25,229

2025

($000)

2024

($000)

Non-Current Assets

US 3,455 4,343

New Zealand 2,750 3,229

Rest of World 1 1

Total Non-Current Assets 6,206 7,573

16. INCOME TAX

ACCOUNTING POLICY

The tax expense for the period comprises current and deferred tax. Tax is recognised in the Consolidated

Statement of Comprehensive Income, except to the extent that it relates to items recognised in other

comprehensive income or directly in equity. In this case, the tax is also recognised in other comprehensive income

or directly in equity, respectively.

The current income tax charge is calculated on the basis of the tax laws enacted or substantively enacted at the

balance sheet date in the countries where the Company and its subsidiaries operate and generate taxable income.

Management periodically evaluates positions taken in tax returns with respect to situations in which applicable

tax regulation is subject to interpretation. It establishes provisions where appropriate on the basis of amounts

expected to be paid to the tax authorities.

Deferred income tax is provided in full, using the liability method, on temporary differences arising between the

tax bases of assets and liabilities and their carrying amounts in the financial statements in accordance with NZ

IAS 12. Deferred income tax assets are recognised to the extent that it is probable that future taxable profit will be

available against which the temporary differences can be utilised.

Deferred income tax is determined using tax rates (and laws) that have been enacted or substantially enacted by

the balance sheet date and are expected to apply when the related deferred income tax asset is realised or the

deferred income tax liability is settled.

The Company and Group has incurred an operating loss for the 2025 financial year and no income tax is payable.

Notes to the Consolidated Financial Statements

For the twelve months ended 31 March 2025

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

93

GROUP
2025

($000)

2024

($000)

Income tax recognised in the Consolidated Statement of

Comprehensive Income


Current tax expense - -

Deferred Tax in respect of the Current Year (4,366) (3,217)

Adjustments to deferred tax in respect to Prior Years 1,232 284

Deferred Tax Assets not recognised 3,134 2,933

Income tax expense - -


The prima facie income tax on Pre-Tax Accounting Profit

from operations reconciles to:

Accounting loss before income tax (29,936) (29,535)

At the statutory Income Tax rate of 28% (8,382) (8,270)

Non-deductible Expenses 4,764 5,959

Difference in US and Australian Income Tax Rates 891 897

Prior Period Adjustment 1,232 284

Tax Losses Utilised (1,639) (1,803)

Deferred Tax Assets not recognised 3,134 2,933

Income tax expense reported in the Consolidated Statement

of Comprehensive Income

- -

Tax Losses

The Group has losses to carry forward of approximately $169,288,000 (2024: $144,471,000) with a potential tax

benefit of $37,174,000 (2024: $31,554,000). The tax losses are split between the following jurisdictions:

Tax Losses

($000)

Tax Effect

($000)Rate

New Zealand 8,644 2,420 28%

Australia 11,320 3,396 30%

United States 149,324 31,358 21%

Tax losses are available to be carried forward and offset against future taxable income subject to the various

conditions required by income tax legislation being complied with.

Deferred Research and Development Tax Expenditure:

The Group also has deferred research and development tax expenditure of $67,113,000 (2024: $58,880,000) to

carry forward and claim for income tax purposes in New Zealand in the future. This has a tax effect of $18,792,000

(2024: $16,486,000). The deferred research and development tax expenditure can either be carried forward and

offset against future income arising from the research and development, or subject to meeting the shareholder

continuity requirements can be offset against future other taxable income.

Deferred Tax Assets:

The Group does not recognise a deferred tax asset in the Consolidated Balance Sheet.

Imputation Credit Account

The Group has imputation credits of Nil (2024: Nil).

Notes to the Consolidated Financial Statements

For the twelve months ended 31 March 2025

94

17. PAYABLES AND ACCRUALS
ACCOUNTING POLICY

Trade and Other Payables Due Within One Year

Trade payables are recognised at the value of the invoice received from a supplier. The carrying value of trade

payables is considered to approximate fair value as amounts are unsecured and are usually paid by the 30th of the

month following recognition.

GROUP

2025

($000)

2024

($000)

Trade Creditors 2,639 2,153

Accrued Expenses 1,265 711

Employee Entitlements (refer below) 4,140 3,889

Total Payables and Accruals 8,044 6,753

Payables and accruals are non-interest bearing and are normally settled on 30 day terms, therefore their carrying

value approximates their fair value.

The foreign currency split for Payables and Accruals is:

GROUP

2025

($000)

2024

($000)

NZD 2,218 2,122

AUD 1,043 202

USD 4,722 4,423

SGD - 6

CAD 61

-

8,044 6,753

Employee Entitlements

Employee entitlements are measured at values based on accrued entitlements at current rates of pay. These include

salaries and wages accrued up to balance date and annual leave earned to, but not yet taken at balance date.

GROUP

2025

($000)

2024

($000)

Payroll Taxes 192 264

Holiday Pay 634 606

Accrued Wages 3,275 3,019

Long Service Leave 39

-

Total Employee Entitlements 4,140 3,889

Notes to the Consolidated Financial Statements

For the twelve months ended 31 March 2025

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

95

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

18. SHARE CAPITAL

ACCOUNTING POLICY

Ordinary shares are described as equity.

Issue expenses, including commission paid, relating to the issue of ordinary share capital, have been written off

against the issued share price received and recorded in the Consolidated Statement of Changes in Equity.

Equity-settled share-based payments to employees and others providing services are measured at the fair value of

the equity instruments at the grant date. Details regarding the determination of the fair value of equity-settled share

based transactions are set out in Note 8.

GROUP

2025

($000)

2024

($000)

Ordinary Shares Authorised 294,458 294,400

Total Share Capital 294,458 294,400

All fully paid shares in the Group are Authorised and have equal voting rights and equal rights to dividends. All

Ordinary Shares are fully paid and have no par value.

Share Capital Group

2025 Shares

(000)

2025

($000)

2024 Shares

(000)

2024

($000)

Opening Balance 811,271 294,400 810,365 294,317

Issue of Ordinary Shares

- Employee Remuneration

1

645 58

906 83

Movement 645 58 906 83

Closing Balance 811,916 294,458 811,271 294,400


1) During the period 644,630 shares were issued as part of employees remuneration in lieu of cash payments at an average price of

$0.090 per share. (2024: 906,126 at $0.091).

There are 811,915,974 (March 2024: 811,271,344) ordinary shares on issue.

All fully paid shares in the Company have equal voting rights and equal rights to dividends. All Ordinary Shares are

fully paid and have no par value.

19. FOREIGN CURRENCY

ACCOUNTING POLICIES

Foreign Currency Transactions

The individual financial statements of the Group are presented in the currency of the primary economic environment

in which the entity operates (its functional currency). For the purpose of the Group financial statements, the results

and financial position of the Group entity are expressed in New Zealand dollars (‘NZ$’), which is the functional

currency of the Parent and the presentation currency for the Group financial statements.

In preparing the financial statements of the individual entities, transactions in currencies other than the entity’s

functional currency (foreign currencies) are recorded at the rates of exchange prevailing at the dates of the

transactions. At the end of each reporting period, monetary items denominated in foreign currencies are retranslated

at the rates prevailing at the end of the reporting period. Non monetary items denominated in foreign currencies are

translated at the rates prevailing on the date the transaction occurs.

96

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

Exchange differences are recognised in the Consolidated Statement of Comprehensive Income in the period in

which they arise.

Foreign Operations

For the purpose of presenting the Group financial statements, the assets and liabilities of the Group’s foreign

operations are expressed in New Zealand dollars using exchange rates prevailing at the end of the reporting

period. Income and expense items are translated at the average exchange rates for the period, unless exchange

rates fluctuated significantly during that period, in which case the exchange rates at the dates of the transactions

are used. Exchange differences arising, if any, are recognised in other comprehensive income and accumulated as

a separate component of equity in the Group’s foreign currency translation reserve. Such exchange differences

are reclassified from equity to profit or loss (as a reclassification adjustment) in the period in which the foreign

operation is disposed of.

Foreign Currency Translation Reserve

Exchange differences relating to the translation from the functional currencies of the Group’s foreign subsidiaries into

New Zealand dollars are brought to account by entries made directly to the Foreign Currency Translation Reserve.

20. RECONCILIATION OF CASH FLOWS TO OPERATING ACTIVITIES WITH OPERATING NET LOSS

GROUP

2025

($000)

2024

$000

Net Loss for the Period (29,936) (29,535)

Add Non Cash Items:

Depreciation 842 716

Loss (Gain) on disposal of Property, Plant and Equipment (19) 14

Amortisation 571 621

Employee Share options 1,317 1,189

Employee bonuses paid in shares in lieu of cash 58 83

Depreciation on right of use assets 1,344 1,267

Interest on finance leases shown in lease repayments 230 138

Total Non Cash Items 4,343 4,028

Add Movements in Other Working Capital items:

(Increase) Decrease in Receivables and Other Assets (576) 964

(Increase) Decrease in Inventory 81 (401)

Increase (Decrease) in Payables and Accruals 1,289 (174)

Effect of exchange rates on net cash 59 (632)

Total Movement in Other Working Capital 853 (243)

Net Cash Flows to Operating Activities (24,740) (25,750)

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

97

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

21. FINANCIAL INSTRUMENTS

ACCOUNTING POLICY

Foreign Currency Transactions

Financial instruments include cash and cash equivalents, short term deposits, receivables, security deposits, finance

lease liabilities and trade creditors. The particular recognition methods adopted are disclosed in the individual

policy statements associated with each item.

Managing Financial Risk

The Group’s activities expose it to the financial risks of changes in interest rate risk, credit risk, liquidity risk and

foreign currency risk. Management is of the opinion that the Company and the Group’s exposure to market risk

during the period and at balance date is defined as:

Risk FactorDescription

(i) Currency RiskFinancial assets and financial liabilities are denominated in NZD, USD, AUD, SGD,

CAD and EUR currencies

(ii) Interest Rate Risk Exposure to changes in Bank interest rates resulting in cash flow interest rate risk

(iii) Credit RiskRisk of financial loss if counterparty fails to meet contractual obligations

(iv) Liquidity RiskRisk the Group may not be able to meet its commitments as they fall due

(v) Other Price RiskNot applicable as no securities are bought, sold or traded

(i) Foreign Currency Risk

The Group faces the risk of movements in foreign currency exchange rates in relation to the New Zealand dollar.

The Group has significant operations in United States Dollars and less significant operations in Australian dollars,

Euros and Singapore dollars. As a result of this, the financial performance and financial position are impacted by

movements in exchange rates.

The Group manages foreign currency risk by purchasing overseas goods only when necessary and in line with the

approved treasury policy. It will also purchase foreign currency to fund overseas operations based on cash flow

forecasts in line with the approved treasury policy. There are no formal foreign currency hedges entered into.

A 10% increase or decrease in the foreign currency against the NZD will reduce/increase the loss reported by

approximately $180,000 (2024: $260,000) and increase/reduce equity by the same amount.

(ii) Interest Rate Risk

The Group’s interest rate risk arises from its cash and equivalents, and short term deposits. Cash and equivalents

comprise cash on hand and deposits at call with banks. Short term deposits comprise of term deposits placed with

New Zealand banks on fixed rates for different periods of time.

Management regularly review its banking arrangements to ensure it achieves the best returns on its funds while

maintaining access to necessary liquidity levels to service the Group’s day-to-day activities. The mixture of bank

deposits at floating interest rates and short term deposits at different rates over various periods of time mitigate

the risk of interest rates being received at less than market rates. The Group does not enter into interest rate

hedges.

A 1% increase or decrease in bank deposit interest rates will reduce/increase the loss reported by approximately

$214,000 and increase/reduce equity by the same amount (2024: $491,000).

(iii) Credit Risk

Credit risk is the risk of financial loss to the Group if a customer or counterparty to a financial instrument fails to

meet its contractual obligations.

The Group incurs credit risk from:

a) Cash and short term deposits;

b) Receivables in the normal course of its business; and

c) Other assets.

98

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

The Group has no significant concentration of credit risk other than bank deposits, with the exposure as at

31 March 2025 expressed as a percentage of total assets: 14.0% at ANZ, 12.5% at BNZ, 16.7% at Westpac, 14.8% at

Kiwibank and 2.8% at Wells Fargo. The Group’s cash and short term deposits are placed with high credit quality

financial institutions including major banks who have at least a A+ credit rating and concentrations are managed

within the approved treasury policy.

Regular monitoring of receivables is undertaken to ensure that the credit exposure remains within the Group’s

normal terms of trade. These receivables balances mainly relate to Kaiser Permanente, New Zealand customers,

and the New Zealand Government. Refer to note 10 for further details on expected credit losses for receivables.

The Group continues to invoice for every billable test completed in the US, and the billing and reimbursement

process continues to maximise the cash that is received by the Group. The Group has included an accrual for tests

performed from 1 April 2024 to 31 March 2025 for which payment has not been received by 31 March 2025.

Regular monitoring of other assets is undertaken to ensure that the credit exposure is limited.

The carrying values of financial assets represent the maximum exposure to credit risk as represented below:

GROUP

Notes

2025

($000)

2024

($000)

Cash and Cash Equivalents99,48229,261

Short Term Deposits913,08621,000

Trade and Other Receivables (excludes GST)104,9064,648

Other Assets (excludes prepayments)12 440 249

27,91455,158

(iv) Liquidity Risk

Liquidity risk is the risk that the Group may encounter difficulty in raising funds at short notice to meet its

commitments as they fall due. Management maintains sufficient cash balances and uses cash flow forecasts to

determine future cash flow requirements. Liquidity risk is managed within the approved treasury policy. The Group

has one external loan for $300,000 which relates to to the New Zealand Research and Development Tax Incentive

in-year payment loan scheme. The Group also has three finance leases.

Payables and Accruals totaling $7,863,000 are due within 3 months of balance date (2024: $6,753,000).

Fair Values

In the opinion of the Directors, the carrying amount of financial assets and financial liabilities approximate their fair

values at balance date.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

99

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

22. RELATED PARTIES

A shareholder, the University of Otago, provided services, including rental space, car parking and use of University

Equipment, to the Group to the value of $472,000 (2024: $493,000). The Group has commitments totaling

$368,000 (2024: $368,000) with the University of Otago in the next financial year.

Key Management Compensation

Key management personnel comprise of Directors and the Chief Executive Officer of Pacific Edge Limited, and the

President of Pacific Edge Diagnostics USA Limited.

Refer to Note 8 for details of the Incentive Plan that includes key management remuneration.

GROUP

2025

($000)

2024

($000)

Salaries and Other Short Term Employee Benefits2,5562,147

Share Options Benefits633646

Total Employee Entitlements3,1892,793

Directors’ Fees

The current total Directors’ fee pool for non-executive Directors of Pacific Edge Limited, approved by the

shareholders at the Annual Shareholders Meeting on the 29th July 2021 was $465,000 per annum and was based

on six Directors. With the addition of Tony Barclay on 21 March 2022, the number of Directors increased to seven.

In accordance with NZX Listing Rule 2.11.3 which permits an issuer to increase the aggregate amount payable to

the Directors to take into account an additional Director without shareholder approval, the pool for non-executive

Directors of Pacific Edge increased to $529,000. Mark Green ceased to be a Director on the 24th September

2024, reducing the pool back to $465,000 for the remainder of the financial year. The total amount of fees paid to

Directors for the year ended 31 March 2025 was $470,000 (2024: $500,000).

The table below sets out the total fees approved for non-executive Directors of Pacific Edge Limited for the year

ended 31 March 2025 based on the positions held:

Position

Quantity

2025

Fee per

Director

2025

($)

Total

Directors

Fees Paid

2025

($)

Quantity

2024

Fee per

Director

2024

($)

Total

Directors

Fees Paid

2024

($)

Chair1$115,000$115,0001$115,000$115,000

Deputy Chair 1$70,000$70,0001$70,000$70,000

Non-executive Directors

5 to Sept 24,

4 from Oct 24

$60,000$270,0005$60,000$300,000

Chair Audit & Risk Committee1$10,000$10,0001$10,000$10,000

Special Governance Allocation--$5,000--$5,000

Total Fee Pool$470,000$500,000

100

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

23. FINANCE AND OPERATING LEASE COMMITMENTS

ACCOUNTING POLICY

The Group leases various properties and equipment. Rental contracts vary depending on the type of asset

being leased. Lease terms are negotiated on an individual basis and contain a wide range of different terms and

conditions. The lease agreements do not impose any covenants, but leased assets may not be used as security for

borrowing purposes.

Contracts may contain both lease and non-lease components. The Group allocates the consideration in the

contract to the lease and non-lease components based on their relative stand-alone prices.

Leases are recognised as a right-of-use asset and a corresponding liability at the date at which the leased asset is

available for use by the Group. Each lease payment is allocated between the liability and finance cost. The finance

cost is charged to the Consolidated Statement of Comprehensive Income over the lease period to produce a

constant periodic rate of interest on the remaining balance of the liability for each period. The right-of-use asset is

depreciated over the shorter of the asset’s useful life and the lease term on a straight-line basis.

(i) Measurement basis

Assets and liabilities arising from a lease are initially measured on a present value basis. Lease liabilities include the

net present value of the following lease payments:

• fixed payments (including in-substance fixed payments), less any lease incentives receivable;

• variable lease payments that are based on an index or a rate;

• amounts expected to be payable by the lessee under residual value guarantees;

• the exercise price of a purchase option if the lessee is reasonably certain to exercise that option; and

• payments of penalties for terminating the lease, if the lease term reflects the lessee exercising that option.

Lease payments to be made under reasonably certain extension options are also included in the measurement of

the liability.

The lease payments are discounted using the interest rate implicit in the lease. If that rate cannot be readily

determined, which is generally the case for leases in the group, the lessee’s incremental borrowing rate is used. The

incremental borrowing rate is the rate that the individual lessee would have to pay to borrow the funds necessary

to obtain an asset of similar value to the right-of-use asset in a similar economic environment with similar terms,

security and conditions.

To determine the incremental borrowing rate, the Group:

• where possible, uses recent third-party financing received by the individual lessee as a starting point, adjusted to

reflect changes in financing conditions since third-party financing was received;

• uses a build-up approach that starts with a risk-free interest rate adjusted for credit risk for leases held by Pacific

Edge Limited, which does not have recent third-party financing; and

• makes adjustments specific to the lease, e.g. term, country, currency and security.

The Group is exposed to potential future increases in variable lease payments based on an index or rate, which are

not included in the lease liability until they take effect. When adjustments to lease payments based on an index or

rate take effect, the lease liability is reassessed and adjusted against the right-of-use asset.

Lease payments are allocated between principal and finance cost. The finance cost is charged to the Consolidated

Statement of Comprehensive Income over the lease period to produce a constant periodic rate of interest on the

remaining balance of the liability for each period.

Right-of-use assets are measured at cost comprising the following:

• the amount of the initial measurement of lease liability;

• any lease payments made at or before the commencement date;

• any initial direct costs; and

• restoration costs.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

101

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

Right-of-Use assets are generally depreciated over the shorter of the asset’s useful life and the lease term on

a straight-line basis. If the Group is reasonably certain to exercise a purchase option, the Right-of-Use asset is

depreciated over the underlying asset’s useful life.

Payments associated with short-term leases and leases of low-value assets are recognised on a straight-line basis

as an expense in profit or loss. Short-term leases are leases with a lease term of 12 months or less. Low-value assets

include IT equipment and small items of office furniture.

Right of Use Assets

GROUP

2025

($000)

2024

($000)

Cost

Opening Balance 7,997 4,191

Additions - 3,823

Removals (Leases Completed) (3,516) (134)

Foreign Currency Translation 151 117

Closing Balance 4,632 7,997


Accumulated Depreciation

Opening Balance 4,299 3,048

Depreciation 1,386 1,296

Reversal of Accumulated Depreciation (Leases Completed) (3,516) (134)

Foreign Currency Translation 18 89

Closing Balance 2,187 4,299

Net Right of Use Assets Balance 2,445 3,698

Right of Use Assets Net Book Value

Buildings 2,409 3,638

Computer Equipment 36 60

2,445 3,698

Depreciation

Buildings 1,360 1,261

Computer Equipment 26 35

1,386 1,296

Expenses relating to Short Term and Low Value Leases 131 147

Total Cash Outflow relating to Leases 1,496 1,406

102

Notes to the Consolidated Financial Statements
For the twelve months ended 31 March 2025

GROUP

Lease Liability

2025

($000)

2024

($000)

Opening Balance 3,773 1,222

Additions - 3,823

Lease Repayments (1,533) (1,406)

Interest Charged226 148

Foreign Currency Translation135 (14)

Closing Balance 2,601 3,773

Split by:

Current Liability 1,413 1,264

Non-Current Liability 1,188 2,509

2,601 3,773

The maturity of the Lease Liabilities is as follows:

Less than one year 1,413 1,264

One to two years 1,105 1,363

Two to three years 80 1,068

More than three years 3 78

2,601 3,773

24. OTHER COMMITMENTS AND CONTINGENT LIABILITIES

a) Contingent Liabilities

There were no known contingent liabilities at 31 March 2025 (March 2024: Nil). The Group has not granted any

securities in respect of liabilities payable by any other party whatsoever.

b) Capital Commitments

There are no capital commitments at 31 March 2025 (March 2024: Nil).

25. SUBSEQUENT EVENTS

Medicare Non-coverage of Cxbladder Tests

On 24 April 2025, Local Coverage Determination (L39365) ‘Genetic Testing in Oncology: Specific Tests’ became

effective in the US, halting Medicare coverage of Cxbladder tests.

Pacific Edge, which currently generates approximately 60% of its US revenue from Medicare and approximately

56% of total Operating Revenue, will now focus on the paths available, which include Medicare appeals for

Cxbladder Triage to get paid based on its inclusion in the AUA microhematuria guideline, despite the non-coverage

determination and reconsideration requests for Triage and Monitor.

Pacific Edge submitted a reconsideration request for Cxbladder Triage under ‘Biomarkers for Oncology’ LCD

(L35396) on 21 March 2025, a request that has already been deemed valid by Novitas, meaning they will now assess

the evidence submitted. During May 2025 Pacific Edge has also submitted a reconsideration request for Cxbladder

Monitor under ‘Genetic Testing in Oncology: Specific Tests’ (L39365) requesting non-coverage to be removed.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

103

However, Pacific Edge will not seek re-coverage of Cxbladder Detect as no new evidence has been published that
can be submitted for reconsideration. Detect users will be required to move over to Triage in an acceleration of a

plan intended to coincide with the commercial launch of Triage Plus.

Novitas controls the timeline for these reconsideration requests and is not bound by any maximum period to

complete this work. Industry experts typically estimate the time at 6-9 months for a valid submission of a single

product with only a small number of new supporting publications and not the protracted period of consultation

that results from creating a new LCD as was done with L39365.

Regarding Cxbladder Triage Plus, the Company will continue to develop, publish and subsequently submit a

reconsideration request in line with our previously published roadmap — those activities remain on track. The

Company will also continue to work with Kaiser Permanente on a peer-reviewed publication confirming the real-

world utility of Cxbladder Triage.

While the impact of ‘Genetic Testing for Oncology: Specific Tests’ (L39365) is expected to have a significant impact

on testing volume, Pacific Edge expects to continue to bill and receive reimbursement from contracted commercial

US payers without interruption, notably Kaiser Permanente, the US Veterans Administration, various Blue Cross

Blue Shield plans under the group purchasing agreement and from non-contracted private payers in line with

historic reimbursement rates. Similarly, Pacific Edge expects collections from our enhanced patient responsibility

and patient assistance programs to continue in line with the rates since the introduction of that program in July

2023.

The impact on revenue and revenue recognition is unable to be determined at this stage until the Group can

determine the impact of the non-coverage on the number of tests that the Company receives payment for and the

level of payment received.

Equity Raise

As detailed in the Going Concern section of Note 1 - Material Accounting Policy Information, to assist in the future

additional funding requirements of the Group. On 29 May 2025, the Board approved a capital raise which is being

progressed with the intention of raising at least $20m via a Placement and Share Purchase Plan. Completion of the

Placement will be dependent on shareholder approval, with anticipated settlement date no later than 31 August 2025.

Notes to the Consolidated Financial Statements

For the twelve months ended 31 March 2025


PricewaterhouseCoopers, PwC Centre, 60 Cashel Street, PO Box 13-244, Christchurch 8141, New Zealand

T: +64 3 374 3000, www.pwc.co.nz

Independent auditor’s report

To the shareholders of Pacific Edge Limited


Our opinion

In our opinion, the accompanying consolidated financial statements (the financial statements) of

Pacific Edge Limited (the Company), including its subsidiaries (the Group), present fairly, in all

material respects, the financial position of the Group as at 31 March 2025, its financial performance,

and its cash flows for the year then ended in accordance with New Zealand Equivalents to

International Financial Reporting Standards (NZ IFRS) and International Financial Reporting

Standards Accounting Standards (IFRS Accounting Standards).

What we have audited

The Group's financial statements comprise:

• the consolidated balance sheet as at 31 March 2025;

• the consolidated statement of comprehensive income for the year then ended;

• the consolidated statement of changes in equity for the year then ended;

• the consolidated statement of cash flows for the year then ended; and

• the notes to the financial statements, comprising material accounting policy information and other

explanatory information.

Basis for opinion

We conducted our audit in accordance with International Standards on Auditing (New Zealand) (ISAs

(NZ)) and International Standards on Auditing (ISAs). Our responsibilities under those standards are

further described in the Auditor’s responsibilities for the audit of the financial statements section of our

report.

We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis

for our opinion.

Independence

We are independent of the Group in accordance with Professional and Ethical Standard 1

International Code of Ethics for Assurance Practitioners (including International Independence

Standards) (New Zealand) (PES 1) issued by the New Zealand Auditing and Assurance Standards

Board and the International Code of Ethics for Professional Accountants (including International

Independence Standards) issued by the International Ethics Standards Board for Accountants (IESBA

Code), and we have fulfilled our other ethical responsibilities in accordance with these requirements.

Other than in our capacity as auditor, our firm carried out other assignments in the areas of other

services relating to half year review procedures, assurance on carbon emissions and the provision of

a training workshop. The firm has no other relationship with, or interests in, the Group.

Material uncertainty related to going concern

We draw attention to the disclosures in Note 1 to the financial statements, which indicates that the

Company incurred a net loss after tax of $29.936m (2024: loss of $29.535m) and had net cash

outflows from operating activities of $24.740m (2024: cash outflow $25.750m). The Company has

cash, cash equivalents and short term deposits of $22.568m at 31 March 2025. In addition,

subsequent to year end the Company lost Medicare coverage for its Cxbladder tests which represents

approximately 56% of operating revenue. An equity raise intended to raise at least $20m was

approved by the Directors on 29 May 2025, to be completed by 31 August 2025, to provide additional

funding.

As stated in Note 1, if the Company is unable to raise additional funds via the equity raise and control

its costs appropriately it may have insufficient funds to meet its obligations. These events or

conditions, along with other matters set forth in Note 1, indicate the existence of material uncertainties

that may cast significant doubt on the Company's ability to continue as a going concern. Our opinion is

not modified in respect of this matter.

104


PricewaterhouseCoopers, PwC Centre, 60 Cashel Street, PO Box 13-244, Christchurch 8141, New Zealand

T: +64 3 374 3000, www.pwc.co.nz

Independent auditor’s report

To the shareholders of Pacific Edge Limited


Our opinion

In our opinion, the accompanying consolidated financial statements (the financial statements) of

Pacific Edge Limited (the Company), including its subsidiaries (the Group), present fairly, in all

material respects, the financial position of the Group as at 31 March 2025, its financial performance,

and its cash flows for the year then ended in accordance with New Zealand Equivalents to

International Financial Reporting Standards (NZ IFRS) and International Financial Reporting

Standards Accounting Standards (IFRS Accounting Standards).

What we have audited

The Group's financial statements comprise:

• the consolidated balance sheet as at 31 March 2025;

• the consolidated statement of comprehensive income for the year then ended;

• the consolidated statement of changes in equity for the year then ended;

• the consolidated statement of cash flows for the year then ended; and

• the notes to the financial statements, comprising material accounting policy information and other

explanatory information.

Basis for opinion

We conducted our audit in accordance with International Standards on Auditing (New Zealand) (ISAs

(NZ)) and International Standards on Auditing (ISAs). Our responsibilities under those standards are

further described in the Auditor’s responsibilities for the audit of the financial statements section of our

report.

We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis

for our opinion.

Independence

We are independent of the Group in accordance with Professional and Ethical Standard 1

International Code of Ethics for Assurance Practitioners (including International Independence

Standards) (New Zealand) (PES 1) issued by the New Zealand Auditing and Assurance Standards

Board and the International Code of Ethics for Professional Accountants (including International

Independence Standards) issued by the International Ethics Standards Board for Accountants (IESBA

Code), and we have fulfilled our other ethical responsibilities in accordance with these requirements.

Other than in our capacity as auditor, our firm carried out other assignments in the areas of other

services relating to half year review procedures, assurance on carbon emissions and the provision of

a training workshop. The firm has no other relationship with, or interests in, the Group.

Material uncertainty related to going concern

We draw attention to the disclosures in Note 1 to the financial statements, which indicates that the

Company incurred a net loss after tax of $29.936m (2024: loss of $29.535m) and had net cash

outflows from operating activities of $24.740m (2024: cash outflow $25.750m). The Company has

cash, cash equivalents and short term deposits of $22.568m at 31 March 2025. In addition,

subsequent to year end the Company lost Medicare coverage for its Cxbladder tests which represents

approximately 56% of operating revenue. An equity raise intended to raise at least $20m was

approved by the Directors on 29 May 2025, to be completed by 31 August 2025, to provide additional

funding.

As stated in Note 1, if the Company is unable to raise additional funds via the equity raise and control

its costs appropriately it may have insufficient funds to meet its obligations. These events or

conditions, along with other matters set forth in Note 1, indicate the existence of material uncertainties

that may cast significant doubt on the Company's ability to continue as a going concern. Our opinion is

not modified in respect of this matter.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

105



PwC


Key audit matters

Key audit matters are those matters that, in our professional judgement, were of most significance in

our audit of the financial statements of the current year. These matters were addressed in the context

of our audit of the financial statements as a whole, and in forming our opinion thereon, and we do not

provide a separate opinion on these matters. In addition to the matter described in the Material

uncertainty related to going concern section, we have determined the matters described below to be

the key audit matters to be communicated in our report.

Description of the key audit matter

How our audit addressed the key audit

matter

Revenue recognition for US revenue

As disclosed in Note 5 of the consolidated financial

statements, the timing of revenue recognition for

US based revenue varies by revenue stream

between completion of the Cxbladder test and

receipt of cash. As disclosed in Note 5, US revenue

was $20.1m out of total operating revenue of

$21.8m for the year ending 31 March 2025.

The Company has three material United States

(US) revenue streams:

1. Coverage via Centers for Medicare and

Medicaid Services (CMS) and Medicare

Advantage;

2. Tests performed for Kaiser Permanente; and

3. Other private insurance.

In July 2020, the Company received Local

Coverage Determination ("LCD") and Local

Coverage Article (LCA) for CMS. This

determination created a set price for the Company's

tests of US$760 per test from July 2020, and

established a clear transaction price for the tests.

This transaction price, along with a history of

payment, satisfies the NZ IFRS requirement for

revenue recognition.

In the US derived revenue for tests performed for

CMS, Medicare Advantage, and Kaiser

Permanente have been recognised in advance of

cash being received. Revenue for these customers

is recognised once the test is invoiced.

All other US derived revenue is accounted for on a

cash receipt basis as disclosed in Note 5.

As disclosed in Note 25, subsequent to year end

Medicare ceased coverage of Cxbladder. Whilst

this does not have an impact on operating revenue

recognised in the current financial year, it does

create uncertainties regarding future operating

revenue.

We determined this to be a key audit matter due to

the significance of the judgements applied by

Directors for revenue recognition and the

significance of US revenue to the Company’s

operations.

Our audit procedures included the following:

We obtained an understanding of

management's processes and controls for

the CMS, Medicare Advantage, Kaiser

Permanente, and private insurance US

revenue streams, including the relevant

controls at the external billing

reimbursements service organisation.

We obtained the SOC1 System and

Organisation Controls Report for the external

billing reimbursement service organisation,

and evaluated the evidence provided over

the design and operating effectiveness of the

relevant controls.

We evaluated management's determination

of the timing of revenue recognition by:

● Assessing the data supporting revenue

recognition for CMS, Medicare

Advantage, and Kaiser Permanente to

confirm that the transaction price can be

determined and collectability is probable;

● Assessing the data supporting revenue

recognition for other private insurance to

confirm that the transaction price and

collectability is only probable when cash

is received;

● Performing subsequent receipt testing to

validate the probability of collection of

the year end receivables and performing

look back procedures over the prior year

receivables to test collection rates; and

● Evaluated whether revenue has been

recognised appropriately in accordance

with NZ IFRS 15.

We considered the appropriateness of

disclosures in the consolidated financial

statements.



PwC


Our audit approach

Overview


Overall group materiality: $545,000, which represents approximately 1%

of total expenses.

We chose total expenses as the benchmark because, in our view, it is

the benchmark against which the Group is most commonly measured by

users, and is generally accepted benchmark.

As reported above, we have one key audit matter, being:

• Revenue recognition for US revenue

As part of designing our audit, we determined materiality and assessed the risks of material

misstatement in the financial statements. In particular, we considered where management made

subjective judgements; for example, in respect of significant accounting estimates that involved

making assumptions and considering future events that are inherently uncertain. As in all of our

audits, we also addressed the risk of management override of internal controls, including among other

matters, consideration of whether there was evidence of bias that represented a risk of material

misstatement due to fraud.

Materiality

The scope of our audit was influenced by our application of materiality. An audit is designed to obtain

reasonable assurance about whether the financial statements are free from material misstatement.

Misstatements may arise due to fraud or error. They are considered material if, individually or in the

aggregate, they could reasonably be expected to influence the economic decisions of users taken on

the basis of the financial statements.

Based on our professional judgement, we determined certain quantitative thresholds for materiality,

including the overall Group materiality for the financial statements as a whole as set out above. These,

together with qualitative considerations, helped us to determine the scope of our audit, the nature,

timing and extent of our audit procedures, and to evaluate the effect of misstatements, both

individually and in the aggregate, on the financial statements as a whole.

How we tailored our group audit scope

We tailored the scope of our audit in order to perform sufficient work to enable us to provide an

opinion on the financial statements as a whole, taking into account the structure of the Group, the

accounting processes and controls, and the industry in which the Group operates.

Other information

The Directors are responsible for the other information. The other information comprises the

information included in the Annual Report, but does not include the financial statements and our

auditor’s report thereon. The Annual Report is expected to be made available to us after the date of

this auditor’s report.

Our opinion on the financial statements does not cover the other information and we will not express

any form of audit opinion or assurance conclusion thereon.

In connection with our audit of the financial statements, our responsibility is to read the other

information and, in doing so, consider whether the other information is materially inconsistent with the

financial statements or our knowledge obtained in the audit, or otherwise appears to be materially

misstated.

106



PwC


Our audit approach

Overview


Overall group materiality: $545,000, which represents approximately 1%

of total expenses.

We chose total expenses as the benchmark because, in our view, it is

the benchmark against which the Group is most commonly measured by

users, and is generally accepted benchmark.

As reported above, we have one key audit matter, being:

• Revenue recognition for US revenue

As part of designing our audit, we determined materiality and assessed the risks of material

misstatement in the financial statements. In particular, we considered where management made

subjective judgements; for example, in respect of significant accounting estimates that involved

making assumptions and considering future events that are inherently uncertain. As in all of our

audits, we also addressed the risk of management override of internal controls, including among other

matters, consideration of whether there was evidence of bias that represented a risk of material

misstatement due to fraud.

Materiality

The scope of our audit was influenced by our application of materiality. An audit is designed to obtain

reasonable assurance about whether the financial statements are free from material misstatement.

Misstatements may arise due to fraud or error. They are considered material if, individually or in the

aggregate, they could reasonably be expected to influence the economic decisions of users taken on

the basis of the financial statements.

Based on our professional judgement, we determined certain quantitative thresholds for materiality,

including the overall Group materiality for the financial statements as a whole as set out above. These,

together with qualitative considerations, helped us to determine the scope of our audit, the nature,

timing and extent of our audit procedures, and to evaluate the effect of misstatements, both

individually and in the aggregate, on the financial statements as a whole.

How we tailored our group audit scope

We tailored the scope of our audit in order to perform sufficient work to enable us to provide an

opinion on the financial statements as a whole, taking into account the structure of the Group, the

accounting processes and controls, and the industry in which the Group operates.

Other information

The Directors are responsible for the other information. The other information comprises the

information included in the Annual Report, but does not include the financial statements and our

auditor’s report thereon. The Annual Report is expected to be made available to us after the date of

this auditor’s report.

Our opinion on the financial statements does not cover the other information and we will not express

any form of audit opinion or assurance conclusion thereon.

In connection with our audit of the financial statements, our responsibility is to read the other

information and, in doing so, consider whether the other information is materially inconsistent with the

financial statements or our knowledge obtained in the audit, or otherwise appears to be materially

misstated.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

107



PwC


When we read the other information not yet received, if we conclude that there is a material

misstatement therein, we are required to communicate the matter to the Directors and use our

professional judgement to determine the appropriate action to take.

Responsibilities of the Directors for the financial statements

The Directors are responsible, on behalf of the Company, for the preparation and fair presentation of

the financial statements in accordance with NZ IFRS and IFRS Accounting Standards, and for such

internal control as the Directors determine is necessary to enable the preparation of financial

statements that are free from material misstatement, whether due to fraud or error.

In preparing the financial statements, the Directors are responsible for assessing the Group’s ability to

continue as a going concern, disclosing, as applicable, matters related to going concern, and using the

going concern basis of accounting unless the Directors either intend to liquidate the Group or to cease

operations, or have no realistic alternative but to do so.

Auditor’s responsibilities for the audit of the financial statements

Our objectives are to obtain reasonable assurance about whether the financial statements, as a

whole, are free from material misstatement, whether due to fraud or error, and to issue an auditor’s

report that includes our opinion. Reasonable assurance is a high level of assurance, but is not a

guarantee that an audit conducted in accordance with ISAs (NZ) and ISAs will always detect a

material misstatement when it exists. Misstatements can arise from fraud or error and are considered

material if, individually or in the aggregate, they could reasonably be expected to influence the

economic decisions of users taken on the basis of these financial statements.

A further description of our responsibilities for the audit of the financial statements is located at the

External Reporting Board’s website at:

https://www.xrb.govt.nz/standards/assurance-standards/auditors-responsibilities/audit-report-1-1/

This description forms part of our auditor’s report.

Who we report to

This report is made solely to the Company’s shareholders, as a body. Our audit work has been

undertaken so that we might state those matters which we are required to state to them in an auditor’s

report and for no other purpose. To the fullest extent permitted by law, we do not accept or assume

responsibility to anyone other than the Company and the Company’s shareholders, as a body, for our

audit work, for this report, or for the opinions we have formed.


The engagement partner on the audit resulting in this independent auditor’s report is Maxwell John

Dixon.



For and on behalf of:







PricewaterhouseCoopers Christchurch

29 May 2025

108

STATUTORY
INFORMATION

109

DIRECTORS’ INTERESTS
The company maintains an Interests Register in accordance with the Companies Act 1993 and the Financial

Markets Conduct Act 2013.

In addition to the Pacific Edge Group of companies, Directors disclosed interests, or cessation of interest,

in the following entities pursuant to section 140 of the Companies Act 1993 during the year ended

31 March 2025.

Director/EntityRelationship

C. Gallaher

Mariposa LtdChairman

Links Group Holdings LimitedChairman

Carisbrook Holdings LimitedChairman

Highlanders Rugby ClubDirector & Shareholder

S. Park

Even Capital GP LimitedDirector and Shareholder

National Provident FundIndependent Trustee

Orbis Diagnostics LimitedDirector and Shareholder

Rapid Response Nursing LimitedDirector and Shareholder

Scotch and Sparkles LimitedDirector and Shareholder

Annuitas Management LimitedDirector and Shareholder

Waiapu Anglican Social Services Trust Chair of Audit and Risk Committee

(ceased during the year)

B. Williams

Cartherics Pty LtdChairman and Shareholder

Pacifik Biopharma LtdDirector and Shareholder

Cleveland ClinicConsultant & Advisor

EngeneIC Pty LtdDirector and Shareholder

Zehna Therapeutics (wholly owned subsidiary of

the Cleveland Clinic)

Director

InnoPath TherapeuticsCSO, Director and Shareholder

A. Masfen

Albert Nominees LimitedDirector

Artemis Capital LimitedDirector

Masfen Securities LimitedDirector

Pure Food LimitedDirector and Shareholder

TBL Trustees LimitedDirector

TBL Holdings LimitedDirector

TecTrax LimitedDirector

Windfarm Group W2 LimitedDirector

A. Stove

Progressive Farms LtdDirector and Shareholder

Rua Bioscience LimitedChair and Shareholder

TAB NZChair

(ceased during the year)

M. Green (Retired 24 September2024)

Mariposa Holdings LimitedDirector

Obsidian Capital & Advisory LimitedDirector and Shareholder

Obsidian Capital Trust LimitedDirector and Shareholder

The Better Product GroupChair and Shareholder

T. Barclay

Baymatob Pty LimitedChair and Shareholder

Veripihi LimitedDirector and Shareholder

(ceased

during the year)

Rua Bioscience LimitedDirector and Shareholder

STATUTORY INFORMATION

FOR THE YEAR ENDED 31 MARCH 2025

110

DIRECTOR APPOINTMENT DATES
The dates below are the first appointment dates for all current Directors. Directors have been re-appointed

at Annual Shareholder Meetings, when retiring by rotation.

T. Barclay 21 March 2022

C. Gallaher 1 July 2016

M. Green 10 May 2021 - Retired 24 September 2024

A. Masfen 1 April 2008

S. Park 5 December 2018

A. Stove 15 March 2021

B. Williams 1 June 2013

DIRECTORS’ SECURITY HOLDINGS

Securities in the Company in which each Director and associated person of each Director, has a relevant

interest, are specified in the table below as at 31 March 2025. There were no Director share transactions

in FY 25.

Number of Equity Securities20252024

T. Barclay50,00050,000

C. Gallaher1,000,0001,000,000

A. Masfen9,320,0509,320,050

S. Park58,59158,591

A. Stove

5,0005,000

B. Williams

610,357610,357

INFORMATION USED BY DIRECTORS

The Board of Directors received no notices from Directors wishing to use Company information received in

their capacity as Directors, which would not have ordinarily been available.

INDEPENDENCE

The following Directors are considered by the Board to be independent, as defined under the NZX Main

Board Listing Rules, as at 31 March 2025:

T. Barclay, C. Gallaher, A. Masfen, S. Park, A. Stove, and B. Williams.

SUBSIDIARY COMPANY DIRECTORS

Section 211(2) of the Companies Act 1993 requires the company to disclose, in relation to its subsidiaries, the

total remuneration and value of other benefits received by Directors and former Directors, and particulars of

entries in the interests registers made during the year ended 31 March 2025.

No subsidiary has Directors who are not Directors of Pacific Edge Limited or employees of the Group. The

remuneration and other benefits of such Directors are included in the Directors Remuneration section of this

report and the remuneration and other benefits of employees totalling NZ$100,000 or more during the year

ended 31 March 2025 are included in the relevant bandings for remuneration above.

No remuneration is paid to any Director of a subsidiary company for their position as Director of that

subsidiary company.

The persons who held office as Directors of subsidiary companies at 31 March 2025 are as follows:

Pacific Edge Diagnostics New Zealand LimitedS. Park, A. Masfen, T. Barclay

Pacific Edge Analytical Services LimitedS. Park, A. Masfen, A. Stove

Pacific Edge Diagnostics USA LtdB. Williams, D. Levison, C. Gallaher, P. Meintjes

Pacific Edge (Australia) Pty LtdB. Williams, C. Gallaher, P. Meintjes

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

111

TWENTY LARGEST EQUITY SECURITY SHAREHOLDERS AS AT 31 MAY 2025
RankRegistered ShareholderNumber of Shares% of Total Shares

1New Zealand Central Securities Depository Limited279,747,055 34.5

2New Zealand Depository Nominee47,196,270 5.8

3FNZ Custodians Limited41,410,698 5.1

4Forsyth Barr Custodians Limited30,615,190 3.8

5Masfen Securities Limited30,121,378 3.7

6K One W One Limited21,091,520 2.6

7Custodial Services Limited13,438,560 1.7

8JBWERE (Nz) Nominees Limited8,178,935 1.0

9Leveraged Equities Finance Limited7,186,559 0.9

10Minggang Chen6,000,000 0.7

11Carol Anne Edwards & Graeme Brent Ramsey5,537,037 0.7

12Adrian James Harvey & Joanne Elizabeth Harvey5,165,936 0.6

13Jason Robert Gilder3,977,570 0.5

14Steven Cyril Hancock & Bronwyn Hilda Hancock3,200,000 0.4

15Ballynagarrick Investments Limited2,615,671 0.3

16Lennon Holdings Limited2,610,442 0.3

17Zhen Chen2,600,000 0.3

18Yongpei Huang2,467,101 0.3

19Jingli Fan2,455,348 0.3

20Christopher Israel Prince Chellappa2,359,063 0.3

Total 572,135,762 63.8

SHAREHOLDERS HELD THROUGH NZCSD AS AT 31 MAY 2025

New Zealand Central Securities Depository Limited (NZCSD) provides a custodian depository service that

allows electronic trading of securities to its members and does not have a beneficial interest in these shares.

As at 31 May 2025, the ten largest shareholdings in the company held through NZCSD were:

RankRegistered ShareholderNumber of Shares% of Total Shares

1Premier Nominees Limited86,385,377 10.6

2HSBC Nominees (New Zealand) Limited50,607,517 6.2

3Tea Custodians Limited25,994,888 3.2

4Bnp Paribas Nominees NZ Limited Bpss4025,017,864 3.1

5Accident Compensation Corporation22,303,750 2.8

6Private Nominees Limited20,478,479 2.5

7Citibank Nominees (Nz) Ltd15,291,426 1.8

8JPMORGAN Chase Bank12,021,141 1.5

9Premier Nominees Limited11,359,918 1.4

10Public Trust Rif Nominees Limited3,392,896 0.4

TOTAL272,853,256 33.6

112

SPREAD OF SECUITY HOLDERS AS AT 31 MAY 2025
No. of Ordinary

Security Holders

% of Issued

Capital

1 – 1,0008230.1

1,001 – 5,0001,8320.6

5,001 – 10,0001,0981.0

10,001 – 50,0001,9885.7

50,001 – 100,0004854.3

Greater than 100,00164488.2

Total Security Holders6870100.00

SUBSTANTIAL PRODUCT HOLDERS

The following substantial product holder information is given pursuant to section 293 of the Financial

Markets Conduct Act 2013. These substantial product holders are shareholders who have a relevant interest

of 5% or more of a class of quoted voting products of the Company.

As at 31 March 2025, details of the substantial product holders of the Company and their relevant interests

in the Company’s Shares are as follows:

Name of Substantial Product HolderNumber of Ordinary

Voting Securities

as at 31 March 2025% of Issued Capital

First Cape Group 106,376,149 13.1

ANZ New Zealand Investments Limited, ANZ Bank New

Zealand Limited and ANZ Custodial Services NZ Ltd

120,370,47214.9

Westpac Banking Corporation52,810,3846.5

DONATIONS

The Group made no donations during the year.

CREDIT RATING

The Company currently does not have a credit rating.

WAIVERS FROM NZX LISTING RULES

No waivers were granted by NZX during the year ended 31 March 2025.

EXERCISE OF NZX POWERS (LISTING RULE 9.9.3)

NZX did not exercise its powers during the year under Listing Rule 9.9.3.

PACIFIC EDGE LIMITED ANNUAL REPORT 2025

113

COMPANY DIRECTORY
As at 31 March 2025

Issued Capital

811,915,974 Ordinary Shares

Registered Office

Level 12, Otago House

Cnr Moray Place and Princes Street

Dunedin

Directors

C. Gallaher — Chairman

B. Williams — Deputy Chairman

A. Masfen

S. Park

A. Stove

M. Green (Retired 24 September 2024)

T. Barclay

Chief Executive Officer

Peter Meintjes

Chief Financial Officer

Grant Gibson

Nature of Business

Research, develop and commercialise new

diagnostic and prognostic tools for the early

detection and management of cancers.

Auditors

PricewaterhouseCoopers

Christchurch

Bankers

Bank of New Zealand

Dunedin

ANZ

Dunedin

Kiwibank

Dunedin

Westpac

Dunedin

Wells Fargo

San Francisco

Solicitors

Anderson Lloyd

Level 12, Otago House

Cnr Moray Place and Princes Street

Dunedin

Securities Registrar

MUFG Corporate Markets

138 Tancred Street

Ashburton

Company Number

1119032

Date of Incorporation

27 February 2001


PACIFIC EDGE COMMUNICATIONS


Websites

www.pacificedgedx.com

www.cxbladder.com

Facebook

www.facebook.com/PacificEdgeLtd

www.facebook.com/Cxbladder


Twitter

@PacificEdgeLtd

@Cxbladder


LinkedIn

www.linkedin.com/company/pacific-edge-ltd

114

87 St David Street, PO Box 56, Dunedin, New Zealand
P 0800 555 563 (NZ), +64 3 577 6733 (Outside NZ) F +64 3 974 9393

www.pacificedgedx.com

Data sourced from publicly available filings. Our datasets may not be complete. Automated analysis can produce errors. If you believe any data on this page is incorrect, please contact us at hello@nzxplorer.co.nz. For informational purposes only. Not investment advice.