Leading Singapore Hospital Now Ordering Cxbladder

3 March 2026
LEADING SINGAPORE HOSPITAL NOW ORDERING CXBLADDER
DUNEDIN, New Zealand – Cancer diagnostics company Pacific Edge (NZX, ASX: PEB) today
announces its Dunedin laboratory has signed a service agreement with Singapore General
Hospital (SGH), an important milestone in the company’s strategy to drive the adoption of its
tests in the Asia Pacific.
Physicians and clinicians at SGH may now order Cxbladder Triage or Triage Plus for the
evaluation of patients presenting with hematuria, and Cxbladder Monitor for the surveillance
of bladder cancer recurrence.
SGH is government funded, and the largest and oldest hospital in Singapore, serving a
population of more than 1 million patients annually
1
.
SGH is committed to reducing unnecessary or unwanted cystoscopies, and the initial clinical
implementation will focus on offering microhematuria patients Triage Plus and offering Monitor
to lower risk NMIBC
2
patients on surveillance as an alternative to reduce the frequency of
cystoscopy. Patients may be required to pay for the tests, so will be given the choice of a
cystoscopy or Cxbladder.
While initial monthly volumes are expected to be modest as clinical teams become familiar
with Cxbladder testing, Pacific Edge is seeking to leverage this success with other regional
hospitals and clinicians, given the leading role SGH plays in setting the standards for
healthcare across the Asia Pacific region.
Pacific Edge Chief Executive Dr Peter Meintjes said: “We’re delighted to be supporting
Singapore General Hospital as they implement Cxbladder testing for their hematuria and
NMIBC patients.
“The clinical benefits of our non-invasive genomic urine tests are well established with the
inclusion of Cxbladder Triage in the AUA/SUFU Microhematuria Guideline
3
and from the real-
world evidence in New Zealand and the Kaiser Permanente system in the US. The tests
demonstrated economic benefits
4
are meanwhile particularly important in public or other
capitated systems. Cxbladder will reduce the volume of unnecessary cystoscopies, help
clinical teams streamline resource utilization, and improve day-to-day patient care for those
patients most in need,” Dr Meintjes said.

1
https://www.sgh.com.sg/about-sgh/who-we-are
2
NMIBC is non-muscle invasive bladder cancer
3
Barocas DA, Lotan Y, Matulewicz RS, Raman JD, Westerman ME, Kirkby E, Pak L, Souter L. Updates to
Microhematuria: AUA/SUFU Guideline (2025). J Urol. 0(0). doi: 10.1097/JU.0000000000004490
Barocas et al. (2025). Updates to Microhematuria: AUA/SUFU Guideline (2025). The Journal of urology, 213(5),
547–557. https://doi.org/10.1097/JU.0000000000004490.
4
Tyson et al (2024) Budgetary Impact of Including the Urinary Genomic Marker Cxbladder Detect in the Evaluation
of Microhematuria Patients - PubMed (PMID: 37914255)

2
“We are working closely with SGH, recognizing the important role the hospital and its clinicians
play in driving clinical practice change across the country and the entire Asia Pacific region.”
Triage Plus is the next generation test from Pacific Edge – a multi-modal (RNA and DNA)
urine-based genomic test with substantially improved performance characteristics when
contrasted with Pacific Edge’s first-generation tests, Triage and Detect for hematuria
evaluation.
With the recent publication of the DRIVE study
5
in the Journal of Urologic Oncology providing
an independent clinical validation, Triage Plus builds on the performance of Cxbladder Triage,
a test now included in the AUA Guideline supported with ‘Grade A’ evidence from the first ever
randomized controlled trial of a urine biomarker (STRATA
6
). Triage Plus is available
throughout the Asia Pacific region to Australian, New Zealand and Southeast Asian
customers.
Released for and on behalf of Pacific Edge by Grant Gibson, Chief Financial Officer.
Pacific Edge: www.pacificedgedx.com
Pacific Edge Limited (NZX/ ASX: PEB) is a global cancer diagnostics company leading the
way in the development and commercialization of bladder cancer diagnostic and prognostic
tests for patients presenting with hematuria or surveillance of recurrent disease.
Headquartered in Dunedin, New Zealand, the company provides its suite of Cxbladder tests
globally through its wholly owned, and CLIA certified, laboratories in New Zealand and the
USA.
Cxbladder: www.cxbladder.com
Cxbladder is a suite of non-invasive genomic urine tests optimized for the risk stratification of
urothelial cancer in patients presenting with microhematuria and those being monitored for
recurrent disease. The tests help improve the overall patient experience, while prioritizing time
and clinical resources to optimize practice workflow and improve efficiency.
Supported by over 20 years of research, Cxbladder’s evidence portfolio extends to more than
25 peer reviewed publications, and Cxbladder Triage is now included in the American
Urological Association’s Microhematuria Guideline. To drive increased adoption and improved
patient health outcomes, Cxbladder is the focal point of numerous ongoing and planned
studies designed to generate further clinical utility evidence.
Cxbladder is available in the US, Australasia, and Israel and in markets throughout Asia and
South America. In the US, the test has been used by over 5,000 urologists who have ordered

5
Savage et al. (2025). Diagnostic performance of Cxbladder Triage Plus for the identification and stratification of
patients at risk for urothelial carcinoma: The multicenter, prospective, observational DRIVE study. Urologic
oncology, S1078-1439(25)00405-3. Advance online publication. https://doi.org/10.1016/j.urolonc.2025.10.008
6
Lotan et al. (2024). A Multicenter Prospective Randomized Controlled Trial Comparing Cxbladder Triage to
Cystoscopy in Patients With Microhematuria. The Safe Testing of Risk for Asymptomatic Microhematuria Trial. The
Journal of Urology Vol 212(1) 41-51.

3
more than 130,000 tests. In New Zealand, Cxbladder is accessible to around 70% of the
population via public healthcare and all residents have the option of buying the test online.